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Glycosphingolipids

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Definition: Lipids containing at least one monosaccharide residue and either a sphingoid or a ceramide (CERAMIDES). They are subdivided into NEUTRAL GLYCOSPHINGOLIPIDS comprising monoglycosyl- and oligoglycosylsphingoids and monoglycosyl- and oligoglycosylceramides; and ACIDIC GLYCOSPHINGOLIPIDS which comprises sialosylglycosylsphingolipids (GANGLIOSIDES); SULFOGLYCOSPHINGOLIPIDS (formerly known as sulfatides), glycuronoglycosphingolipids, and phospho- and phosphonoglycosphingolipids. (From IUPAC's webpage)     
Examples Acidic Glycosphingolipids; Neutral Glycosphingolipids; Psychosine 		Other names Sphingoglycolipids; Asialogangliosides
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
flavuside B  0   *Glycosphingolipids. Chem Pharm Bull (Tokyo). 2011;59(9):1169-73
flavuside A  0   *Glycosphingolipids. Chem Pharm Bull (Tokyo). 2011;59(9):1169-73
neurosporaside  0   *Glycosphingolipids. J Nat Prod. 2011 Apr 25;74(4):554-8
panajaponin  0   *Glycosphingolipids. Nat Prod Res. 2010;24(1):86-91
(4-deoxyxylohexopyranosyl)-1-4-(1-fucopyranosyl-1-3)-(2-deoxy-2-acetamidoglucopyranosyl)-1-3-galactopyranosyl-1-4-glucopyranosyl-(1-1)-2-octadecanamido-4-octadecene-1,3-diol  0   *Glycosphingolipids. Glycoconj J 2008 May;25(4):335-44
(3-deoxyxylohexopyranosyl)-1-4-(1-fucopyranosyl-1-3)-(2-deoxy-2-acetamidoglucopyranosyl)-1-3-galactopyranosyl-1-4-glucopyranosyl-(1-1)-2-octadecanamido-4-octadecene-1,3-diol  0   *Glycosphingolipids. Glycoconj J 2008 May;25(4):335-44
rhizochalin D  0   *Glycosphingolipids. J Nat Prod 2007 Dec;70(12):1991-8
rhizochalin C  0   *Glycosphingolipids. J Nat Prod 2007 Dec;70(12):1991-8
9-O-methyl-(N-acetyl-alpha-D-neuraminosyl)-(2-3)-inositolphosphoceramide  0   *Glycosphingolipids. Chem Pharm Bull (Tokyo). 2007 Nov;55(11):1649-51
(2S,3S,4R)-1-O- (alpha-D-galactosyl)-2- tetracosanoylamino-1,3,4-nonanetriol  0   *Glycosphingolipids. J Org Chem. 2005 Mar 18;70(6):2398-401
rhizochalin A  0   *Glycosphingolipids. J Nat Prod 2005 Feb;68(2):255-7
catacerebroside C  0   *Glycosphingolipids. J Nat Prod 2003 Jul;66(7);1013-6
catacerebroside B  0   *Glycosphingolipids. J Nat Prod 2003 Jul;66(7);1013-6
catacerebroside A  0   *Glycosphingolipids. J Nat Prod 2003 Jul;66(7);1013-6
mannosylinositol phosphoylceramide  0   *Glycosphingolipids. J Biol Chem 2003 Nov 14;278(46):45049-55
inositolphosphorylceramide  0   *Glycosphingolipids. Arch Biochem Biophys 2003 Sep 15;417(2):219-26
HK1-ceramide 2  0   *Glycosphingolipids. Glycobiology 2002 Aug;12(8):517-22
lactotetraosylceramide  0   *Glycosphingolipids. J Biol Chem 2002 May 31;277(22):19709-19
1-(glucopyranosyl)-3-hydroxy-2-(2'-hydroxyheptadecanoyl)amino-9-methyl-4,8-octadecadiene  0   *Alkanes *Glycosphingolipids. Lipids 2001 May;36(5):521-7
glycosphingolipid GSL-3  0   *Glycosphingolipids. Eur J Biochem 2000 Mar;267(6):1837-46
sialyl 2-1 sphingosine  0   *Glycosphingolipids Sphingosine. Biochemistry 2000 Mar 14;39(10):2459-68
glycosphingolipid GSL-1  0   *Glycosphingolipids. J Membr Biol 1999 Feb 1;167(3):223-32
neurostatin  0   *Glycosphingolipids. Glia 1998 Jun;23(2):156-68
blood group A glycolipid A-6-2  0   *Glycosphingolipids. J Lipid Res 1998 Sep;39(9):1768-80
GSC 150  165621-51-2   *Glycosphingolipids. J Med Chem 1997 Jan 31;40(3):362-9
fucosyltetrahexosylceramide  0   *Glycosphingolipids. Eur J Biochem 1996 Aug 1;239(3):905-11
fucosylneolactonorhexaosylceramide  0   *Glycosphingolipids. J Biochem (Tokyo) 1996 Mar;119(3):456-62
PGL3b glycosphingolipid  0   *Glycosphingolipids. Biochim Biophys Acta 1995 Dec 7;1259(3):220-6
PGL3a glycosphingolipid  0   *Glycosphingolipids. Biochim Biophys Acta 1995 Dec 7;1259(3):220-6
sulfated Le(a) pentaosylceramide  0   *Glycosphingolipids Lewis Blood-Group System. Carbohydr Res 1995 Apr 30;270(2):C9-13
LPG2 protein, Leishmania  0   *Glycosphingolipids *Membrane Proteins *Protozoan Proteins.
