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Hydroxy Acids

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Definition: Organic compounds containing both the hydroxyl and carboxyl radicals.     
Examples Benzilates; Glycolates; Hydroxamic Acids; 3-Hydroxyanthranilic Acid; Hydroxybenzoic Acids; 3-Hydroxybutyric Acid; Lactates; Malates; Mandelic Acids; Mevalonic Acid; Mycolic Acids; Phosphoenolpyruvate; Quinic Acid; Shikimic Acid; Sugar Acids 		Other names Acids, Hydroxy
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(4-ethoyphenol)-2-hydroxy- acid amide  0   *Amides *Hydroxy Acids. Ai Zheng. 2003 Aug;22(8):790-4
8-hydroxytetradecadienoic acid  0   *Fatty Acids, Unsaturated *Hydroxy Acids. FEMS Microbiol Lett 2002 Mar 19;209(1):57-62
7,10,12-trihydroxy-8-octadecenoic acid  0   *Hydroxy Acids *Oleic Acids Pseudomonas aeruginosa. Curr Microbiol 2001 Sep;43(3):198-203
4-hydroxynonenoic acid  0   *Fatty Acids, Unsaturated *Hydroxy Acids. Toxicol Lett 2000 Apr 3;114(1-3):203-14
3-hydroxy-5,8-tetradecadienoic acid  0   *Fatty Acids, Unsaturated *Hydroxy Acids. Biochem Biophys Res Commun 1998 Dec 30;253(3):703-6
9,10,13-trihydroxy-11-octadecenoic acid  29907-57-1   *Hydroxy Acids *Oleic Acids. Z Naturforsch (C) 1995 Jan-Feb;98-104
BAY x 7195  0   *Hydroxy Acids. Eur J Clin Pharmacol 1994;47(3):227-30
4-hydroxy-2-nonenoic acid  0   *Hydroxy Acids. Arch Biochem Biophys 1995 Jan 10;316(1):197-205
29-hydroxytriacontanoic acid  0   *Fatty Acids *Hydroxy Acids. J Bacteriol 1994 Apr;176(8):2454-7
7-(7-((1,1'-biphenyl-4-yl)methyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl)-3,5-dihydroxy-6-heptenoic acid  153321-50-7   *Hydroxy Acids *Indazoles Hydroxymethylglutaryl CoA Reductases/antagonists & inhibitors. J Med Chem 1993 Nov 12;36(23):3674-85
7-(3-bromo-4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-pyrrol-1-yl)-3,5-dihydroxy-6-heptenoic acid methyl ester  151106-12-6   *Hydroxy Acids *Pyrroles Hydroxymethylglutaryl CoA Reductases/antagonists & inhibitors. J Med Chem 1993 Nov 12;36(23):3658-62
8,9,13-trihydroxydocosanoic acid  23066-89-9   *Hydroxy Acids. Lipids 1993 May;28(5):397-401
11-hydroxy-6,9,12-octadecatrienoic acid  145178-66-1   *Fatty Acids, Unsaturated *Hydroxy Acids. Biochem Biophys Res Commun 1992 Nov 16;188(3):1220-7
S 872419 A  0   *Hydroxy Acids. Eur J Opthalmol 1991 Jul-Sep;1(3):137-41
RP 62420  141267-40-5 6-Heptenoic acid, 7-(4-(4-fluorophenyl)-1,2-dihydro-2-(1-methylethyl)-1-oxo-3-isoquinolinyl)-3,5-dihydroxy-, (S-(R*,S*-(E)))  *Hydroxy Acids *Isoquinolines. J Chromatogr 1992 Mar 27;572(2):319-24
4-thioanisyl-2-biphenylyl-3-hydroxypropionic acid  141857-29-6   *Biphenyl Compounds *Hydroxy Acids. Pharmazie 1992 Mar;47(3):174-7
4-trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid  141901-74-8   *Biphenyl Compounds *Hydroxy Acids. Pharmazie 1992 Mar;47(3):174-7
2-hydroxy-2-trifluoromethyloctadec-4-enoic acid  135014-48-1   *Fatty Acids, Monounsaturated *Hydroxy Acids. Eur J Biochem 1991;199(1):153
4-hydroxy-4-phenylhexanamide  76425-98-4   *Amides *Hydroxy Acids. Arzneimittelforschung 1990;40(12):1289
3-hydroxy-3-phenylpentamide  131802-69-2   *Amides *Hydroxy Acids. Arzneimittelforschung1990;40(12):1289
3-hydroxy-7-octenoic acid  120676-01-9   *Fatty Acids, Monounsaturated *Hydroxy Acids. Int J Biol Macromol 1990;12(2):85
3-hydroxy-6-octenoic acid  128940-64-7   *Fatty Acids, Monounsaturated *Hydroxy Acids. Int J Biol Macromol 1990;12(2):85
2-hydroxydodecanedioic acid  74661-16-8 Dodecanedioic acid, 2-hydroxy  *Dicarboxylic Acids *Hydroxy Acids. Biomed Environ Mass Spectrom 1990;19(3):171
2-hydroxydocosanoic acid  13980-14-8 Docosanoic acid, 2-hydroxy  *Hydroxy Acids. Lipids 1989;24(1):89
2-hydroxytricosanoic acid  26632-12-2   *Hydroxy Acids. Lipids 1989;24(1):89
27-hydroxyoctacosanoic acid  121822-56-8   *Hydroxy Acids. J Biol Chem 1989;264(16):9300
9,12,13-trihydroxy-10-octadecenoic acid  29907-56-0   *Hydroxy Acids *Oleic Acids. Izv Akad Nauk SSSR (Biol) 1988;(6):932
11-hydroxy-4,7,9-hexadecatrienoic acid  112088-55-8   *Fatty Acids, Unsaturated *Hydroxy Acids. Biochemistry 1988;27(3):996
8-hydroxyhexadeca-4,6,10-trienoic acid  111916-07-5   *Fatty Acids, Unsaturated *Hydroxy Acids. Prostaglandins 1987;34(4):579
5-hydroxydecanoic acid  624-00-0   *Decanoic Acids *Hydroxy Acids.
Pharma Action Anti-Arrhythmia Agents 		Nippon Yakurigaku Zasshi 1987;89(3):155
2-hydroxysebacic acid  103963-71-9   *Decanoic Acids *Hydroxy Acids. Biomed Environ Mass Spectrom 1986;13(6):315
methyl-3-hydroxydodec-5-enoic acid  72864-23-4 Dodecanoic acid, 3-hydroxy-, methyl ester  *Hydroxy Acids. Eur J Biochem 1983;137(1-2):155
3-hydroxy-15-methylhexadecanoate  25491-28-5 hexadecanoic acid, 3-hydroxy-15-methyl  *Hydroxy Acids. J Bacteriol 1980;143(2):582
omega-hydroxyfatty acid:NADP oxidoreductase  EC 1.1.1.-   *Alcohol Oxidoreductases Hydroxy Acids. Arch Biochem Biophys 191(2):452;1978; Arch Biochem Biophys 191(2):466;1978
4-methyl-5-hydroxyvaleric acid  0   *Hydroxy Acids. Experientia 32(9):1138;1976
fatty acid ketols  0   *Hydroxy Acids *Keto Acids. Lipids 10(10):602;1975
vinylglycolic acid  600-17-9 2-hydroxy-3-butenoic acid  *Hydroxy Acids. J Bacteriol 127(1):671;1976; J Biol Chem 248(15):5456;1973; Proc Natl Acad Sci USA 71(12):5032;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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