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Gonanes

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Definition: Steroids containing the fundamental tetracyclic unit with no methyl groups at C-10 and C-13 and with no side chain at C-17. The concept includes both saturated and unsaturated derivatives.  includes gonenes, gonadienes, gonatrienes   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tetrazanbigen  0   *Azo Compounds *Gonanes. J Huazhong Univ Sci Technolog Med Sci. 2009 Jun;29(3):304-8
PX-866  0   *Gonanes. Mol Cancer Ther 2004 Jul;3(7):763-72
13-ethyl-15-hydroxygon-4-ene-3,17-dione  0   *Gonanes. J Steroid Biochem Mol Biol 1997 Mar;60(5-6):339-46
15,16-dihydro-6-methylcyclopenta(a)phenanthren-17-one  0   *Gonanes. Toxicol Lett 1995 Jan;75(1-3):93-100
RU 50331  136960-03-7 RU 50331  *Furans *Gonanes. J Steroid Biochem Mol Biol 1993 Apr;45(4):205-15
ZK 115716  120144-15-2   *Gonanes. J Chromatogr 1990;532(1):115
13-ethyl-3-methoxy-8,14-secogona-1,3,5(10),9(11)-tetraene-14,17-dione  62298-52-6   *Gonanes *Secosteroids. Indian J Exp Biol 1989;27(8):742
13-ethyl-gon-4-ene-3,17-dione  21800-83-9   *Gonanes. Yao Hsueh Hsueh Pao 1987;22(9):690
13-ethyl-17-hydroxy-gon-4-en-3-one  793-54-4   *Gonanes. Yao Hsueh Hsueh Pao 1987;22(9):690
15-methyl-8-aza-16-oxagona-1,3,5(10),13-tetraen-17-one  96554-86-8   *Gonanes *Steroids, Heterocyclic. Biokhimiia 1987;52(6):1037
onapristone  96346-61-1 Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(3-hydroxypropyl)-, (11beta,13alpha,17alpha)  *Gonanes.
Pharma Action Antineoplastic Agents ; Fertility Agents, Female ; Hormone Antagonists 		Contraception 1987;35(4):409
15,16-dihydro-1,11-methanocyclopenta(a)phenanthren-17-one  72041-34-0   *Gonanes. Carcinogenesis 1984;5(11):1485
15,16-dihydro-12-methylcyclopenta(a)phenanthren-17-one  789-46-8   *Gonanes. Carcinogenesis 1984;5(11):1395
homo-12,15-bisthia-1,3,5(10),6,8,13-gonahexaen-17-one  89207-21-6 Naphtho(2,1-d)thiopyrano(3,2-b)thiopyran-1(11H)-one, 2,3-dihydro  *Gonanes *Steroids, Heterocyclic. Steroids 1983;41(1):35
3,4,15,16-tetrahydro-3,4-dihydroxy-11-methyl-17H-cyclopenta(a)phenanthren-17-one  72007-69-3   *Gonanes. Carcinogenesis 1982;3(4):449
12,15-bisthia-1,3,5(10),6,8,13(14)-gonahexaen-17-one  78793-11-0 2H-Naphtho(2,1-d)thieno(3,2-b)thiopyran-1(10H)-one  *Gonanes *Steroids, Heterocyclic. Steroids 1981;37(4):353
cyclopentaphenanthrene  219-08-9   *Gonanes. Can Res 36(12):4525;1976
15,16-dihydrocyclopenta(a)phenanthren-17-one  786-66-3   *Gonanes. Arch Biochem Biophys 172(2):434;1976
15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one  892-17-1 15,16-dihydro-11-methyl-17H-cyclopenta(a)phenanthren-17-one  *Gonanes. Arch Biochem Biophys 172(2):434;1976; Biomed Mass Spectrom 4(1):48;1977; Br J Cancer 1979;40(6):914; Br J Cancer 28(1):84;1973; Cancer Res 1979;39(10):4160; Cancer Res 36(12):4387;1976
3-(3-oxo-17 beta-hydroxy-13-ethylgon-4-en-17 alpha-yl)propionic acid gamma-lactone  0   *Gonanes. J Pharm Soc Jpn 93(2):246;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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