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Hydroxychloroquine

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Definition: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)     
Pharmacological Action Antimalarials; Antirheumatic Agents; Enzyme Inhibitors 		Other names Hydroxychloroquine Sulfate (1:1) Salt; Hydroxychloroquine Sulfate; Plaquenil; Oxychloroquine; Oxychlorochin; HydroxychlorochinDrugs* : HYDROXYCHLOROQUINE SULFATE; PLAQUENIL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
desethylhydroxychloroquine  4298-15-1   Hydroxychloroquine/*analogs & derivatives. J Chromatogr 1986;377:454

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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