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Haloperidol

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Definition: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)     
Pharmacological Action Anti-Dyskinesia Agents; Antiemetics; Antipsychotic Agents; Dopamine Antagonists 		Other names HaldolDrugs* : HALOPERIDOL LACTATE; HALDOL SOLUTAB; HALDOL; HALOPERIDOL INTENSOL; HALOPERIDOL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butyl 4-phenylbutyrate  0   *Phenylbutyrates Haloperidol/*analogs & derivatives Receptors, sigma/antagonists & inhibitors. Eur J Med Chem 2011 Jan;46(1):433-8
sila-haloperidol  0   *Organosilicon Compounds Haloperidol/*analogs & derivatives. Drug Metab Dispos 2010 Jan;38(1):73-83
N-(4-tert-butylbenzyl)haloperidol  0   Haloperidol/*analogs & derivatives. Cell Physiol Biochem. 2009;23(4-6):295-304
4-(4-(4-chlorophenyl)-4-hydroxyazepan-1-yl)-1-(4-fluorophenyl)butan-1-one  0   *Azepines Haloperidol/*analogs & derivatives. J Med Chem 2004 Jan 29;47(3):497-508
N-n-butyl haloperidol iodide  0   Haloperidol/*analogs & derivatives. Acta Pharmacol Sin. 2003 Aug;24(8):757-63
dihydrohaloperidol  0   Haloperidol/*analogs & derivatives. Biol Pharm Bull 2001 Jun;24(6):612-7
4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine  52669-92-8   Haloperidol/*analogs & derivatives. Life Sci 1996;59(10):815-20
4-phenyl-1-(4-phenylbutyl)piperidine  136534-70-8   Haloperidol/*analogs & derivatives. Synapse 1995 May;20(1):85-90
thioketal haloperidol  150176-80-0   Haloperidol/*analogs & derivatives Ligands. J Comput Aided Mol Des 1995 Apr;9(2):113-30
4-(4-chlorophenyl)-1-(4-(4-fluoro-phenyl))-4-hydroxybutylpyridinium  0   *Pyridinium Compounds Haloperidol/*analogs & derivatives. Clin Pharmacol Ther 1994 Nov;56(5):512-20
N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium  125785-69-5   *Pyridinium Compounds Haloperidol/*analogs & derivatives. Pharmacol Biochem Behav 1993 Nov;46(3):739-44
bromperidol decanoate  75067-66-2   Haloperidol/*analogs & derivatives. Minerva Psichiatr 1992 Jan-Mar;33(1):51-5
metoclophen-modified nausea suppository  0   *Benztropine *Haloperidol *Lorazepam *Metoclopramide Drug Combinations. Am Pharm 1991;NS31(7):7
Metoclophen  0   *Benztropine *Dexamethasone *Haloperidol *Metoclopramide Drug Combinations. Am Pharm 1991;NS31(7):7
haloperidol 4-azidobenzoate  117345-85-4   *Azides Haloperidol/*analogs & derivatives. Biochem Biophys Res Commun 1988;155(2):930
haloperidol-succinylglycyliodotyrosine  113579-02-5   *Monoiodotyrosine Haloperidol/*analogs & derivatives Iodine Radioisotopes. FEBS Lett 1987;224 (2):267
iodoperidol  109852-09-7   Haloperidol/*analogs & derivatives. Int J Rad Appl Instrum (B) 1987;14(2):91
haloperidol hemisuccinate  87425-73-8   Haloperidol/*analogs & derivatives. Life Sci l986;38(20):1847
1-(3-(4-chlorobenzoyl)propyl)-4-hydroxy-4-(4-chlorophenyl)piperidine  59995-68-5   Haloperidol/*analogs & derivatives. Psychiatry Res 1984;11(3):259
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol  34104-67-1   Haloperidol/*analogs & derivatives. Psychiatry Res 1984;11(3):259
haloperidol decanoate  74050-97-8   Haloperidol/*analogs & derivatives.
Pharma Action Antipsychotic Agents 		Acta Psychiatr Belg 1981;81(4):399HALDOL; HALOPERIDOL DECANOATE
buzepide metiodide, haloperidol drug combination  0   *Azepines *Haloperidol Drug Combinations. J Urol Nephrol 84(9):676;1978
bromperidol  10457-90-6 4-(4-(4-bromophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone  Haloperidol/*analogs & derivatives.
Pharma Action Antipsychotic Agents 		Acta Psychiatr Belg 78(1):37-190;1978(16 articles); Arzneim Forsch 24(1):45;1974; Int Pharmacopsychiatry 12(1):20;1977; Int Pharmacopsychiatry 13(3):165;1978; J Med Chem 1980;23(1):75; Pharmakopsychiatry 11:81;1978; Pharmazie 32(12):764;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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