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Heterocyclic Compounds with 4 or More Rings

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Definition: A class of organic compounds containing four or more ring structures, one of which is made up of more than one kind of atom, usually carbon plus another atom. The heterocycle may be either aromatic or nonaromatic.  GEN; prefer specifics; used for mapping supplementary chemicals   
Examples Aporphines; Benzophenanthridines; Berberine Alkaloids; Cevanes; Dihydro-beta-Erythroidine; Ergolines; Ergotamines; Harringtonines; Morphinans; Pterocarpans; Rifamycins; Rotenone; Tetrapyrroles
Other names Heterocyclic Cpds, 4 or More Rings
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
brevianamide E  0   *Heterocyclic Compounds with 4 or More Rings *Indole Alkaloids. Org Lett. 2012 Jan 6;14(1):90-3
5,14-dioxo-12-(2-phenylalanine-N-ylethyl-1-yl)-1,2,3,5,5a,6,11,12,14,14a-decahydro-5H,14H-pyrolo(1,2-4,5)pyrazino(1,2-1,6)pyrido(3,4-b)indole  0   *Heterocyclic Compounds with 4 or More Rings Phenylalanine/*analogs & derivatives Urokinase-Type Plasminogen Activator/antagonists & inhibitors. ChemMedChem. 2011 Dec 9;6(12):2312-22.
6-chloro-10-(2-methanesulfonylmethylamino)-17-(4-methylpiperazin-1-yl)-19-methoxy-2,4,8,22-tetraazatetracyclo(14.3.1.13,7.19,13)docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaene  0   *Heterocyclic Compounds with 4 or More Rings. J Med Chem. 2012 Jan 12;55(1):449-64.
14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene  0   *Heterocyclic Compounds with 4 or More Rings Cyclin-Dependent Kinases/antagonists & inhibitors Janus Kinase 2/antagonists & inhibitors. J Med Chem. 2012 Jan 12;55(1):169-96.
kushecarpin A  0   *Heterocyclic Compounds with 4 or More Rings. Fitoterapia. 2011 Oct;82(7):1008-11
PF-4942847  0   *Heterocyclic Compounds with 4 or More Rings Antineoplastic Agents. Clin Cancer Res. 2011 Aug 15;17(16):5432-42
pyranocycloartobiloxanthone B  0   *Heterocyclic Compounds with 4 or More Rings *Xanthones. J Biomed Biotechnol. 2012;2012:130627.
diosbulbin B  20086-06-0   *Heterocyclic Compounds with 4 or More Rings. Hum Exp Toxicol. 2011 Sep;30(9):1333-41
chloranthalactone A  0   *Heterocyclic Compounds with 4 or More Rings *Lactones. Org Lett. 2011 Oct 7;13(19):5406-8
gymnodimine A  0   *Heterocyclic Compounds with 4 or More Rings *Imines Marine Toxins Nicotinic Antagonists. Org Biomol Chem. 2011 Dec 7;9(23):8112-8
1,16:6,7:8,9:14,15-tetranaphthoterrylene tetracarboxdiimide  0   *Heterocyclic Compounds with 4 or More Rings. Org Lett. 2011 Oct 21;13(20):5528-31
GSK1210151A  0   *Heterocyclic Compounds with 4 or More Rings. Nature. 2011 Oct 27;478(7370):529-33
PM 01183  0   *Carbolines *Heterocyclic Compounds with 4 or More Rings. Mol Cancer Ther. 2011 Aug;10(8):1481-9.
hirsutellone C  0   *Heterocyclic Compounds with 4 or More Rings. Org Lett. 2011 Oct 21;13(20); 5708-10
hirsutellone A  0   *Heterocyclic Compounds with 4 or More Rings. Org Lett. 2011 Oct 21;13(20); 5708-10
tricitinol B  0   *Benzopyrans *Heterocyclic Compounds with 4 or More Rings Topoisomerase II Inhibitors. J Med Chem. 2011 Aug 25;54(16):5796-810.