1-O-(2-N-stearoylsphinganine-1-phosphoryl)-2-O-(mannopyranosyl)inositol  0   *Glycosphingolipids *Inositol Phosphates. Chem Phys Lipids 1995 Jun 19;76(2):225-40
3-sulfo-Le(x) pentaosylceramide  162635-35-0   *Glycosphingolipids Lewis Blood-Group System. Carbohydr Res 1994 Oct 17;263(2):C1-6
2,3-disulfo-Le(x) pentaosylceramide  162635-34-9   *Glycosphingolipids Lewis Blood-Group System. Carbohydr Res 1994 Oct 17;263(2):C1-6
mannosyl-1-4-(fucosyl-1-3)glucosyl-1-ceramide  0   *Glycosphingolipids Arthropods. Biochim Biophys Acta 1994 Nov 17;1215(1-2):163-9
ceramide trihexoside  0   *Glycosphingolipids. Intern Med 1994 Mar;33(3):172-6
KDN-neolactotetraosylceramide  0   *Glycosphingolipids. Carbohydr Res 1994 Jun 17;259(2):201-18
KDN-lactotetraosylceramide  0   *Glycosphingolipids. Carbohydr Res 1994 Jun 17;259(2):201-18
I-antigen  0   *Glycosphingolipids Antigens, Differentiation. Blood 1993 Jan 1;81(1):101-11
trifucosyl-Lewis-b antigen  139568-87-9   *Antigens, Neoplasm *Glycosphingolipids. Eur J Biochem 1992 Feb 1;203(3):577-86
mannose-bis(inositolphospho)ceramide  0   *Glycosphingolipids. J Cell Biol 1991;113(3):515
mannosylinositolphosphoceramide  0   *Glycosphingolipids. J Cell Biol 1991;113(3):515
stage-specific embryonic antigen-4  0   *Stage-Specific Embryonic Antigens Glycosphingolipids. Infect Immun 1990;58(12):4055
GL-Y  107874-00-0 Ceramide, 1-O-(O-6-deoxy-alpha-L-galactopyranosyl-(1-3)-O-(beta-D-galactopyranosyl-(1-4))-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-6)-O-(beta-D-galactopyranosyl-(1-3))-O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1-3)-O-alpha-D-galactopyr  *Glycosphingolipids. J Biochem (Tokyo) 1990;108(1):103
O-mannopyranosyl-(1-3)-O-xylopyranosyl-(1-2)-O-mannopyranosyl-(1-4)-O-glucopyranosyl-(1-1)-2-N-tetracosanoylsphingenine  128376-90-9   *Glycosphingolipids. Carbohydr Res 1990;195(2):199
O-mannopyranosyl-(1-3)-O-mannopyranosyl-(1-4)-O-glucopyranosyl-(1-1)-2-N-tetracosanoylsphingenine  128443-10-7   *Glycosphingolipids. Carbohydr Res 1990;195(2):199
difucosylneolactonorhexaosylceramide  90327-80-3   *Glycosphingolipids. Arch Biochem Biophys 1989;275(1):309
Y glycolipid  88161-63-1   *Glycosphingolipids Antigens. Biochem Biophys Res Commun 1988;151(1):100
stage-specific embryonic antigen-3  0   *Antigens, Tumor-Associated, Carbohydrate *Stage-Specific Embryonic Antigens Glycosphingolipids. J Biochem (Tokyo) 1987;101(3):563
2-aminoethylphosphonylglycosphingolipid  107371-10-8   *Glycosphingolipids. J Biochem (Tokyo) 1987;101(1):145
Le(y)-active trifucosylnonaosylceramide  104200-12-6   *Glycosphingolipids. J Biol Chem 1986;261(24):11247
diphosphonopentaosylceramide  103147-89-3   *Glycosphingolipids. J Biol Chem 1986;261(11):5138
sulfogangliotetraosylceramide IV(3)  99251-56-6   *Glycosphingolipids. J Biol Chem 1986;261(3):1440
ceramide heptassaccharide  97162-56-6   *Glycosphingolipids Membrane Lipids. J Biol Chem 1985;260(10):6410
sulfoglycolipid A  81406-48-6 Ganglioside GA2, 3B-(hydrogen sulfate)  *Glycosphingolipids. J Biol Chem 1982;257(3):1482
sulfoglycolipid P  80701-96-8 Ganglioside GA2, 3B,3C-bis(hydrogen sulfate)  *Glycosphingolipids. Biochem Biophys Res Commun 1981;103(3):1006
difucosyl heptaglycosylceramide  0   *Glycosphingolipids. J Biol Chem 1982;257(2):1079
Lipid III  0   *Glycosphingolipids. J Biol Chem 1981;256(21):10979
ceramide mono(2-aminoethylphosphono)pentaoside  0   *Glycosphingolipids. Neurosci Lett 1981;22(2):179
ceramide bis(2-aminoethylphosphono)pentaoside  0   *Glycosphingolipids. Neurosci Lett 1981;22(2):179
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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