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Hydroxyprogesterones

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Definition: Metabolites or derivatives of PROGESTERONE with hydroxyl group substitution at various sites.     
Examples 17-alpha-Hydroxyprogesterone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1alpha,3beta-dihydroxy-5beta-pregn-16-en-20-one-3-O-beta-D-glucopyranoside  0   *Glucosides *Hydroxyprogesterones. Zhongguo Zhong Yao Za Zhi 2008 Oct;33(20):2347-50
4-pregnen-20,21-diol-3-one  0   *Hydroxyprogesterones. J Enzyme Inhib Med Chem 2007 Oct;22(5):570-6
17alpha-hydroxy-6-methylene-progesterone  0   *Hydroxyprogesterones. Eksp Klin Farmakol. 2006 Jul-Aug;69(4):36-8
16,17-epoxy-3-hydroxypregn-5-en-20-one  0   *Hydroxyprogesterones. Chem Commun (Camb) 2002 Sep 21;(18):2102-3
3-O-glucopyranosyl-3,15-dihydroxypregn-5-en-20-one  0   *Glycosides *Hydroxyprogesterones. Planta Med 2001 Apr;67(3):270-3
Injectable No. 1  0   *Hydroxyprogesterones Estradiol/*analogs & derivatives. Contraception 1995 Mar;51(3):167-83
progesterone 11-hemisuccinate-(2-iodohistamine)  69436-84-6   *Hydroxyprogesterones Histamine/*analogs & derivatives Iodine Radioisotopes. J Neurochem 1994 Oct;63(4):1434-8
7-hydroxyprogesterone  27534-93-6   *Hydroxyprogesterones. J Steroid Biochem Mol Biol 1991;38(2):249
17-hydroxypregn-4-ene-3-one  3090-78-6   *Hydroxyprogesterones. Gen Comp Endocrinol 1990;80(2):223
11,14-dihydroxypregn-4-ene-3,20-dione  95832-17-0   *Hydroxyprogesterones. Steroids 1990;55(1):17
7,14-dihydroxypregn-4-ene-3,20-dione  640-30-2   *Hydroxyprogesterones. Steroids 1990;55(1):17
11-hydroxyprogesterone 11-glucuronide  129238-72-8   *Hydroxyprogesterones. J Steroid Biochem 1989;33(3):423
19-hydroxyprogesterone  596-63-4   *Hydroxyprogesterones. J Steroid Biochem 1988;31(44):475
14-hydroxyprogesterone  16031-66-6   *Hydroxyprogesterones. J Med Chem 1987;30(8):1502
6-hydroxy-6-methyl-17-acetoxyprogesterone  984-46-3   *Hydroxyprogesterones. Yao Hsueh Hsueh Pao 1986;21(8):613
6,17,20-trihydroxypregn-4-ene-3-one  105248-42-8   *Hydroxyprogesterones. Biochem J 1986;239(2):473
6-hydroxyprogesterone  604-20-6   *Hydroxyprogesterones. Gen Comp Endocrinol 1986;61(2):214
progesterone 11-glucuronide-alkaline phosphatase conjugate  0   *Alkaline Phosphatase *Hydroxyprogesterones. J Reprod Fertil 1986;76(1):375
14-hydroxypregna-1,4-diene-3,20-dione  97055-11-3   *Hydroxyprogesterones. J Steroid Biochem 1985;22(3):399
15-hydroxyprogesterone  600-72-6   *Hydroxyprogesterones. Experientia 1985;41(4):516
