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Genetic Vectors

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Definition: DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.  coord with specific bacterium, virus, phage or plasmid   
See Also Bacteriophages; DNA, Recombinant; Viruses
Examples Chromosomes, Artificial; Cosmids
Other names Vectors, Genetic; Shuttle Vectors; Cloning Vectors; Vectors, Shuttle; Vectors, Cloning; Vector, Shuttle; Vector, Genetic; Vector, Cloning; Shuttle Vector; Genetic Vector; Cloning Vector
 
SubstanceCAS Registry & nameCategoriesSource
AdGVVEGF121.10  0   *Lymphokines *Angiogenic Proteins Genetic Vectors Gene Therapy. Curr Opin Investig Drugs 2001 Jun;2(6):792-5
poly(2-aminoethyl propylene phosphate)  0   *Organophosphorus Compounds *Polymers Genetic Vectors. J Am Chem Soc 2001 Sep 26;123(38):9480-1
GD5 protein, recombinant  0   *Diphtheria Toxin *Recombinant Fusion Proteins *Receptor, erbB-2 *Single-Chain Antibodies Genetic Vectors. J Biol Chem 1998 Apr 10;273(15):8835-41
3-(N(4)-(N(1),N(8)-diguanidinospermidine)carbamoyl)cholesterol  0   *Guanidines Cholesterol/*analogs & derivatives Genetic Vectors. Proc Natl Acad Sci U S A 1996 Sep 3;93(18):9682-6
3-((N',N'-diguanidinoethylaminoethyl)carbamoyl)cholesterol  0   *Guanidines Cholesterol/*analogs & derivatives Genetic Vectors. Proc Natl Acad Sci U S A 1996 Sep 3;93(18):9682-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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