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Graves Disease

More information in Books or onNLM PubMed
Definition: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).  GRAVES OPHTHALMOPATHY is also available   
Examples Graves Ophthalmopathy 		Other names Graves' Disease; Goiter, Exophthalmic; Exophthalmic Goiter; Basedow's Disease; Goiters, Exophthalmic; Exophthalmic Goiters; Disease, Graves'; Disease, Graves; Disease, Basedow's; Disease, Basedow; Basedows Disease; Basedow Disease
 
SubstanceCAS Registry & nameCategoriesSource
SLC25A16 protein, human  147571-37-7   *Autoantigens *Membrane Transport Proteins Graves Disease. DNA Seq 1992;3(2):71-81

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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