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17-alpha-Hydroxypregnenolone

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Definition: A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of biosynthesis of GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.      Other names 17alpha Hydroxypregnenolone; 17 alpha Hydroxypregnenolone; 17 Hydroxypregnenolone; Hydroxypregnenolone; 17alpha-Hydroxypregnenolone; 17-Hydroxypregnenolone, (3beta,17alpha)-Isomer; 17-Hydroxypregnenolone, (3beta,13alpha,17alpha)-Is; 17-Hydroxypregnenolone, (3beta,13alpha)-Isomer; 17-Hydroxypregnenolone, (3alpha)-Isomer; 17-Hydroxypregnenolone; 17 alpha-Hydroxypregnenolone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7-hydroxypregnenolone  0   17-alpha-Hydroxypregnenolone/*analogs & derivatives. Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17282-7
17-hydroxy-pregnenolone-3-oxyacetyl-biotine  0   *17-alpha-Hydroxypregnenolone. Steroids 2001 Feb;66(2):81-6
17-hydroxy-pregenolone-3-hemisuccinate-histamine  0   *17-alpha-Hydroxypregnenolone *Succinates. Steroids 2001 Feb;66(2):81-6
3,15-dihydroxy-5-pregnen-20-one  32746-93-3   17-alpha-Hydroxypregnenolone/*analogs & derivatives. J Steroid Biochem Mol Biol 1994 Jun;49(2-3):213-26
21-hydroxypregnenolone  1164-98-3   *17-alpha-Hydroxypregnenolone Isomerism. J Steroid Biochem 1987;26(3):337
17-hydroxypregnenolone sulfate  28901-70-4   17-alpha-Hydroxypregnenolone/*analogs & derivatives. J Clin Endocrinol Metab 1981;46(5):721
3 beta,15 beta,17 alpha-trihydroxy-5-pregnen-20-one  80380-40-1 Pregn-5-en-20-one, 3,15,17-trihydroxy-, (3beta,15beta)  17-alpha-Hydroxypregnenolone/*analogs & derivatives. J Steroid Biochem 1981;14(9):901
3 beta,21-diacetoxy-5-pregnen-20-one  1693-63-6 Pregn-5-en-20-one, 3,21-bis(acetyloxy)-, (3beta)  17-alpha-Hydroxypregnenolone/*analogs & derivatives. Steroids 1980;36(5):575
19-hydroxypregnenolone 3-methyl ether  58994-45-9 Pregn-5-en-20-one, 19-hydroxy-3-methoxy-, (3beta)  17-alpha-Hydroxypregnenolone/*analogs & derivatives Isomerism. J Steroid Biochem 6(11):1505;1975
19-hydroxypregnenolone 3-acetate  26360-40-7 3-(acetyloxy)-19-hydroxypregn-5-en-20-one  17-alpha-Hydroxypregnenolone/*analogs & derivatives Isomerism. J Steroid Biochem 6(11):1505;1975
3 beta,16 alpha-dihydroxypregn-5-en-20-one  520-88-7   *17-alpha-Hydroxypregnenolone Isomerism. Ateneo Parmense 48(4):353;1977
17, 21-dihydroxypregnenolone  1167-48-2 3 beta,17,21-trihydroxypregn-5-en-20-one  17-alpha-Hydroxypregnenolone/*analogs & derivatives. Probl Endokrinol 23(5):92;1977
16 alpha-hydroxypregnenolone 7-(O-carboxymethyl)oxime  61192-54-9 Acetic acid, ((((3beta,16alpha)-3,16-dihydroxy-20-oxopregn-5-en-7-ylidene)amino)oxy)  17-alpha-Hydroxypregnenolone/*analogs & derivatives. J Steroid Biochem 7(9):697;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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