18-hydroxyprogesterone  596-69-0   *Hydroxyprogesterones. J Med Chem 1985;28(2):233
15,17-dihydroxyprogesterone  71118-02-0 Pregn-4-ene-3,20-dione, 15,17-dihydroxy-, (15beta)  *Hydroxyprogesterones. Steroids 1984;43(2):153
pregna-1,4-diene-11-ol-3,20-dione  4224-37-7   *Hydroxyprogesterones. Experientia 1983;39(6):617
thymine-hydroxyprogesterone  87536-00-3 2,4(1H,3H)-Pyrimidinedione, 1-(17-hydroxy-3,20-dioxopregn-4-en-21-yl)-5-methyl  *Hydroxyprogesterones Thymine/*analogs & derivatives. J Steroid Biochem 1983;18(6):673
trophobolen  87533-94-6 Pregn-4-ene-3,20-dione, 17-((1-oxoheptyl)oxy)-, mixt. with (17beta)-estra-1,3,5(10),triene-3,17-diyl 3-propanoate 17-(3-pyridinecarboxylate) and (17beta)-17-((1-oxododecyl)oxy)estr-4-en-3-one  *Hydroxyprogesterones Drug Combinations Estradiol/*analogs & derivatives Nandrolone/*analogs & derivatives. Exp Neurol 1983;80(2):279
17-hydroxyprogesterone heptanoate  4596-16-1   *Hydroxyprogesterones. Exp Neurol 1983;80(2):279
21-amino-17-hydroxyprogesterone  84869-30-7 Pregn-4-ene-3,20-dione, 21-amino-17-hydroxy-, hydrochloride  *Hydroxyprogesterones. Steroids 1982;40(4):393
12 alpha-hydroxyprogesterone  19897-02-0   *Hydroxyprogesterones. Endokrynol Pol 1981;32(2):185
21-bromoacetoxyprogesterone  36049-51-1 Pregn-4-ene-3,20-dione, 21-((bromoacetyl)oxy)  *Hydroxyprogesterones. Endocrinology 1981;109(2):670
progesterone 11-hemisuccinate  62624-72-0   *Hydroxyprogesterones Antigens. J Steroid Biochem 1981;14(4):405
11-hydroxyprogesterone  312-90-3 pregn-4-ene-3,20-dione, 11-hydroxy  *Hydroxyprogesterones.
Pharma Action Progestins 		J Chromatogr 1981;222(3):475
6 beta-acetoxyprogesterone  1675-95-2 Pregn-4-ene-3,20-dione, 6-(acetyloxy)-, (6 beta)  *Hydroxyprogesterones. Steroids 1980;35(1):111
7 beta-carboxymethyl-17-hydroxyprogesterone  0   *Hydroxyprogesterones. Steroids 1980;35(1):65
7 alpha-carboxymethyl-17-hydroxyprogesterone  0   *Hydroxyprogesterones. Steroids 1980;35(1):65
17-(bromoacetoxy)progesterone  61886-11-1 Pregn-4-ene-3,20-dione, 17-((bromoacetyl)oxy)  *Hydroxyprogesterones. Biochemistry 1980;19(5):978
17 alpha,20 beta-dihydroxypregn-4-en-3-one  1662-06-2 (20R)-17,20-dihydroxypregn-4-en-3-one  *Hydroxyprogesterones. Comptes Rend 283(10):1205;1976; Gen Comp Endocrinol 34:149;1978; J Reprod Fertil 56(2):465;1979; J Steroid Biochem 6:345;1975
17-alpha-hydroxy-progesterone caproate  630-56-8 17-((1-oxohexyl)oxy)pregn-4-ene-3,20-dione  *Hydroxyprogesterones Antineoplastic Agents Delayed-Action Preparations Progesterone Congeners.
