encyclopedia of medical concepts
ψ 

Hydrazones

More information in Books or onNLM PubMed
Definition: Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)  do not confuse with HYDRAZINES   
Examples Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1H-indole-3-carbaldehyde quinolin-8-yl-hydrazone  0   *Hydrazones *Quinolines. J Neuroimmunol. 2012 Mar;244(1-2):35-44.
CPSI-121  0   *Hydrazones. J Trauma Acute Care Surg. 2012 Feb;72(2):355-61.
RSVA405  0   *Aminophenols *Hydrazones AMP-Activated Protein Kinases. Mol Med. 2011 Sep-Oct;17(9-10):1022-30.
RSVA314  0   *Aminophenols *Hydrazones AMP-Activated Protein Kinases. Mol Med. 2011 Sep-Oct;17(9-10):1022-30.
O-hydroxyacetophenone-7-chloro-4-quinoline hydrazone  0   *Hydrazones *Quinolines. Molecules. 2011;16(10) (dup#14):8629-45
5-hydroxy-7,4'-diacetyloxyflavanone-N-phenyl hydrazone  0   *Hydrazones *Flavanones Antineoplastic Agents. J Agric Food Chem. 2011 Sep 28;59(18):10286-97
dyngo-4a  0   *Hydrazones *Naphthols Dynamins/antagonists & inhibitors. J Biol Chem. 2011 Oct 14;286(41):35966-76.
LS 081  0   *Hydrazones Niacinamide/*analogs & derivatives. J Exp Clin Cancer Res 2011;30:34
PZ 34 compound  0   *Hydrazones *Quinolines. PLoS One 2010;5(12):e15276
N-(4-nitrobenzylidene)-2-naphthohydrazide  0   *Hydrazones I-kappa B Kinase/antagonists & inhibitors. Eur J Med Chem 2011 Apr;46(4):1245-53
4-methylbenzaldehyde 2-naphthyloxyacetamidoacetohydrazone  0   *Hydrazones. Chem Biol Drug Des 2011 Mar;77(3):189-98
LG 186  0   *Heterocyclic Compounds, 3-Ring *Hydrazones. Traffic 2010 Dec;11(12):1537-51
YCG 063  0   *Hydrazones *Nitroimidazoles. Biochem Biophys Res Commun 2011 Jan 7;404(1):541-5
5-chloro-1H-indole-3-carboxaldehyde izonicotinoyl hydrazone  0   *Hydrazones *Indoles. Comb Chem High Throughput Screen. 2010 Aug;13(7):619-27
1-methylindole-3-carboxaldehyde izonicotinoyl hydrazone  0   *Hydrazones *Indoles. Comb Chem High Throughput Screen. 2010 Aug;13(7):619-27
N-(4-methylbenzylidenyl)-4'-(3'',4''-methylenedioxyphenyl)-6',7'- dimethoxyl-1'-hydroxyl-benzyl-2,3-dihydro-isoindol-1-hydrazone  0   *Hydrazones *Isoindoles. Chem Pharm Bull (Tokyo). 2010;58(10):1324-7
hesperetin-2-hydroxybenzoyl hydrazone  0   *Hydrazones Hesperidin/*analogs & derivatives. J Fluoresc 2010 Jul;20(4):891-905
4-hydroxy-N'-((2-hydroxyphenyl)methylidene)benzohydrazide  0   *Hydrazones Ligands. Talanta 2010 Sep 15;82(4):1385-91
DD-11 compound  0   *Hydrazones Dynamins/antagonists & inhibitors. Bioorg Med Chem Lett 2010 Aug 15;20(16):4858-64
DD-6 compound  0   *Hydrazones Dynamins/antagonists & inhibitors. Bioorg Med Chem Lett 2010 Aug 15;20(16):4858-64
