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Hypersensitivity

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Definition: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.  IM; use qualif with caution; /drug ther: consider also ANTI-ALLERGIC AGENTS; atopic   
See Also Anti-Allergic Agents; Desensitization, Immunologic; Multiple Chemical Sensitivity
Examples Drug Hypersensitivity; Environmental Illness; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immune Complex Diseases; Latex Hypersensitivity; Wissler's Syndrome
Other names Allergy; Allergic Reaction; Reactions, Allergic; Reaction, Allergic; Hypersensitivities; Allergies; Allergic Reactions
 
SubstanceCAS Registry & nameCategoriesSource
SK&F 84210  68981-32-8   *Aniline Compounds *Pyrones Hypersensitivity/drug therapy Ophthalmic Solutions. J Med Chem 1991;34(1):392
6-(dimethylamino)-N-(1H-tetrazol-5-yl)-2-pyrazinecarboxamide  111374-19-7   *Pyrazines *Tetrazoles Hypersensitivity/drug effects. Chem Pharm Bull (Tokyo) 1990;38(5):1250
HSR 6071  111374-21-1 Pyrazinecarboxamide, 6-(1-pyrrolidinyl)-N-1H-tetrazol-5-yl  *Pyrrolidines *Tetrazoles Hypersensitivity/drug effects Passive Cutaneous Anaphylaxis/drug effects. Jpn J Pharmacol 1990;52(1):87
CI 949  121530-58-3   *Indoles *Tetrazoles Hypersensitivity/drug effects. Agents Actions 1989;27(3-4):303
4-(2-oxo-3-(1H-tetrazol-5-yl)-2H-chromen-8-yloxy)butyric acid  103876-49-9   *Chromones *Tetrazoles Hypersensitivity/drug effects. Jpn J Pharmacol 1989;50(2):111
AHR 5333  60284-71-1   *Piperidines Hypersensitivity/drug therapy. Int Arch Allergy Appl Immunol 1988;85(4):428
N-(4-(1,4-benzodioxan-6-yl)-2-thiazolyl)oxamic acid  74604-77-6   *Thiazoles Hypersensitivity/drug therapy. J Med Chem 1983;26(8):1158
isamoxole  57067-46-6 Propanamide, N-butyl-2-methyl-N-(4-methyl-2-oxazolyl)  *Oxazoles Hypersensitivity/drug therapy. Biomed Mass Spectrom 5(7):466;1978; Xenobiotica 1979;9(10):585
doxantrazole  51762-95-9   *Thioxanthenes Xanthones Asthma/drug therapy Hypersensitivity/drug therapy.
Pharma Action Bronchodilator Agents ; Phosphodiesterase Inhibitors
Acta Allergolog 31:471;1976; Annals Allergy 40(1):25;1978; Br J Pharm 59(3):473P;1977; Br Med J 1(6156):92;1979; Br Med J 3(5978):283;1975; Eur J Clin Pharm 11(2):107;1977; Int Arch Allerg Appl Immunol 56:39;1978; Int Arch Allergy Appl Immunol 1980;61(1):75; J Chromatogr 115(1):93;1975; J Invest Dermatol 71(4):266;1978; J Membrane Biol 39:57;1978; J Pharm Pharmacol 1979;31(11):730; J Pharmkinet Biopharm 6(6):521;1978; Lancet 1(7917):1169;1975; Lancet 1(8015):809;1977; Life Sci 18(2):153;1976; Tubercle 56(2):172;1975
2-carboxy-7-methoxyxanthen-9-one  33510-07-5 9H-xanthene-2-carboxylic acid, 7-methoxy-9-oxo  *Xanthones Hypersensitivity/drug therapy. Int Arch Allergy Appl Immunol 45(5):708;1973
AH 7725  33459-28-8 9H-xanthene-2-carboxylic acid, 7-(2-hydroxyethoxy)-9-oxo  *Xanthones Hypersensitivity/drug therapy. Int Arch Allergy Appl Immunol 45(1):84;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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