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Heterocyclic Compounds, 3-Ring

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Definition: A class of organic compounds containing three ring structures, one of which is made up of more than one kind of atom, usually carbon plus another atom. The heterocycle may be either aromatic or nonaromatic  GEN; prefer specifics; used for mapping supplementary chemicals   
Examples Acridines; Anthramycin; Carbazoles; Carbolines; Cinoxacin; Dactinomycin; Dibenzazepines; Dibenzothiazepines; Dibenzothiepins; Dibenzoxazepines; Dibenzoxepins; Flavins; Phenanthridines; Phenanthrolines; Phenazines; Phenothiazines; Psoralens; Quinpirole; Spectinomycin; Xanthenes 		Other names Heterocyclic Compounds, 3 Ring; Compounds, 3-Ring Heterocyclic; 3-Ring Heterocyclic Compounds; Heterocyclic Cpds, 3 Ring
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
melem  0   *Heterocyclic Compounds, 3-Ring *Triazines. Chemistry. 2012 Mar 12;18(11):3248-57
fatimahol  0   *Heterocyclic Compounds, 3-Ring *Phenols. Phytochemistry. 2011 Nov;72(16):2075-80
loloanolide B  0   *Cyclohexanones *Heterocyclic Compounds, 3-Ring. Org Lett. 2012 Jan 6;14(1):198-201
4-((1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl))-N-(8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)cyclohexylcarboxamide  0   *Heterocyclic Compounds, 3-Ring *Tetrahydronaphthalenes. J Med Chem. 2012 Jan 26;55(2):697-708.
N,N-dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo(4,5-d)pyrrolo(2,3b)pyridine-7-carboxamide  0   *Heterocyclic Compounds, 3-Ring Janus Kinase 2/antagonists & inhibitors. Leukemia. 2012 Feb;26(2):280-8.
8-fluoro-9-(4-methylpiperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid  0   *Heterocyclic Compounds, 3-Ring. AAPS PharmSciTech. 2011 Sep;12(3):872-8.
9-epi-sessilifoliamide J  0   *Heterocyclic Compounds, 3-Ring Alkaloids. Org Lett. 2011 Oct 7;13(19):5270-3
leucosceptroid D  0   *Heterocyclic Compounds, 3-Ring. J Org Chem. 2011 Aug 5;76(15):6169-76
leucosceptroid C  0   *Heterocyclic Compounds, 3-Ring. J Org Chem. 2011 Aug 5;76(15):6169-76
leucosceptroid B  0   *Heterocyclic Compounds, 3-Ring. J Org Chem. 2011 Aug 5;76(15):6169-76
5-2-(4-((ethylmethylamino)carbonyl)-3-fluorophenyl)-alpha,alpha-dimethyl-N-1,3,4-thiadiazol-2-yl-5H-(1)benzopyrano(2,3-b)pyridin-5-acetamide  0   *Heterocyclic Compounds, 3-Ring *Thiadiazoles. J Med Chem. 2011 Oct 27;54(20):7318-33.
2-(4-((dimethylamino)carbonyl)-3-fluorophenyl)-alpha,alpha-dimethyl-N-1,3,4-thiadiazol-2-yl-5H-(1)benzopyrano(2,3-b)pyridin-5-acetamide  0   *Heterocyclic Compounds, 3-Ring *Thiadiazoles. J Med Chem. 2011 Oct 27;54(20):7318-33.
GTx 134  0   *Heterocyclic Compounds, 3-Ring *Sulfones Receptor, IGF Type 1/antagonists & inhibitors. Clin Cancer Res. 2011 Jul 15;17(14):4693-704.