oxalyl bis(3,4-dihydroxybenzylidene) hydrazone  0   *Benzyl Compounds *Hydrazones. Spectrochim Acta A Mol Biomol Spectrosc. 2010 Sep 15;77(1):297-303
2-((4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl)hydrazinylidene)propanedinitrile  0   *Hydrazones *Pyridazines. Int J Pharm 2010 Jul 15;394(1-2):18-25
2,5-hexanedione bis(isonicotinylhydrazone)  0   *Hydrazones. Spectrochim Acta A Mol Biomol Spectrosc 2010 May;75(5):1516-22
3-(2-(4-methylquinolin-2-yl)hydrazono)butan-2-one oxime  0   *Hydrazones *Oximes. Spectrochim Acta A Mol Biomol Spectrosc 2010 May;75(5):1446-51
MitoBloCK-1  0   *Hydrazones Thiourea/*analogs & derivatives. Proc Natl Acad Sci U S A 2010 May 25;107(21):9578-83
N-((2-(3,4-dimethoxybenzylidene)hydrazinyl)(imino)methyl)-3-(4-methoxyphenyl)acrylamide  0   *Acrylamides *Hydrazones. Bioorg Med Chem Lett 2010 Mar 1;20(5):1623-5
PIK 75  0   *Hydrazones *Sulfonamides Phosphatidylinositol 3-Kinases/antagonists & inhibitors. Am J Physiol Cell Physiol 2010 Apr;298(4):C929-41
3-carbaldehyde chromone-(benzoyl) hydrazone  0   *Chromones *Hydrazones. J Fluoresc. 2010 Jan;20(1):329-42
4,5-diazafluorene-9-p-nitrophenylhydrazone  0   *Aza Compounds *Hydrazones. Spectrochim Acta A Mol Biomol Spectrosc. 2010 Feb;75(2):753-9
1-(4-chlorophenylhydrazono)-1-(4-chlorophenylamino)-3,3-dimethyl-2-butanone  0   *Hydrazones. Mol Pharmacol 2010 Apr;77(4):704-13
SB-559457  0   *Hydrazones. Blood. 2010 Jan 7;115(1):89-93
salicylaldehyde-2-phenylquinoline-4-carboylhydrazone  0   *Hydrazones *Quinolines Ligands. Chem Pharm Bull (Tokyo). 2009 Nov;57(11):1237-42
6-ethoxychromone-3-carbaldehyde benzoyl hydrazone  0   *Chromones *Hydrazones. J Fluoresc 2009 Sep;19(5):847-56
7-nitro-1H-indole-2-carboxylic acid (4-(1-(guanidinohydrazone)ethyl)phenyl)amide  0   *Guanidines *Hydrazones. J Pharmacol Exp Ther 2009 Dec;331(3):816-26
salicylaldehyde rhodamine B hydrazone  0   *Hydrazones *Rhodamines. Spectrochim Acta A Mol Biomol Spectrosc 2009 Sep 15;74(1):265-70
2,6-dichlorobenzaldehydehydrazone  0   *Benzaldehydes *Hydrazones. Bioorg Med Chem. 2009 Sep 1;17(17):6158-65
2,4-dihydroxybenzaldehyde-4-nitrophenylhydrazone  0   *Benzaldehydes *Hydrazones. J Chem Phys. 2009 Apr 7;130(13):134708
3,4-dihydroxybenzaldehyde-4-nitrophenylhydrazone  0   *Benzaldehydes *Hydrazones. J Chem Phys. 2009 Apr 7;130(13):134708
7-methoxychromone-3-carbaldehyde-(4'-hydroxy)benzoyl hydrazone  0   *Chromones *Hydrazones Ligands. Eur J Med Chem 2009 Jun;44(6):2425-33
maxilon yellow 4GL  0   *Hydrazones *Pyridinium Compounds. J Hazard Mater 2009 Jun 15;165(1-3):1142-51