Pharma Action Estradiol Antagonists ; Progestins 		Endokrinologie 73(1):33;1979; Ther Umsch 36(6):516;1979; Vopr Onkol 1979;25(10):53DELALUTIN; HYDROXYPROGESTERONE CAPROATE; MAKENA
16-hydroxyprogesterone  14264-44-9 16 alpha-hydroxypregn-4-ene-3,20-dione  *Hydroxyprogesterones. Clin Biochem 8(6):369;1975
caprovestrol  75919-66-3 Caprovestrol  *Estradiol *Hydroxyprogesterones Drug Combinations Delayed-Action Preparations. Vopr Okhr Materin Det 21(5):72;1976
16 alpha,17 alpha-isopropylidenedioxyprogesterone  4968-09-6 16,17-((1-methylethylidene)bis(oxy))(16 delta alpha)- pregn-4-ene-3,20-dione  *Hydroxyprogesterones. Probl Endokrinol (Mosk) 23(1):101;1977
16-methylene-17 alpha-hydroxyprogesterone  3965-17-1 Pregn-4-ene-3,20-dione, 17-hydroxy-16-methylene  *Hydroxyprogesterones. Pharmazie 30(8):506;1975
16-methylene-17 alpha-acetoxyprogesterone  6815-51-6   *Hydroxyprogesterones. Pharmazie 30(8):509;1975
2-bromoacetoxyprogesterone  55092-30-3   *Hydroxyprogesterones. J Biol Chem 250(19):7656;1975
17-acetoxy-11-oxaprogesterone  57170-48-6   *Hydroxyprogesterones *Steroids, Heterocyclic. Steroids 25(6):781;1975
methylene-dehydroacetoxy-progesterone  805-84-5 17-hydroxy-16-methylene-delta 6-progesterone-17- acetate  *Hydroxyprogesterones Progesterone Congeners. Hormones Brain Function WL 300/601h:143;1971; Physiol Bohemoslov 21(4):647;1972
flumedroxone  15687-21-5 17- acetyloxy-6 alpha-(trifluoromethyl)preg-4-ene,3,20-dione  *Hydroxyprogesterones Migraine Disorders/drug therapy. Acta Pharm Suec 15(3):233;1978
17,20-dihydroxy-4-pregnen-3-one  10456-50-5 17 alpha,20 alpha-dihydroxy-4-pregnen-3-one  *Hydroxyprogesterones. Gen Comp Endocrinol 34:6;1978; J Endocrinol 61(3):401;1974; J Endocrinol 65(3):41P;1975; J Endocrinol 66(1):61;1975; J Endocrinol 67:89;1975; J Endocrinol 69(3):433;1976
17-hydroxyprogesterone 17-(9-oxo-10-chlorodecanoate)  40946-49-4 Pregn-4-ene-3,20-dione, 17-((10-chloro-1,9-dioxodecyl)oxy)  *Hydroxyprogesterones. Steroids 22(1):139;1973
6-bromoacetoxyprogesterone  0   *Hydroxyprogesterones. J Biol Chem 248(16):5641;1973; Steroids 27(6):741;1976
11 alpha-bromoacetoxyprogesterone  36049-50-0   *Hydroxyprogesterones. J Biol Chem 248(16):5641;1973; J Biol Chem 250(19):7656;1975
17-acetoxy-7-oxaprogesterone  42061-81-4   *Hydroxyprogesterones *Steroids, Heterocyclic. J Med Chem 16(6):647;1973
6-trifluoromethyl-16-methylene-17 alpha-hydroxy-4,6- pregnadiene-3,20-dione 17-acetate  35463-52-6 17-(acetyloxy)-16-methylene-6-(trifluoromethyl)pregna-4,6-diene-3,20-dione  *Hydroxyprogesterones. J Med Chem 15(6):679;1972
primosiston  37218-07-8   *Estradiol *Hydroxyprogesterones Drug Combinations.
17 alpha-acetoxy-2',2',6 beta-trifluoro-6 beta,7 beta- dihydro-16-methylenecyclopropa(6,7)progesterone  40129-31-5 3'H-Cyclopropa(6,7)pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-3',3',6-trifluoro-6,7-dihydro-16-methylene-, (6beta,7beta)  *Hydroxyprogesterones. J Chem Soc (Perkin I) 3:227;1973
16 alpha-bromoacetoxyprogesterone  51541-48-1   *Hydroxyprogesterones. Biol Reprod 11:519;1974; J Biol Chem 247(11):3424;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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