dolutegravir  0   *Heterocyclic Compounds, 3-Ring HIV Integrase Inhibitors. Antimicrob Agents Chemother 2010 Jan;54(1):254-8
integrastatin B  324518-09-4   *Heterocyclic Compounds, 3-Ring HIV Integrase Inhibitors. Org Biomol Chem. 2011 Aug 7;9(15):5354-7
integrastatin A  0   *Heterocyclic Compounds, 3-Ring HIV Integrase Inhibitors. Org Biomol Chem. 2011 Aug 7;9(15):5354-7
fluorescence probe NBzF  0   *Heterocyclic Compounds, 3-Ring *Nitro Compounds. J Am Chem Soc. 2011 Jul 13;133(27):10629-37
fluorescent probe Z1  0   *Heterocyclic Compounds, 3-Ring *Piperazines. Chem Commun (Camb). 2011 Aug 7;47(29):8301-3
3-chloro-8,9-dimethoxygeibalansine  0   *Heterocyclic Compounds, 3-Ring. Planta Med. 2011 Feb;77(3):271-6
1',2'-didehydro-7,8-dimethoxyplatydesmine  0   *Heterocyclic Compounds, 3-Ring *Quinolines. Planta Med. 2011 Feb;77(3):271-6
N-(2-(2-ethyl-8,9-dihydrofuro(3,2-c)pyrazolo(1,5-a)pyridin-1-yl)ethyl)acetamide  0   *Heterocyclic Compounds, 3-Ring Ligands. J Med Chem 2011 Jun 23;54(12):4207-18
BODIPY-PC  0   *Boron Compounds *Heterocyclic Compounds, 3-Ring. J Phys Chem B. 2011 May 19;115(19):6157-65
concentricolide  0   *Furans *Heterocyclic Compounds, 3-Ring. J Org Chem. 2011 May 20;76(10):4154-7
nitroaldol  0   *Heterocyclic Compounds, 3-Ring *Nitro Compounds. J Org Chem. 2011 May 20;76(10):3616-25
cnidilin  0   *Drugs, Chinese Herbal *Heterocyclic Compounds, 3-Ring. Fitoterapia. 2011 Apr;82(3):434-40
psilostachyin C  0   *Heterocyclic Compounds, 3-Ring *Pyrones. J Org Chem. 2011 May 6;76(9):3566-70
phyllostictine A  0   *Heterocyclic Compounds, 3-Ring Antibiotics, Antineoplastic. Toxicol Appl Pharmacol. 2011 Jul 1;254(1):8-17
sessilifoliamide C  0   *Heterocyclic Compounds, 3-Ring. Org Lett. 2011 May 20;13(10):2634-7
ferruginene A  0   *Heterocyclic Compounds, 3-Ring. J Nat Prod. 2011 Apr 25;74(4):712-7
ferruginene C  0   *Biphenyl Compounds *Heterocyclic Compounds, 3-Ring. J Nat Prod. 2011 Apr 25;74(4):712-7
ferruginene B  0   *Heterocyclic Compounds, 3-Ring. J Nat Prod. 2011 Apr 25;74(4):712-7
stemoninine  0   *Heterocyclic Compounds, 3-Ring Alkaloids. Biomed Chromatogr 2011 Apr;25(4):498-502
CDy2 compound  0   *Heterocyclic Compounds, 3-Ring *Piperidines. Angew Chem Int Ed Engl. 2011 Mar 14;50(12):2761-3
spiniferin-1  0   *Heterocyclic Compounds, 3-Ring. J Org Chem. 2011 Mar 4;76(5):1495-8
6-((1-hydroxynaphthalen-4-ylamino)dioxysulfone)-2H-naphtho(1,8-bc)thiophen-2-one  0   *Heterocyclic Compounds, 3-Ring *Sulfonamides. Bioorg Med Chem Lett 2011 Feb 1;21(3):1052-6
steperoxide D  0   *Heterocyclic Compounds, 3-Ring. Fitoterapia. 2010 Dec;81(8):1205-7
steperoxide C  0   *Heterocyclic Compounds, 3-Ring. Fitoterapia. 2010 Dec;81(8):1205-7
syntelin  0   *Heterocyclic Compounds, 3-Ring *Thioglycolates. Cell Res 2010 Decv;20(12):1386-9
LG 186  0   *Heterocyclic Compounds, 3-Ring *Hydrazones. Traffic 2010 Dec;11(12):1537-51
GSK2210875  0   *Heterocyclic Compounds, 3-Ring. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7521-4
