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Holothurin

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Definition: A highly toxic saponin occurring in HOLOTHUROIDEA. This marine toxin is an anionic surfactant, hemolyzing ERYTHROCYTES.  /antag permitted but consider also ANTITOXINS   
Pharmacological Action Cholinergic Agents; Poisons
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
holothurin A1  0   *Triterpenes Holothurin/*analogs & derivatives Antifungal Agents. Yao Xue Xue Bao. 2009 Jun;44(6):620-4
holothurin B4  0   Holothurin/*analogs & derivatives. J Nat Prod 2005 Apr;68(4):564-7
holothurin B3  0   Holothurin/*analogs & derivatives. J Nat Prod 2005 Apr;68(4):564-7
holothurin B2  0   Holothurin/*analogs & derivatives. J Nat Prod 2005 Apr;68(4):564-7
echinoside B  75410-52-5   Holothurin/*analogs & derivatives Sea Cucumbers. Chem Pharm Bull (Tokyo) 1985;33(12):5214
bivittoside D  77394-06-0   Holothurin/*analogs & derivatives Sea Cucumbers. Chem Biol Interact 1984;52(2):185
echinoside A  75410-53-6   Holothurin/*analogs & derivatives Sea Cucumbers. Chem Biol Interact 1984;52(2):185
holothurin C  70726-48-6   Holothurin/*analogs & derivatives. Antibiotiki 1982;27(4):276
holothurin B  11052-32-7   Holothurin/*analogs & derivatives. Antibiotiki 1982;27(4):276
holothurin A  38-26-6   Holothurin/*analogs & derivatives. Antibiotiki 1982;27(4):276
cucumarioside  74434-21-2   *Triterpenes Holothurin Sea Cucumbers. Biol Bull Acad Sci USSR 1980;7(3):217; Toxicon 12(3):327;1974
holotoxinogenin  23519-00-8 3 beta,20 epsilon,25-trihydroxy-16-oxolanost-9(11)- ene-18-carboxylic acid lactone  *Sapogenins Holothurin Sea Cucumbers. J Org Chem 40(4):466;1975
stichoposide  37341-37-0   *Glycosides *Triterpenes Holothurin Sea Cucumbers Toxins, Biological.
Pharma Action Radiation-Sensitizing Agents 		Comp Biochem Physiol 52(2):321;1975; Prikl Biokhim Mikrobiol 14(4):583;1978; Toxicon 10(3):299;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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