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Guaiacol

More information in Books or onNLM PubMed
Definition: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)     
Examples Guaifenesin 		Other names Catechol, Methyl; Methyl Catechol; 2-Methoxyphenol; 2-Methoxy-Phenol; 2-Hydroxyanisole; 2-Hydroxy-Anisole; Guaicol
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-methyl-2,6-dicarbomethoxyphenol  0   Guaiacol/*analogs & derivatives. J Phys Chem B. 2011 Oct 20;115(41):11840-51
aza-(6)-gingerol  0   *Amides Guaiacol/*analogs & derivatives. J Med Chem 2011 Sep 22;54(18):6295-304
bisvanillyl-hydralazone  0   Guaiacol/*analogs & derivatives Hydralazine/*analogs & derivatives. Antioxid Redox Signal 2011 Jun;14(11):2093-106
(10)-dehydrogingerdione  0   Guaiacol/*analogs & derivatives Cholesterol Ester Transfer Proteins/antagonists & inhibitors. Arch Pharm Res 2011 May;34(5):727-31
6-dehydrogingerdione  0   *Fatty Alcohols Guaiacol/*analogs & derivatives. Mol Nutr Food Res 2010 Sep;54(9):1307-17
CA 432  0   *Azetidines Guaiacol/*analogs & derivatives. J Pharmacol Exp Ther 2010 Nov;335(2):302-13
erythro-guaiacylglycerol-beta-ferulic acid ether  0   *Coumaric Acids Guaiacol/*analogs & derivatives. Beijing Da Xue Xue Bao. 2009 Apr 18;41(2):221-5
4-hydroxy-N-(3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl)-3-methoxybenzamide  0   *Imides Guaiacol/*analogs & derivatives. Arch Pharm Res 2010 Jan;33(1):67-70
(E)-2-((2-chlorobenzylimino)methyl)methoxyphenol  0   Guaiacol/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2009 Dec;74(5):1095-9
7,7'-oxodihydroguaiaretic acid  0   Guaiacol/*analogs & derivatives. Biosci Biotechnol Biochem 2008 Nov;72(11):2981-6
apocynol  0   Guaiacol/*analogs & derivatives. J Agric Food Chem 2000 Nov;48(11):5211-5
1,2,2-trithioeethyl ethylguaiacol  0   *Sulfides Guaiacol/*analogs & derivatives. Plant J 2008 Jan;53(2):368-79
1,4-dimethoxycatechol  0   *Guaiacol. J Org Chem 2007 Dec 21;72(26):9875-80
2-methoxy-4-vinylphenol  0   *Vinyl Compounds Guaiacol/*analogs & derivatives. J Agric Food Chem 1999 Dec;47(12):5169-72
3-hydroxy-4-methoxybenzaldehyde thiosemicarbazone  0   *Thiosemicarbazones Guaiacol/*analogs & derivatives. Appl Biochem Biotechnol 2007 Nov;143(2):101-14
2-(3-methoxy-4-hdyroxyphenyl)-3-hydroxymethyl-5-carboxyethylene-7-methoxy-2,3-dihydrobenzofuran  0   *Benzofurans Guaiacol/*analogs & derivatives. J Asian Nat Prod Res 2007 Apr-Aug;9(3-5):431-5
3-vanillyl propanol  0   *Butanols Guaiacol/*analogs & derivatives. Molecules 2007;12(8):1614-22
pinopalustrin  0   Guaiacol/*analogs & derivatives 4-Butyrolactone/*analogs & derivatives. Magn Reson Chem 2006 Jun;44(6):633-6
4-(3-hydroxymethyl-5-(3-hydroxypropyl)-2,3-dihydrobenzofuran-2-yl)-2-methoxyphenol  0   *Benzofurans Guaiacol/*analogs & derivatives. Magn Reson Chem 2006 Jun;44(6):633-6
