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Glucosinolates

More information in Books or onNLM PubMed
Definition: Substituted thioglucosides. They are found in rapeseed (Brassica campestris) products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-methoxyindol-3-ylmethylglucosinolate  0   *Glucosinolates *Indoles. New Phytol. 2011 Nov;192(3):713-26
B221 compound  0   *Glucosinolates. Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(8):980-3
A209 compound  0   *Glucosinolates. Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(8):980-3
neoglucobrassicin  0   *Glucosinolates *Indoles. Biol Chem 2010 Nov;391(11):1281-93
3-butenyl glucosinolate  0   *Glucosinolates. Biosci Biotechnol Biochem 2010 Jun 23;74(6):1286-9
putranjivine  0   *Glucosinolates *Sulfuric Acid Esters. J Ethnopharmacol 2010 Feb 17;127(3):731-6
glucoraphenin  0   *Glucosinolates. Bioorg Med Chem 1997 Sep;5(9):1799-806
2-(2,3-2H2)propenyl glucosinolate  0   *Glucosinolates. Phytochemistry 2007 May;68(10):1384-90
4-(cystein-S-yl)butyl glucosinolate  0   *Glucosinolates Cysteine/*analogs & derivatives. Biosci Biotechnol Biochem 2007 Jan;71(1):114-21
glucocochlearin  0   *Glucosinolates *Sulfuric Acids. Carbohydr Res 2006 Sep 4;341(12):2166-9
4-methylthio-3-butenyl glucosinolate  0   *Glucosinolates. J Agric Food Chem. 2005 Dec 28;53(26):9890-6
4-(glucopyranosyldisulfanyl)butyl glucosinolate  0   *Disulfides *Glucosinolates. Biosci Biotechnol Biochem 2004 Dec;68(12):2444-50
4-mercaptobutyl glucosinolate  0   *Glucosinolates. Phytochemistry 2002 Sep;61(1):25-30
prolinium 4-(methylsulfinyl)butylglucosinolate  0   *Glucosinolates. Fitoterapia 2002 Apr;73(2):177-8
glucoiberin  0   *Glucosinolates. J Nat Prod 2002 Apr;65(4):517-22
gluconasturtiin  499-30-9   *Glucosinolates. Fitoterapia 2001 Nov;72(7):760-4
1,4-dimethoxyindol-3-ylmethylglucosinolate  0   *Glucosinolates *Indoles. J Agric Food Chem 2001 Mar;49(3):1502-7
4-hydroxyindol-3-ylmethylglucosinolate  0   *Indoles *Glucosinolates. J Agric Food Chem 2001 Mar;49(3):1502-7
methoxyglucobrassicin  0   *Glucosinolates. J Chromatogr A 1999 Dec 9;864(1):155-62
glucoraphanin  0   *Glucosinolates *Imidoesters. Bioorg Med Chem Lett 1999 Apr 5;9(7):1047-8
4-hydroxybenzylglucosinolate  0   *Glucosinolates. Proc Natl Acad Sci U S A 1995 Dec 19;92(26):12505-9
1-methoxy-3-indolylmethylglucosinolate  5187-84-8   *Glucosinolates *Indoles Brassicaceae. Phytochemistry 1990;29(4):1315
2-hydroxybut-3-enylglucosinolate  31362-92-2 beta-D-Glucopyranose, 1-thio-, 1-(3-hydroxy-N-(sulfooxy)-4-pentenimidate)  *Glucosinolates Brassicaceae. Phytochemistry 1990;29(4):1315
glucobrassicin  4356-52-9   *Glucosinolates *Indoles. Hum Toxicol 1986;5(1):15
4-methoxy-3-indolylmethyl glucosinolate  83327-21-3 beta-D-Glucopyranose, 1-thio-, 1-(4-methoxy-N-(sulfooxy)-1H-indole-3-ethanimidate)  *Glucosinolates *Indoles Plant Extracts. Biochem Biophys Res Commun 1982;107(4):1368
4-hydroxy-3-indolylmethylglucosinolate  83327-20-2 beta-D-Glucopyranose, 1-thio-, 1-(4-hydroxy-N-(sulfooxy)-1H-indole-3-ethanimidate)  *Glucosinolates *Indoles. Biochem Biophys Res Commun 1982;107(4):1258
sinigrin  534-69-0   *Glucosinolates. Can J Biochem 53(5):630;1975
progoitrin  585-95-5   *Glucosinolates. Can J Biochem 51(12):1654;1973; Poult Sci 55(3):861;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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