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Hydroxybutyrates

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Definition: Salts and esters of hydroxybutyric acid.     
Examples Sodium Oxybate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(2-(4-((3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)amino)-5H-pyrrolo(3,2-d)pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide  0   *Hydroxybutyrates *Bicyclo Compounds, Heterocyclic Receptor, Epidermal Growth Factor/antagonists & inhibitors. J Med Chem. 2011 Dec 8;54(23):8030-50.
4-(1-(4-fluorobenzyl)-4-hydroxy-1H-indol-3-yl)-2-hydroxy-4-oxobut-2-enoic acid  0   *Hydroxybutyrates *Indoles. Antiviral Res. 2011 Oct;92(1):102-7.
6-tuliposide B  0   *Glucosides *Hydroxybutyrates. Phytochemistry 2010 Feb;71(2-3):312-24
hydroxy wilfordic acid  0   *Hydroxybutyrates Niacin/*analogs & derivatives. Arch Pharm Res 2009 Dec;32(12):1673-9
2-(1-(3-(4-(biphenyl-4-carbonyl)-2-propylphenoxy)propyl)-1,2,3,4-tetrahydroquinolin-5-yloxy)-2-methylpropionic acid  0   *Hydroxybutyrates *Quinolines PPAR gamma/agonists. J Med Chem 2009 Apr 23;52(8):2618-22
3-hydroxybutyrate methyl ester  0   *Hydroxybutyrates. Biomaterials. 2009 Mar;30(8):1532-41
3-Hydroxyisobutyric aciduria  0   *Amino Acid Metabolism, Inborn Errors Hydroxybutyrates/urine.
ethyl 4,4,4-trifluoro-3-hydroxybutanoate  0   *Hydroxybutyrates. Biotechnol J 2007 Feb;2(2):260-5
4-pyridyl-2-oxo-4-hydroxyisovaleric acid  0   *Hydroxybutyrates *Pyridines. Biochem Biophys Res Commun 2007 Sep 14;361(1):196-201
ethyl (2S,3S)-3-hydroxy-2-methylbutanoate  0   *Hydroxybutyrates. Acta Biol Hung. 2007 Jun;58(2):219-23
methyl alpha-hydroxyisobutyrate  0   *Hydroxybutyrates. Phys Chem Chem Phys 2006 Oct 14;8(38):4449-60
4-chloro-3-hydroxybutyric acid  0   *Hydroxybutyrates. J Biosci Bioeng 2006 Feb;101(2):97-103
3,6-(3-hydroxy-5-oxa-1,4-dioxo-6-phenyl-2-hexenyl)-4(1H)-quinolinone  0   *Hydroxybutyrates *Quinolones. J Med Chem 2006 Mar 23;49(6):1939-45
4-(1,3-dibenzyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl)-2-hydroxy-4-oxobut-2-enoic acid  0   *Hydroxybutyrates Uracil/*analogs & derivatives. J Med Chem 2006 Jan 26;49(2):445-7
2,3,4-trihydroxybutanamide  0   *Hydroxybutyrates. FEMS Immunol Med Microbiol 2005 Jul 1;45(1):71-4
(S)-(-)-4-(2-benzimidazolyl)-4-hydroxybutyric acid  0   *Benzimidazoles *Hydroxybutyrates. Basic Clin Pharmacol Toxicol. 2005 Apr;96(4):325-30
ethyl 3-hydroxy-2-oxobutanoate  0   *Hydroxybutyrates. Pest Manag Sci 2005 Apr;61(4):407-12
ethyl 3-methyl-3-hydroxy-2-oxobutanoate  0   *Hydroxybutyrates. Pest Manag Sci 2005 Apr;61(4):407-12
methyl-4-bromo-3-hydroxybutyrate  0   *Hydroxybutyrates. Appl Microbiol Biotechnol 2004 Nov;66(1):53-62
gamma-(4-methoxybenzyl)-gamma-hydroxybutyric acid  0   *Hydroxybutyrates. J Neurochem 2003 Nov;87(3):722-32
2-amino-4-(3'-hydroxyphenyl)-4-hydroxybutanoic acid  0   *Hydroxybutyrates *Phenylbutyrates. Bioorg Med Chem Lett 2002 Feb 11;12(3):361-3
ethyl 3-hydroxybutyrate  0   *Hydroxybutyrates Stereoisomerism. Biotechnol Bioeng 2001 Aug 5;74(3):256-63
poly(3-hydroxybutyrate-co-3-hydroxypropionate)  0   *Hydroxybutyrates *Polyesters. Int J Biol Macromol 2001 Mar 14;28(3):235-43
4-hydroxy-4-(3-pyridyl)butanoic acid  0   *Hydroxybutyrates *Pyridines. Chem Res Toxicol 1999 Feb;12(2):164-71
2,4-di-O-acetyl-3-deoxy-glycero-tetronic acid  0   *Hydroxybutyrates. Carbohydr Res 1998 Jan;306(1-2):163-70
4-hydroxybutyric acid  591-81-1   *Hydroxybutyrates.