N-(6-((2-benzylidenehydrazinyl)carbonyl)-1,3-benzodioxol-5-yl)methanesulfonamide  0   *Hydrazones *Benzodioxoles. Bioorg Med Chem 2009 Feb 1;17(3):1125-31
di-2-pyridyl ketone 4-aminophenylhydrazone  0   *Hydrazones *Pyridines. Spectrochim Acta A Mol Biomol Spectrosc 2009 Feb;72(1):50-5
7-methoxychromone-3-carbaldehyde-benzoylhydrazone  0   *Chromones *Hydrazones Ligands. Chem Pharm Bull (Tokyo) 2009 Jan;57(1):69-73
OM 137  0   *Hydrazones *Thiazoles. Cancer Res 2009 Feb 15;69(4):1509-16
1,4-diformyl piperazine bis(carbohydrazone)  0   *Hydrazones *Piperazines. Spectrochim Acta A Mol Biomol Spectrosc. 2009 Jan;71(5):1712-9
N-2-hydroxy-4-methoxybenzaldehyde-N'-4-nitrobenzoyl hydrazone  0   *Hydrazones Ligands. Spectrochim Acta A Mol Biomol Spectrosc 2008 Dec 15;71(4):1253-60
cyclopentylidene-(4-(4'-chlorophenyl)thiazol-2-yl)hydrazone  0   *Hydrazones *Thiazoles. J Med Chem 2009 Jan 22;52(2):530-6
2-hydroxy-1-naphthylidene-N-cyanoacetohydrazone  0   *Hydrazones. Spectrochim Acta A Mol Biomol Spectrosc 2008 Nov 15;71(2):421-9
naringenin-2-hydroxy benzoyl hydrazone  0   *Hydrazones *Flavanones Ligands. Eur J Med Chem 2008 Aug;43(8):1688-95
dihydroxy benzoyl naphthyl hydrazone  0   *Hydrazones *Naphthalenes. J Recept Signal Transduct Res 2008;28(3):141-52
bis(2-hydroxyl-naphthalene-carboxaldehyde) benzil dihydrazone  0   *Hydrazones *Naphthalenes. Inorg Chem. 2008 Jun 16;47(12):5169-76
pyridine-2-acetaldehyde benzoylhydrazone  0   *Hydrazones *Pyridines. Anal Bioanal Chem. 2008 Jun;391(3):779-88
1H-pyrazole-3-carboxy-4-methyl-5-phenyl-(1H-indol-3-ylmethylene)hydrazide  0   *Hydrazones *Pyrazoles. ChemMedChem 2008 Jun;3(6):881-4
4,4'-dihydroxy-3,3'-dimethoxy-5,5'-biphenyl-1,1'-(diphthalazin-1-yl)methylhydrazone  0   *Hydrazones *Phthalazines. J Med Chem 2008 Jun 12;51(11):3171-81
phenylhydrazonopyrazolone sulfonate 1  0   *Benzenesulfonates *Hydrazones Protein Tyrosine Phosphatases/antagonists & inhibitors. Proc Natl Acad Sci U S A 2008 May 20;105(20):7275-80
benzophenone 4-aminobenzoylhydrazone  0   *Benzophenones *Hydrazones. J Colloid Interface Sci 2008 Apr 15;320(2):376-82
4-nitrobenzoic acid ((5-nitro-2-thiopheneyl)methylene)hydrazide  0   *Hydrazones *Thiophenes. Eur J Drug Metab Pharmacokinet 2007 Oct-Dec;32(4):197-203
rhodamine B 4-N,N-dimethylaminobenzaldehyde hydrazone  0   *Hydrazones *Rhodamines. Luminescence. 2008 Jan-Feb;23(1):28-31
methyl pyrazinylketone 4-aminobenzoyl hydrazone  0   *Hydrazones *Pyrazines. J Med Chem 2008 Jan 24;51(2):331-44
methyl pyrazinylketone 4-hydroxybenzoyl hydrazone  0   *Hydrazones *Pyrazines. J Med Chem 2008 Jan 24;51(2):331-44
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy