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Glaucoma

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Definition: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)  differentiate from OCULAR HYPERTENSION; / surg: consider FILTERING SURGERY or SCLEROSTOMY or TRABECULECTOMY   
See Also Filtering Surgery; Iridocorneal Endothelial Syndrome; Sclerostomy; Trabeculectomy
Examples Glaucoma, Angle-Closure; Glaucoma, Neovascular; Glaucoma, Open-Angle
Other names Glaucomas
 
SubstanceCAS Registry & nameCategoriesSource
Ganfort  0   *Amides *Timolol Cloprostenol/*analogs & derivatives Drug Combinations Antihypertensive Agents Glaucoma/drug therapy. Oftalmologia. 2011;55(3):53-69
Duotrav  0   *Timolol Cloprostenol/*analogs & derivatives Drug Combinations Antihypertensive Agents Glaucoma/drug therapy. Oftalmologia. 2011;55(3):53-69
Xalacom  0   *Prostaglandins F, Synthetic *Timolol Drug Combinations Antihypertensive Agents Glaucoma/drug therapy. Oftalmologia. 2011;55(3):53-69
Azarga  0   *Sulfonamides *Thiazines *Timolol Drug Combinations Antihypertensive Agents Glaucoma/drug therapy. Oftalmologia. 2011;55(3):38-46
MacKay Shek Carr syndrome  0   *Glaucoma *Retinal Degeneration.
Ackerman syndrome  0   *Glaucoma *Tooth Abnormalities *Maxillofacial Abnormalities.
Bowen syndrome  0   *Abnormalities, Multiple *Contracture *Glaucoma *Facies.
Friedreich ataxia congenital glaucoma  0   *Friedreich Ataxia *Glaucoma.
Peters anomaly with cataract  0   *Cataract *Glaucoma/congenital.
Ghose Sachdev Kumar syndrome  0   *Glaucoma *Microphthalmos *Retinal Dystrophies.
GEMSS syndrome  0   *Abnormalities, Multiple *Ectopia Lentis *Glaucoma *Growth Disorders *Joint Diseases.
Microcornea, glaucoma, and absent frontal sinuses  0   *Eye Abnormalities *Glaucoma Cornea/abnormalities Frontal Sinus/abnormalities.
Lowry Maclean syndrome  0   *Abnormalities, Multiple *Cleft Palate *Craniosynostoses *Diaphragmatic Eventration *Glaucoma *Growth Disorders *Heart Defects, Congenital *Intellectual Disability *Osteogenesis Imperfecta.
Glaucoma 3, primary infantile, B  0   *Glaucoma.
Tetralogy of fallot and glaucoma  0   *Glaucoma *Tetralogy of Fallot.
Iris hypoplasia and glaucoma  0   *Glaucoma *Retinal Diseases/congenital.
Iridogoniodysgenesis, dominant type  0   *Eye Abnormalities *Glaucoma *Iris Diseases *Tooth Abnormalities Anterior Chamber/abnormalities.
Iridogoniodysgenesis type1  0   *Eye Abnormalities *Glaucoma *Iris Diseases.
Charcot-Marie-Tooth disease, Type 4B2, with early-onset glaucoma  0   *Glaucoma *Charcot-Marie-Tooth Disease.
bimatoprost  0 5-Heptenamide, 7-(3,5-dihydroxy-2-(3-hydrdoxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (1R-(1alpha(Z),2beta(1E,3S*),3alpha,5alpha))  *Amides Cloprostenol/*analogs & derivatives Glaucoma Ocular Hypertension.
Pharma Action Antihypertensive Agents
Am J Ophthalmol. 2001 Jan;131(1):19-24LATISSE; LUMIGAN; BIMATOPROST
proxopheline  0   *Clonidine *Oxadiazoles Drug Combinations Glaucoma Ophthalmic Solutions. Vestn Oftalmol 1998 May-Jun;114(3):3-4
FOXC1 protein, human  0   *Forkhead Transcription Factors Glaucoma. Nat Genet 1998 Jun;19(2):140-7
trabecular meshwork-induced glucocorticoid response protein  0   *Cytoskeletal Proteins *Eye Proteins *Glycoproteins Glaucoma Trabecular Meshwork Leucine Zippers. Science 1996 Jan 31;275(5300):668-70

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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