encyclopedia of medical concepts
ψ 
ψ 
ψ 
ψ 

Proton-Translocating ATPases

More information in Books or onNLM PubMed
Definition: Multisubunit enzymes that reversibly synthesize ADENOSINE TRIPHOSPHATE. They are coupled to the transport of protons across a membrane.  GEN or unspecified; prefer specifics; do not confuse with H(+)-K(+)-TRANSPORTING ATPASE see H(+)-K(+)-EXCHANGING ATPASE; DF: H ATPASE   
Examples Bacterial Proton-Translocating ATPases; Chloroplast Proton-Translocating ATPases; H(+)-K(+)-Exchanging ATPase; Mitochondrial Proton-Translocating ATPases; Vacuolar Proton-Translocating ATPases 		Other names Proton-Translocating ATPase Complexes; Proton-Translocating ATPase Complex; Proton-Translocating ATPase; H(+)ATPase Complex; H(+)-Transporting ATPase; H(+)-Transporting ATP Synthase; F1 ATPase; F(1)F(0)-ATPase; Adenosinetriphosphatase F1; ATPase, F1; ATPase, F0; ATP Dependent Proton Translocase; Triphosphatase Complex, Adenosine; Proton Translocating ATPase, F1 Sector; Proton Translocating ATPase, F0 Sector; Proton Translocating ATPase Complexes; Proton Translocating ATPase Complex; Proton Translocating ATPase; H+ Translocating ATPase; F0 ATPase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ATP1 protein, Arabidopsis  EC 3.6.3.14   *Proton-Translocating ATPases *Arabidopsis Proteins Protein Subunits Mitochondrial Proteins. J Biol Chem 2011 Jun 17;286(24):21361-71
Atp8 protein, S cerevisiae  EC 3.6.3.14   *Proton-Translocating ATPases *Saccharomyces cerevisiae Proteins Protein Subunits. Proc Natl Acad Sci U S A 2009 Nov 3;106(44):18509-14
AHA7 protein, Arabidopsis  EC 3.6.3.14   *Proton-Translocating ATPases *Arabidopsis Proteins. New Phytol 2009;183(4):1072-84
AHA1 protein, Arabidopsis  EC 3.6.3.14. -   *Proton-Translocating ATPases *Arabidopsis Proteins. PLoS Biol. 2009 Jun 30;7(6):e1000139
SPAC29A4.19c protein, S pombe  EC 3.6.3.14   *Proton-Translocating ATPases *Schizosaccharomyces pombe Proteins. Genes Genet Syst 2008 Oct;83(5):373-81
YPK9 protein, S cerevisiae  EC 3.6.3.14   *Proton-Translocating ATPases *Saccharomyces cerevisiae Proteins. Nat Genet 2009 Mar;41(3):308-15
MON2 protein, human  EC 3.6.3.14   *Proton-Translocating ATPases. EMBO J 2008 May 21;27(10):1423-35
ATP6V0A2 protein, human  EC 3.6.3.14   *Proton-Translocating ATPases. Nat Genet 2008 Jan;40(1):32-4
CATP-1 protein, C elegans  EC 3.6.3.14   *Proton-Translocating ATPases *Caenorhabditis elegans Proteins. Development 2007 Mar;134(5):867-79
MAI-1 protein, C elegans  0   *Caenorhabditis elegans Proteins Proton-Translocating ATPases/antagonists & inhibitors. J Bioenerg Biomembr. 2006 Apr;38(2):93-9
ATP13A2 protein, human  EC 3.6.3.14   *Proton-Translocating ATPases. Nat Genet 2006 Oct;38(10):1184-91
ATP6AP2 protein, rat  EC 3.6.3.14   *Proton-Translocating ATPases *Receptors, Cell Surface. Hypertension 2006 Oct;48(4):549-51
ATP20 protein, S cerevisiae  EC 3.6.3.14   *Proton-Translocating ATPases *Saccharomyces cerevisiae Proteins. J Biol Chem 2005 Aug 12;280(32):29004-10
F0F1-ATPase epsilon subunit, E coli  EC 3.6.1.3   *Proton-Translocating ATPases *Escherichia coli Proteins Protein Subunits. J Biol Chem 2004 Aug 20;279(34):35616-21
Atp6v0a4 protein, mouse  EC 3.6.3.14   *Proton-Translocating ATPases.
PMP1 protein, S cerevisiae  0   *Proton-Translocating ATPases *Membrane Proteins *Proteolipids *Saccharomyces cerevisiae Proteins.
ATPAF2 protein, human  EC 3.6.3.14   *Proton-Translocating ATPases *Chaperonins.
AHA2 protein, Arabidopsis  EC 3.6.3.14   *Proton-Translocating ATPases *Arabidopsis Proteins. J Biol Chem 2003 Oct 24;278(43):42266-72
ATP2 protein, S cerevisiae  EC 3.6.3.14   *Proton-Translocating ATPases *Saccharomyces cerevisiae Proteins. EMBO J 2002 Dec 16;21(24):6893-904
HA2 protein, Trypanosoma cruzi  EC 3.6.1.-   *Proton-Translocating ATPases *Protozoan Proteins. J Biol Chem 2002 Nov 15;277(46):44497-506
HA1 protein, Trypanosoma cruzi  EC 3.6.1.-   *Proton-Translocating ATPases *Protozoan Proteins. J Biol Chem 2002 Nov 15;277(46):44497-506
gamma subunit, F(1) ATPase  EC 3.6.3.-   *Proton-Translocating ATPases Protein Subunits. J Biol Chem 2001 Dec 14;276(50):47227-32
AHA4 protein, Arabidopsis  EC 3.6.1.-   *Proton-Translocating ATPases *Arabidopsis Proteins. Plant J 2001 Aug;27(3):191-201
Atp6v0c protein, mouse  EC 3.6.3.14   *Proton-Translocating ATPases. Gene 2001 Aug 8;273(2):199-206
PMA2 protein, S cerevisiae  0   *Proton-Translocating ATPases *Saccharomyces cerevisiae Proteins.
Atp11 protein, S pombe  0   *Proton-Translocating ATPases *Molecular Chaperones *Schizosaccharomyces pombe Proteins.
Atp6v0a2 protein, mouse  0   *Proton-Translocating ATPases. J Biol Chem 2001 Jul 20;276(29):27519-26
PMA4 protein, Nicotiana plumbaginifolia  EC 3.6.3.6   *Proton-Translocating ATPases *Plant Proteins Membrane Proteins. J Biol Chem 2001 Mar 9;276(10):7017-22
citreoviral  0   *Furans Proton-Translocating ATPases/antagonists & inhibitors Mycotoxins. Org Lett 2000 Jan 27;2(2):223-6
PHI-1 protein, Nicotiana tabacum  EC 3.6.1.-   *Proton-Translocating ATPases *Plant Proteins. Plant Cell Physiol 1999 Jan;40(1):1-8
majastridin protein, Rhhodobacter blasticus  EC 3.6.1.-   *Bacterial Proteins *Proton-Translocating ATPases. J Mol Biol 1984 Oct 25;179(2):185-214
A1A0 ATPase, Methanosarcina mazei  EC 3.6.1.-   *Proton-Translocating ATPases *Archaeal Proteins. J Bacteriol 1998 Jul;180(13):3448-52
ATP6H protein, Bos taurus  EC 3.6.3.14   *Proton-Translocating ATPases. J Biol Chem 1998 May 1;273(18):10939-47
5-(5,6-dichloro-2-indolyl)-2--methoxy-N-(3-(4-(2-pyrimidinyl)piperazin-1-yl)propyl)-2,4-pentadienamide  0   *Indoles *Pyrimidines Proton-Translocating ATPases/antagonists & inhibitors. J Med Chem 1998 May 7;41(10):1568-73
5-(5,6-dichloro-2-indolyl)-2-methoxy-N-(8-methyl-8-azabicyclo(3.2.2)oct-3-yl)-2,4-pentadienamide  0   *Indoles *Bicyclo Compounds, Heterocyclic Proton-Translocating ATPases/antagonists & inhibitors. J Med Chem 1998 May 7;41(10):1568-73
ATP12 protein, S cerevisiae  EC 3.6.3.14   *Proton-Translocating ATPases *Molecular Chaperones *Saccharomyces cerevisiae Proteins. J Biol Chem 1998 Jan 30;273(5):2993-3002
papE protein, E coli  EC 3.6.3.14   *Proton-Translocating ATPases *Escherichia coli Proteins. Microb Pathog 1996 Jun;20(6):351-60
ZHA1 protein, Zostera marina  EC 3.6.1.35   *Proton-Translocating ATPases *Plant Proteins. Plant Physiol 1996 Jan;110(1):35-42
VMA-4 protein, Neurospora crassa  EC 3.6.3.14   *Fungal Proteins *Proton-Translocating ATPases Adenosine Triphosphatases. Biochim Biophys Acta 1995 Jul 6;1237(1):95-8
2-(3-methoxyphenylmethylthionyl)-imidazo(4,5-c)pyridine  0   *Imidazoles *Pyridines Proton-Translocating ATPases/antagonists & inhibitors. Bone Miner 1994 Nov;27(2):159-66
PMA1 protein, S cerevisiae  EC 3.6.1.-   *Proton-Translocating ATPases *Saccharomyces cerevisiae Proteins. Biochim Biophys Acta 1995 Mar 8;1234(1):127-32