fordianin B  0   *Heterocyclic Compounds, 3-Ring. Fitoterapia. 2009 Apr;80(3):173-6
1,4,7-trimethyloxatriquinane  0   *Heterocyclic Compounds, 3-Ring. J Am Chem Soc 2010 Aug 11;132(31):10662-4
4-(dimethylamino)-1-(4-(2-hydroxy-1-phenylethyl)amino-5,6,7,8-tetrahydropyrido(4',3'-4,5)thieno(2,3-d)pyrimidin-7-yl)-2-buten-1-one  0   *Heterocyclic Compounds, 3-Ring Receptor, Epidermal Growth Factor/antagonists & inhibitors. J Med Chem 2010 Oct 28;53(20):7316-26
1-(4-((2-hydroxy-1-phenylethyl)amino)-5,6,7,8-tetrahydropyrido(4',3'-4,5)thieno(2,3-d)pyrimidin-7-yl)-2-propen-1-one  0   *Heterocyclic Compounds, 3-Ring Receptor, Epidermal Growth Factor/antagonists & inhibitors. J Med Chem 2010 Oct 28;53(20):7316-26
byssochlamic acid bisdiimide  0   *Heterocyclic Compounds, 3-Ring *Imides. J Asian Nat Prod Res. 2010 Sep;12(9):809-13
5-bromo-3-oxa-4,11-diazatricyclo(6.2.1.0(2,6))undec-4-ene  0   *Heterocyclic Compounds, 3-Ring Ligands Receptors, Nicotinic. Bioorg Med Chem 2010 Jun 15;18(12):4498-508
3-bromo-5-oxa-4,10-diazatricyclo(6.3.1.0(2,6))dodec-3-ene  0   *Heterocyclic Compounds, 3-Ring Ligands Receptors, Nicotinic. Bioorg Med Chem 2010 Jun 15;18(12):4498-508
fonsecin B  0   *Heterocyclic Compounds, 3-Ring Ligands. Chem Commun (Camb). 2010 Jul 14;46(26):4680-2
N-(2-(6-(4-cyclobutylamino-5-trifluoromethylpyrimidine-2-ylamino)-1,2,3,4-tetrahydro-1,4-epiazano-naphthalen-9-yl)-2-oxo-ethyl)acetamide  0   *Heterocyclic Compounds, 3-Ring *Pyrimidines. Mol Cancer Ther 2010 Apr;9(4):883-94
VRX-413638  0   *Heterocyclic Compounds, 3-Ring. Angew Chem Int Ed Engl. 2010 Mar 1;49(10):1805-8
VRX-329747  0   *Heterocyclic Compounds, 3-Ring. Angew Chem Int Ed Engl. 2010 Mar 1;49(10):1805-8
4-azatricyclo(5.2.2.0(2,6))undecane-3,5,8-trione  0   *Heterocyclic Compounds, 3-Ring. Spectrochim Acta A Mol Biomol Spectrosc 2010 May;75(5):1559-65
marinnone A  0   *Heterocyclic Compounds, 3-Ring. Beijing Da Xue Xue Bao. 2009 Apr 18;41(2):221-5
marinnone B  0   *Heterocyclic Compounds, 3-Ring. Beijing Da Xue Xue Bao. 2009 Apr 18;41(2):221-5
2,10,11-triacetoxy-8-(3-methyltiopropanoyloxy)slov-3-enolide  0   *Heterocyclic Compounds, 3-Ring. Planta Med. 2010 Feb;76(3):284-90
thapsitranstagin  0   *Heterocyclic Compounds, 3-Ring. Planta Med. 2010 Feb;76(3):284-90
ammosamide C  0   *Heterocyclic Compounds, 3-Ring. J Am Chem Soc 2010 Mar 3;132(8):2528-9
N-(2-(phenyl)-8-methylpyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)phenylacetamide  0   *Acetamides *Heterocyclic Compounds, 3-Ring Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2010 Apr 22;53(8):3361-75
(R)-7-(2,4,5-trifluorophenyl)-5,6,7,8-tetrahydro-2,4b-diazafluoren-6-ylamine  0   *Heterocyclic Compounds, 3-Ring. J Org Chem. 2010 Mar 5;75(5):1343-53
MK 2206  0   *Heterocyclic Compounds, 3-Ring. Lancet Oncol 2010 Feb;11(2):103
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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