leuconicine B  0   *Heterocyclic Compounds with 4 or More Rings Alkaloids. Org Lett. 2011 Sep 2;13(17):4736-7
leuconicine A  0   *Heterocyclic Compounds with 4 or More Rings Alkaloids. Org Lett. 2011 Sep 2;13(17):4736-7
cassiarin F  0   *Heterocyclic Compounds with 4 or More Rings Alkaloids. Org Lett. 2011 Aug 19;13(16):4344-7
sparstolonin B  0   *Heterocyclic Compounds with 4 or More Rings. Biol Chem. 2011 Jul 29;286(30):26470-9
illicidione B  0   *Heterocyclic Compounds with 4 or More Rings. J Nat Prod. 2011 May 27;74(5):1268-71
illicidione A  0   *Heterocyclic Compounds with 4 or More Rings. J Nat Prod. 2011 May 27;74(5):1268-71
illicidione C  0   *Heterocyclic Compounds with 4 or More Rings. J Nat Prod. 2011 May 27;74(5):1268-71
SCH 1500022  0   *Cyclic S-Oxides *Heterocyclic Compounds with 4 or More Rings Amyloid Precursor Protein Secretases/antagonists & inhibitors. Biochemistry 2011 Jun 7;50(22):4973-80
10-(cyclohexylamino)-12-((2-hydroxyethyl)amino)-15-oxa-14-azatetracyclohexadeca-1(16),2,4,6,9,11,13-heptaen-8-one  0   *Heterocyclic Compounds with 4 or More Rings. J Med Chem 2011 May 12;54(9):3260-7
ent-homoabyssomicin B  0   *Heterocyclic Compounds with 4 or More Rings. Org Lett. 2011 May 6;13(9):2156-9
ent-homoabyssomicin A  0   *Heterocyclic Compounds with 4 or More Rings. Org Lett. 2011 May 6;13(9):2156-9
albiraminol A  0   *Heterocyclic Compounds with 4 or More Rings *Stilbenes. Chem Pharm Bull (Tokyo). 2011;59(4):452-7
vatalbinoside F  0   *Heterocyclic Compounds with 4 or More Rings *Stilbenes. Chem Pharm Bull (Tokyo). 2011;59(4):452-7
alstoscholarine  0   *Heterocyclic Compounds with 4 or More Rings *Indoles. Angew Chem Int Ed Engl. 2011 Apr 18;50(17):3954-7
alopecuridine  0   *Heterocyclic Compounds with 4 or More Rings. Angew Chem Int Ed Engl. 2011 Apr 18;50(17):3916-9
6-(2-(4-methoxyphenyl)ethyl)-9-((pyridine-3-ylmethyl)amino)pyrido(2',1'-2,3)imidazo(4,5-c)isoquinolin-5(6H)-one  0   *Heterocyclic Compounds with 4 or More Rings. Int J Cancer 2011 Jul 1;129(1):214-24
preussomerin BG1  0   *Heterocyclic Compounds with 4 or More Rings. J Org Chem. 2011 Mar 18;76(6):1821-30
pifithrin-beta  0   *Heterocyclic Compounds with 4 or More Rings Toluene/*analogs & derivatives Tumor Suppressor Protein p53/antagonists & inhibitors. Life Sci. 2011 Apr 25;88(17-18):774-83
seragakinone A  0   *Heterocyclic Compounds with 4 or More Rings. Angew Chem Int Ed Engl. 2011 Mar 1;50(10):2297-301
CORT 108297  0   *Aza Compounds *Heterocyclic Compounds with 4 or More Rings Receptors, Glucocorticoid/antagonists & inhibitors. Diabetes Obes Metab. 2010 Jun;12(6):545-7
oidiolactone D  0   *Heterocyclic Compounds with 4 or More Rings. Z Naturforsch C. 2011 Jan-Feb;66(1-2):31-4
TP 300  0   *Dipeptides *Heterocyclic Compounds with 4 or More Rings. Cancer Chemother Pharmacol 2010 Jan;65(2):363-71