invC protein, Salmonella typhimurium  EC 3.6.3.14   *Bacterial Proteins *Proton-Translocating ATPases. J Bacteriol 1994 Aug;176(15):4501-10
Bs1 protein, Zea mays  0   *Plant Proteins *Retroviridae Proteins Proton-Translocating ATPases. Plant Mol Biol 1994 May;25(2):137-40
VMA-3 protein, Neurospora crassa  EC 3.6.3.14   *Fungal Proteins *Proton-Translocating ATPases. Mol Gen Genet 1994 Apr;243(1):82-90
dibutyltin 3-hydroxyflavone  146816-94-6   *Flavonoids *Organotin Compounds Proton-Translocating ATPases/antagonists & inhibitors. Biochem Soc Trans 1993 Aug;21(Pt 3):253S
TFP1 protein, S cerevisiae  EC 3.6.3.14   *Proton-Translocating ATPases *Saccharomyces cerevisiae Proteins. Embo J 1993 Jun;12(6):2575-83
TFP3 protein, S cerevisiae  EC 3.6.3.14   *Proton-Translocating ATPases *Proteolipids *Saccharomyces cerevisiae Proteins. J Biol Chem 266(36):24526
i protein, E coli  0   *Escherichia coli Proteins Proton-Translocating ATPases. FEBS Lett 1991;292(1-2):145
fliI protein, bacteria  138414-68-3   *Bacterial Proteins *Proton-Translocating ATPases Flagella. J Bacteriol 1991;173(11):3564
rabeprazole  117976-90-6   *2-Pyridinylmethylsulfinylbenzimidazoles Adenosine Triphosphatases/antagonists & inhibitors Proton-Translocating ATPases/antagonists & inhibitors Stereoisomerism.
Pharma Action Anti-Ulcer Agents ; Enzyme Inhibitors 		Biochem Pharmacol 1990;39(4):661ACIPHEX; RABEPRAZOLE SODIUM; RABEPRAZOLE
bafilomycin A  116764-51-3 Bafilomycin A  *Macrolides Proton-Translocating ATPases/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Arzneimittelforschung 1988;38(8):1130
5'-(4-fluorosulfonylbenzoyl)inosine  83133-70-4   Inosine/*analogs & derivatives Proton-Translocating ATPases/antagonists & inhibitors. J Biol Chem 1986;261(30):14171
oligomycin B  11050-94-5   *Oligomycins Proton-Translocating ATPases/antagonists & inhibitors. J Dev Physiol 1986;8(1):67
adenosine 5'-monophosphate 2',3'-dialdehyde  13011-02-4   Adenosine Monophosphate/*analogs & derivatives Proton-Translocating ATPases/antagonists & inhibitors. FEBS Lett 1984;169(1):101
bafilomycin A1  88899-55-2   *Macrolides Proton-Translocating ATPases/antagonists & inhibitors.
Pharma Action Antifungal Agents ; Enzyme Inhibitors 		J Antibiot (Tokyo) 1984;37(2):110
concanamycin C  81552-34-3   *Macrolides Proton-Translocating ATPases/antagonists & inhibitors. J Antibiot (Tokyo) 1982;35(11):1618
concanamycin A  80890-47-7   *Macrolides Proton-Translocating ATPases/antagonists & inhibitors.
Pharma Action Antiviral Agents ; Enzyme Inhibitors
Triethyltin sulfate  57-52-3   *Triethyltin Compounds Proton-Translocating ATPases/antagonists & inhibitors. Mol Biochem Parasitol 1981;3(1):13
ATPase inhibitory protein  0   *Proteins Proton-Translocating ATPases Saccharomyces cerevisiae Proteins.
Pharma Action Enzyme Inhibitors 		Biochemistry 1980;19(13):2919; Biochemistry 1980;19(3):526; Biochim Biophys Acta 502(1):87;1978
3,3',4',5-tetrachlorosalicylanilide  1154-59-2   *Salicylanilides Allergens Proton-Translocating ATPases/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Acta Allergol 27(1):51;1972; Acta Derm Venerol 56:367;1976; Arch Biochem Biophys 178(2):368;1977; Arch Dermatol 113(10):1372;1977; Biochim Biophys Acta 555(2):337;1979; Contact Dermatol 1(4):263;1975; J Invest Dermatol 73(2):144;1979
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy