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Glutathione Transferase

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Definition: A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.     
Examples Glutathione S-Transferase pi 		Other names S-Hydroxyalkyl Glutathione Lyase; Ligandins; Glutathione S-Epoxidetransferase; Glutathione S-Aryltransferase; Glutathione S-Alkyltransferase; Transferases, Glutathione; Transferase, Glutathione; Transferase mu, Glutathione; Transferase E, Glutathione; Transfer Protein, Heme; S-Transferase, Glutathione; S-Transferase P, Glutathione; S-Transferase III, Glutathione; S-Transferase C, Glutathione; S-Transferase B, Glutathione; S-Transferase A, Glutathione; S-Transferase 3, Glutathione; S-Epoxidetransferase, Glutathione; S-Aryltransferase, Glutathione; S-Alkyltransferase, Glutathione
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-O-decyl-gabosine D  0   *Cyclohexanones Glutathione Transferase/antagonists & inhibitors. J Med Chem. 2011 Dec 22;54(24):8574-81.
ethacraplatin  0   *Organoplatinum Compounds Ethacrynic Acid/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors. J Am Chem Soc. 2005 Feb 9;127(5):1382-3.
glutathione transferase kappa, mouse  EC 2.5.1.18   *Glutathione Transferase. Lab Invest. 2011 Nov;91(11):1572-83
glutathione S-transferase M5, mouse  EC 2.5.1.18   *Glutathione Transferase. Mol Reprod Dev 2009 Apr;76(4):379-88
GSTA4-4 protein, mouse  EC 2.5.1.18   *Glutathione Transferase. J Biol Chem 1994 Jan 14;269(2):992-1000
technetium 99m C2A-glutathione transferase  0   *Recombinant Fusion Proteins *Organotechnetium Compounds Glutathione Transferase. J Nucl Med 2006 Aug;47(8):1367-74
GSTO-1 protein, C elegans  EC 2.5.1.18   *Glutathione Transferase *Caenorhabditis elegans Proteins. FASEB J 2008 Feb;22(2):343-54
glutathione S-transferase M5, human  EC 2.5.1.18   *Glutathione Transferase. Br J Nutr 2007 May;97(5):883-90928-37
DHAR1 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. J Biol Chem 2007 Mar 23;282(12):8786-92
YfcG protein, E coli  EC 2.5.1.18   *Glutathione Transferase *Escherichia coli Proteins. J Biochem (Tokyo) 2006 Nov;140(5):703-11
YfcF protein, E coli  EC 2.5.1.18   *Glutathione Transferase *Escherichia coli Proteins. J Biochem (Tokyo) 2006 Nov;140(5):703-11
GSTU26 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Plant Cell Rep 2006 Sep;25(9):997-1005
GSTF9 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Plant Cell Rep 2006 Sep;25(9):997-1005
GSTM4 protein, human  EC 2.5.1.18   *Glutathione Transferase. Gene 2006 Sep 1;379:148-55
alanyl-prolyl-tryptophyl-cysteine  0   *Oligopeptides Glutathione Transferase. Peptides 2006 Sep;27(9):2069-74
1-Cys thiol transferase protein, S cerevisiae  EC 2.5.1.18   *Glutathione Transferase *Saccharomyces cerevisiae Proteins. Biochem J. 2006 Sep 1;398(2):187-96
gamma-(gamma-oxa)glutamyl-(9-fluorenylmethyl)-cysteinyl-glycine  0   *Fluorenes Glutathione/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors. Amino Acids 2005 Nov;29(3):255-61
gamma-glutamyl-(9-fluorenylmethyl)-cysteinyl-glycine  0   *Fluorenes Glutathione/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors. Amino Acids 2005 Nov;29(3):255-61
Gstz1 protein, mouse  EC 2.5.1.-   *Glutathione Transferase.
Gstz1 protein, rat  EC 2.5.1.-   *Glutathione Transferase.
glutathione S-transferase A3-3, human  EC 2.5.1.18   *Glutathione Transferase. Biochemistry 2004 Dec 21;43(50):15673-9
glutathione transferase T1-1, human  EC 2.5.1.18   *Glutathione Transferase. Chem Res Toxicol 2003 Nov;16(11):1493-9
glutathione transferase 5-5, rat  EC 2.5.1.18   *Glutathione Transferase. Chem Res Toxicol 2003 Nov;16(11):1493-9
GFZF protein, Drosophila  0   *Carrier Proteins Glutathione Transferase Zinc Fingers. Gene 2004 Nov 10;342(1):49-56
GSTO2 protein, human  EC 2.5.1.18   *Glutathione Transferase. Neurology 2004 May 25;62(10):1910-1
GSTT2 protein, human  EC 2.5.1.-   *Glutathione Transferase.
GSTO1 protein, human  EC 2.5.1.18   *Glutathione Transferase. Hum Mol Genet 2003 Dec 15;12(24):3259-67
GST11 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Plant Physiol 2004 Apr;134(4):1672-82
GST1 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Plant Physiol 2004 Apr;134(4):1672-82
GSTK1 protein, human  EC 2.5.1.18   *Glutathione Transferase. J Biol Chem 2004 Apr 16;279(16):16246-53
glutathione-S-transferase-III-1H,8-10  0   *Fibronectins *Peptide Fragments Glutathione Transferase. J Cell Biol 2002 Jul 8;158(1):175-84
glutathione S-transferase 1-1, kappa, rat  EC 2.5.1.18   *Glutathione Transferase. Biochemistry 2004 Jan 20;43(2);352-61
GSTA1 protein, human  EC 2.5.1.18   *Glutathione Transferase.
Gstt2 protein, mouse  EC 2.5.1.-   *Glutathione Transferase.
TRANSPARENT TESTA 19 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Plant J 2004 Jan;37(1):104-14
28-kilodalton glutathione S-transferase antigen, Schistosoma mansoni  EC 2.5.1.18   *Antigens, Bacterial *Glutathione Transferase. Clin Diagn Lab Immunol 2003 Jul;10(4):536-41
GSTF8 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Mol Plant Microbe Interact 2004 Jan;17(1):70-80
GSTM3 protein, human  EC 2.5.1.18   *Glutathione Transferase. Prostate. 2004 Mar 1;58(4):414-20
mGSTA4-4  EC 2.5.1.18   *Glutathione Transferase. Toxicol Appl Pharmacol. 2004 Feb 1;194(3):296-308
glutathione transferase sigma, Xenopus  EC 2.5.1.18   *Glutathione Transferase *Xenopus Proteins. Arch Biochem Biophys. 2003 Nov 15;419(2):214-21
GSTF6 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Plant Cell Physiol 2003 Jul;44(7):750-7
GSTF2 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Plant Cell Physiol 2003 Jul;44(7):750-7
O(1)-hexadecyl-gamma-glutamyl-S-benzylcysteinyl-phenylglycine ethyl ester  0   *Oligopeptides Glutathione Transferase/antagonists & inhibitors. J Pharmacol Exp Ther 2003 Sep;306(3):861-9
GSTU19 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Plant Physiol 2002 Nov;130(3):1497-505
GST1 protein, Plasmodium falciparum  EC 2.5.1.18   *Glutathione Transferase *Protozoan Proteins. Mol Biochem Parasitol 2002 Sep-Oct;124(1-2):85-90
GSTM1-1 protein, Xenopus  EC 2.5.1.-   *Glutathione Transferase. Biochem J 2002 Aug 1;365(Pt 3);685-91
MdGST-6A  EC 2.5.1.-   *Glutathione Transferase. Insect Biochem Mol Biol 2001 Nov 1;31(12):1145-53
GSTZ1 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins. Arch Biochem Biophys 2000 Dec 15;384(2):407-12
28 kDa gluthathione S-transferase antigen, Schistosoma haematobium  EC 2.5.1.-   *Antigens, Helminth *Glutathione Transferase *Helminth Proteins. Clin Exp Immunol 2001 Apr;124(1):62-8
cvgst1 protein, Culicoides variipennis sonorensis  EC 2.5.1.-   *Glutathione Transferase *Insect Proteins. Biochem Genet 2000 Dec:38(11-12):377-90
glutathione transferase M3-3  EC 2.5.1.18   *Glutathione Transferase Isoenzymes. Neurochem Res 2000 May;25(5):733-6
glutathione S-transferase T1  EC 2.5.1.-   *Glutathione Transferase. Pharmacogenetics 2000 Jun;10(4):301-9
glutathione S-transferase Mu 2  EC 2.5.1.18   *Glutathione Transferase. Biochem Biophys Res Commun 2000 Jul 21;274(1):32-6
GstE1 protein, Drosophila  EC 2.5.1.-   *Glutathione Transferase *Drosophila Proteins. Gene 2000 Apr 18;247(1-2):167-73
GSTZ1 protein, human  EC 2.5.1.-   *Glutathione Transferase. Pharmacogenetics 2000 Feb;10(1):49-57
microsomal glutathione S-transferase-I  EC 2.5.1.-   *Glutathione Transferase. Biochim Biophys Acta 1999 Sep 3;1446(3):389-96
glutathione S-transferase alpha  EC 2.5.1.18   *Glutathione Transferase *Isoenzymes. Jpn J Cancer Res 1999 May;90(5):530-5
GDAP protein  0   *Nerve Tissue Proteins Glycoproteins Glutathione Transferase Signal Transduction. J Neurochem 1999 May;72(5):1781-90
glutathione S-transferase M1  EC 2.5.1.18   *Glutathione Transferase. Blood 1999 Mar 1;93(5):1496-501
Gsto1 protein, mouse  0   *Carrier Proteins *Glutathione Transferase Heat-Shock Proteins. J Biol Chem 1999 Feb 19;274(8):5131-7
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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