5-O-desgalloylepipunicacortein A  0   *Heterocyclic Compounds with 4 or More Rings. Chem Commun (Camb). 2011 Feb 7;47(5):1628-30
complanadine E  0   *Heterocyclic Compounds with 4 or More Rings. Bioorg Med Chem. 2011 Jan 15;19(2):749-53
lyconadin D  0   *Heterocyclic Compounds with 4 or More Rings. Bioorg Med Chem. 2011 Jan 15;19(2):749-53
lyconadin E  0   *Heterocyclic Compounds with 4 or More Rings. Bioorg Med Chem. 2011 Jan 15;19(2):749-53
citridone A  0   *Heterocyclic Compounds with 4 or More Rings. Org Lett. 2011 Mar 4;13(5):1158-61
mahanimbine  0   *Carbazoles *Heterocyclic Compounds with 4 or More Rings Alkaloids. Fitoterapia. 2010 Dec;81(8):1129-33
vabicaserin  0   *Heterocyclic Compounds with 4 or More Rings Receptor, Serotonin, 5-HT2C. Drug Metab Dispos 2010 Apr;38(4):581-90
diazonamide B  0   *Heterocyclic Compounds with 4 or More Rings *Oxazoles. Org Lett. 2011 Feb 4;13(3):390-3
lecanopyrone  0   *Heterocyclic Compounds with 4 or More Rings. Z Naturforsch C. 2010 Nov-Dec;65(11-12):637-41
MRK-409  0   *Heterocyclic Compounds with 4 or More Rings *Hydrocarbons, Fluorinated Anti-Anxiety Agents. Curr Top Behav Neurosci. 2010;2():331-60
TPA-023-B  0   *Heterocyclic Compounds with 4 or More Rings *Hydrocarbons, Fluorinated Anti-Anxiety Agents. Curr Top Behav Neurosci. 2010;2():331-60
lamellarin R  0   *Heterocyclic Compounds with 4 or More Rings *Pyrroles. Org Lett. 2011 Jan 21;13(2):312-5
6-(4-methoxybenzyl)pyrido(2',1'-2,3)imidazo(4,5-c)isoquinolin-5(6H)-one  0   *Heterocyclic Compounds with 4 or More Rings. Invest New Drugs 2010 Dec;28(6):715-28
nobilisitine A  0   *Heterocyclic Compounds with 4 or More Rings Alkaloids. Org Lett. 2010 Nov 19;12(22):5210-3
purpurone  0   *Heterocyclic Compounds with 4 or More Rings *Pyrroles. Org Lett. 2010 Sep 17;12(18):4066-9
fordianin A  0   *Heterocyclic Compounds with 4 or More Rings. Fitoterapia. 2009 Apr;80(3):173-6
BMS 593214  0   *Heterocyclic Compounds with 4 or More Rings *Benzoic Acids Factor VIIa/antagonists & inhibitors. Thromb Haemost 2010 Aug 2;104(2):261-9
hopeachinol B  0   *Benzofurans *Heterocyclic Compounds with 4 or More Rings. Chemistry. 2010 Jun 1;16(21):6338-45
hopeachinol A  0   *Benzofurans *Heterocyclic Compounds with 4 or More Rings. Chemistry. 2010 Jun 1;16(21):6338-45
9alpha-hydroxy-7,11-dehydromatrine  0   *Heterocyclic Compounds with 4 or More Rings Alkaloids. Fitoterapia. 2010 Sep;81(6):524-7
N,N'-di((N-(3,6-di-t-butylcarbazyl))n-decyl)quinacridone  0   *Carbazoles *Heterocyclic Compounds with 4 or More Rings. Adv Mater 2010 Jul 6;22(25):2764-9
peroxysampsone B  0   *Heterocyclic Compounds with 4 or More Rings. Chem Biodivers 2010 Apr;7(4):953-8
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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