1-(4-hydroxy-3-methoxyphenyl)-2-(4-(3-hydroxypropyl)-2-methoxyphenoxy)propane-1,3-diol  0   *Propylene Glycols Guaiacol/*analogs & derivatives. Magn Reson Chem 2006 Jun;44(6):633-6
4-chloro-N-(3-(3-(4-hydroxy-3-methoxyphenyl)acryloyl)phenyl)benzamide  0   *Benzamides Guaiacol/*analogs & derivatives P-Glycoprotein/antagonists & inhibitors. Biochem Biophys Res Commun 2007 Mar 30;355(1):136-42
4-chloroguaiacol  0   Guaiacol/*analogs & derivatives. J Hazard Mater 2006 Dec 1;138(3):614-9
N-(4-hydroxy-3,5-dimethoxyphenethyl)-3-(4-hydroxy-3-methoxyphenyl)acrylamide  0   *Acrylamides Guaiacol/*analogs & derivatives. Planta Med 2006 Aug;72(10):935-8
1-(4-(3-fluoropropoxy)-3-methoxyphenyl)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one  0   Guaiacol/*analogs & derivatives Fluorine Radioisotopes. J Med Chem 2006 Oct 5;49(20):6111-9
rourinoside  0   *Glycolipids Guaiacol/*analogs & derivatives. Phytochemistry 2006 Julu;67(13):1378-84
4-propylguaiacol  0   Guaiacol/*analogs & derivatives. J Agric Food Chem. 2006 Apr 19;54(8):3047-54
(Z)-2-(3-methoxybenzylidene)-1-azabicyclo(2.2.2)octan-3-one  0   *Quinuclidines Guaiacol/*analogs & derivatives. Acta Crystallogr C 2005 Nov;61(Pt 11):o660-1
4,8-bis(4-hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo(3.3.0)octane-2,6-dione  0   *Bicyclo Compounds, Heterocyclic Guaiacol/*analogs & derivatives. In Vivo 2005 Sep-Oct;19(5):849-53
2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo(2.2.2)octan-3-one  0   *Quinuclidines Guaiacol/*analogs & derivatives. Acta Crystallogr C 2003 Nov;59(Pt 11):o647-9
4-(1-ethoxy-1-(4-hydroxy-3-methoxy)benzyl)methyl-2-(4-hydroxy-3-methoxy)benzyl-3-hydroxymethyltetrahydrofuran  0   *Furans Guaiacol/*analogs & derivatives. Yao Xue Xue Bao 2003 Jul;38(7):520-2
8'-hydroxylariciresinol-4'-O-glucopyranoside  0   *Glucosides Guaiacol/*analogs & derivatives. Nat Prod Res 2003 Dec;17(6):381-7
10-hydroxyoleuropein  0   *Glucosides Guaiacol/*analogs & derivatives. Nat Prod Res 2003 Dec;17(6):381-7
gigantol  67884-30-4   Guaiacol/*analogs & derivatives. Zhongguo Zhong Yao Za Zhi 2002 Dec;27(12):919-23
scaphopetalone  0   *Tetrahydronaphthalenes Guaiacol/*analogs & derivatives. Phytochemistry 2003 Feb;62(4):647-50
1-hydroxy-2,5-diguaicyl-3,7-dioxabicyclo(3.3.0)octane  0   *Bicyclo Compounds, Heterocyclic Guaiacol/*analogs & derivatives. Phytochemistry 2002 Jan;59(1):85-90
2-(3-hydroxy-4-methoxyphenyl)-3-((3,4,5-trimethoxyphenyl)carbonyl)thiophene  0   *Thiophenes Guaiacol/*analogs & derivatives. Bioorg Med Chem Lett 2001 Sep 3;11(17):2341-3
2-(3-hydroxy-4-methoxyphenyl)-3-(3,4,5-trimethoxyphenyl)thiophene  0   *Thiophenes Guaiacol/*analogs & derivatives. Bioorg Med Chem Lett 2001 Sep 3;11(17):2341-3
tetrachloroguaiacol  0   Guaiacol/*analogs & derivatives. Aquat Toxicol 2001 Sep;54(1-2):143-8
tetraguaiacol  0   Guaiacol/*analogs & derivatives. Chemistry 2001 Jun 1;7(11):2449-58
6-paradol  27113-22-0   *Ketones Guaiacol/*analogs & derivatives Apoptosis. Cancer Res 2001 Feb 1;61(3):850-3
Shin Ruru A  0   *Acetaminophen *Caffeine *Guaiacol *Muramidase Drug Combinations Nonprescription Drugs. J Dermatol 2000 Jun;27(6):401-4
1,2-dihydroxy-1-(2',3'-dihydroxy-4'-methoxyphenyl)-2-(3'',4'',5''-trimethoxyphenyl)ethane  0   *Ethylene Glycols Guaiacol/*analogs & derivatives. J Nat Prod 2000 Jul;63(7):969-74
3,3'-dimethoxy-4,4'-dihydroxystilbene  0   *Stilbenes Guaiacol/*analogs & derivatives. Chung Kuo Chung Yao Tsa Chih 1997 Feb;22(2):106-8
2,2'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde  0   *Benzaldehydes Guaiacol/*analogs & derivatives. Acta Crystallogr C 1999 Jul 15;55( Pt 7):1176-9
XH-14  0   *Benzofurans Guaiacol/*analogs & derivatives Receptors, Purinergic P1. Bioorg Med Chem 1998 Sep;6(9):1517-24
mimosifoliol  0   *Acrylates Guaiacol/*analogs & derivatives. J Nat Prod 1996 Feb;59(2):190-2
graminone B  0   *Furans Guaiacol/*analogs & derivatives. J Nat Prod 1994 Dec;57(12):1734-6
solorinine  160098-90-8 Benzenebutanoic acid, alpha-(dimethylamino)-4-hydroxy-3,5-dimethoxy-, methyl ester, (+)  *Amino Acids Guaiacol/*analogs & derivatives. Phytochemistry 1994 Nov;37(4):1209-10
dehydroparadol  53172-10-4   Guaiacol/*analogs & derivatives. Res Comm Chem Pathol Pharmacol 1994 Apr;84(1):53-61
cinnamophilin  154677-96-0   *Lignans Guaiacol/*analogs & derivatives Thromboxane-A Synthase/antagonists & inhibitors. Br J Pharmacol 1994 Mar;111(3):906-12
4-ethylguaiacol  2785-89-9 Phenol, 4-ethyl-2-methoxy  Guaiacol/*analogs & derivatives. Pharmacology 1993 Nov;47(5):300-8
1-(4-hydroxy-3-methoxyphenyl)-2-propanone  2503-46-0   Acetone/*analogs & derivatives Guaiacol/*analogs & derivatives Flavoring Agents. Xenobiotica 1993 Jun;23(6):693-701
guaiacol-salsalate  0   *Salicylic Acids Guaiacol/*analogs & derivatives. Farmaco 1993 Jan;48(1):95-103
6-gingesulfonic acid  145937-21-9   *Sulfonic Acids Guaiacol/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1992 Aug;40(8):2239-41
4-fluoroguaiacol  450-93-1   Guaiacol/*analogs & derivatives. Int J Rad Appl Instrum (A) 1991;42(7):673
guaiacol salicylate  87-16-1   Aspirin/*analogs & derivatives Guaiacol/*analogs & derivatives. Yao Hsueh Hsueh Pao 1990;25(9):664
3,4,6-trichloroguaiacol  60712-44-9   Guaiacol/*analogs & derivatives. Ecotoxicol Environ Safety 1990;20(3):354
4,5,6-trichloroguaiacol  2668-24-8   Guaiacol/*analogs & derivatives. Ecotoxicol Environ Safety 1990;20(3):354
3,4,5-trichloroguaiacol  57057-83-7   Guaiacol/*analogs & derivatives. Ecotoxicol Environ Safety 1990;20(3):354
bromoform, codeine, sulfurgaicol, terpene drug combination  0   *Codeine *Guaiacol *Hydrocarbons, Brominated Drug Combinations. Rev Neurol (Paris) 1988;144(5):380
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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