phenytoin-bis-hydroxyisobutyrate  0   *Hydroxybutyrates Phenytoin/*analogs & derivatives. Pharm Res 1997 Feb;14(2):251-3
T 8581  0   *Hydroxybutyrates *Triazoles. Antimicrob Agents Chemother 1997 Jan;41(1):30-4
2-ethyl-2-hydroxybutyric acid  3639-21-2   *Hydroxybutyrates. Carcinogenesis 1994 Sep;15(9):1773-8
poly(3-hydroxybutanoate)  0   *Hydroxybutyrates *Polyesters. Eur J Biochem 1994 Sep 1;224(2):317-28
harzianic acid  157148-06-6   Hydroxybutyrates Pyrroles. J Antibiot (Tokyo) 1994 Jun;47(6):731-2
2,2-dimethyl-3-hydroxybutyric acid  29269-83-8   *Hydroxybutyrates. Eur J Drug Metab Pharmacokinet 1991 Jul-Sep;16(3):189-96
3-carboxy-5-methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide  134888-93-0   *Aniline Compounds *Hydroxybutyrates. J Med Chem 1992 Feb 7;35(3):507-10
A 771726  108605-62-5   *Aniline Compounds *Hydroxybutyrates.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Immunosuppressive Agents 		J Med Chem 1992 Feb 7;35(3):507-10
poly(3-hydroxybutyrate-co-4-hydroxybutyrate)  117068-64-1   *Hydroxybutyrates *Polyesters. Int J Biol Macromol 1990;12(2):106
technetium Tc 99m 2-hydroxyisobutyric acid  0   *Hydroxybutyrates *Organotechnetium Compounds. Int J Rad Appl Instrum (A) 1990;41(2):221
technetium Tc 99m 2-ethyl-2-hydroxybutyric acid  0   *Hydroxybutyrates *Organotechnetium Compounds. Int J Rad Appl Instrum (A) 1990;41(2):221
thrazarine  120128-14-5   Hydroxybutyrates Serine/analogs & derivatives. J Antibiot (Tokyo) 1988;41(11):1568
acetyl acetonate  17272-66-1 2,4-Pentanedione, ion(1-)  *Hydroxybutyrates *Pentanones Allergens. Contact Dermatitis 1986;14(4):263
3,4-dihydroxybutanoic acid  1518-61-2   *Hydroxybutyrates. Am J Physiol 1984;246(4 pt 2):R542
3-hydroxy-3-cyclohexylbutyric acid  17692-20-5   *Hydroxybutyrates. J Med Chem 1983;26(12):1764
4-arsono-2-hydroxybutanoic acid  86880-38-8 Butanoic acid, 4-arsono-2-hydroxy-, (+-)  *Arsenic *Hydroxybutyrates. Biochem J 1983;123(1):211
4-hydroxy-2-butenoic acid  4013-24-5 2-Butenoic acid, 4-hydroxy  *Hydroxybutyrates. J Chromatogr 1982;230(1):1
2-hydroxybutyric acid  565-70-8   *Hydroxybutyrates. Fed Proc 1981;40(10):2511
alpha-aceto-alpha-hydroxybutyrate  3142-65-2   *Hydroxybutyrates. Anal Biochem 1980;105(1):101
butoctamide hydrogen succinate  32838-28-1   *Amides *Hydroxybutyrates. Psychopharmacology 1980;70(2):117
beta-hydroxy-alpha-ketobutyric acid  1944-42-9 butanoic acid, 3-hydroxy-2-oxo  *Hydroxybutyrates. Biochim Biophs Acta 1980;630(1):92
lithium hydroxybutyrate  61742-10-7 hydroxybutanoic acid, monolithium salt  *Hydroxybutyrates *Organometallic Compounds Lithium. Biul Eksp Biol Med 88(11):574;1979
3-hydroxyisobutyric acid  2068-83-9 3-hydroxy-2-methylpropanoic acid  *Hydroxybutyrates. Biochim Biophys Acta 585(4):643;1979
2-methyl-3-hydroxybutyric acid  473-86-9   *Hydroxybutyrates. Biomed Mass Spectrom 5(3):198;1978
pantoic acid  470-29-1 (R)-2,4-dihydroxy-3,3-dimethylbutanoic acid  *Hydroxybutyrates. Ukr Biokhim Zh 49(6):34;1977
4-hydroxy-3-oxobutyrate  0   *Hydroxybutyrates. Biochem Med 17(3):284;1977
butoctamide  32838-26-9 N-(2-ethylhexyl)-3-hydroxybutyramide  *Amides *Hydroxybutyrates. Biochem Pharm 26(3):197;1977
4-(p-biphenylyl)-3-hydroxybutyric acid  6845-17-6 (1,1'-biphenyl)-4-butanoic acid, beta-hydroxy  *Hydroxybutyrates. Br J Clin Pharmacol 3(3):513;1976; Farmaco [Sci] 32(8):622;1977
2-hydroxy-4-phosphonobutyric acid  51360-19-1   *Hydroxybutyrates. J Biochem 155(2):440;1976
4-(4-(2'-fluorobiphenylyl))-4-hydroxycrotonic acid  34682-15-0 4-(2'-fluoro(1,1'-biphenyl)-4-yl)-4-hydroxy-2-butenoic acid  *Hydroxybutyrates. Arzneim Forsch 25(12):1947;1975
phenyl-gamma-methylmercapto-alpha-hydroxybutyrate  52703-97-6 Butanoic acid, 2-hydroxy-4-(methylthio)-, phenyl ester  *Hydroxybutyrates. J Pharm Sci 63(5):751;1974
2-hydroxyisobutyric acid  594-61-6 2-hydroxy-2-methylpropanoic acid  *Hydroxybutyrates. Arch Dermatol 110(4):586;1974
poly-beta-hydroxybutyrate  26063-00-3   *Hydroxybutyrates *Polyesters. Biochem J 123(4):29P;1971; Z Tierphysiol 38(1):13;1977
2-hydroxy-3-butynoic acid  40027-75-6   *Hydroxybutyrates. Biochemistry 14(17):3903;1975; Biochemistry 15(9):1791;1976; Biochemistry 1979;18(21):4724; Biochemistry 1979;18(21):4733; J Biol Chem 247(24):7858;1972
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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