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Hypoglycemic Agents

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Definition: Substances which lower blood glucose levels.  note entry term HYPOGLYCEMIC EFFECT: use only for the hypoglycemic effect of a chemical substance   
Examples Dipeptidyl-Peptidase IV Inhibitors 		Other names Antidiabetics; Effects, Hypoglycemic; Effect, Hypoglycemic; Drugs, Hypoglycemic; Drugs, Antidiabetic; Agents, Hypoglycemic; Agents, Antihyperglycemic; Agents, Antidiabetic; Hypoglycemics; Hypoglycemic Effects; Hypoglycemic Effect; Antihyperglycemics; Antihyperglycemic Agents; Hypoglycemic Drugs; Antidiabetic Drugs; Antidiabetic Agents
Substances having this pharmacologic action: methyl 2-tetradecylglycidate; 2-bromopalmitate; inositol phosphate glycan; meglitinide; copper bis(3,5-diisopropylsalicylate); AICA ribonucleotide; midaglizole; ethyl 2-(5-(4-chlorophenyl)pentyl)oxiran-2-carboxylate; vanadyl sulfate; gusperimus; BRL 26830A; ciglitazone; diphenyleneiodonium; glucuronyl glucosamine glycan sulfate; phenyl biguanide; Acarbose; Insulin, Long-Acting; Biphasic Insulins; Insulin, Short-Acting; Insulin Aspart; Insulin Lispro; Insulin, Regular, Pork; Insulin, Lente; Insulin, Ultralente; glargine; allicin; alliin; Chlorpropamide; Tolazamide; Tolbutamide; Metformin; Glyburide; Gliclazide; Glipizide; Acetohexamide; Phenformin; Buformin; Butoxamine; Insulin; Insulin, Isophane; Carbutamide; gliquidone; 2-tetradecylglycidic acid; insulin glulisine; isophane insulin, insulin lispro drug combination 50:50; insulin aspart, insulin aspart protamine drug combination 30:70; insulin, pork; isophane insulin, pork drug combination 30:70; insulin, regular, beef-pork; Insulin, Globin Zinc; isophane insulin, beef; isophane insulin, beef-pork; isophane insulin, pork; insulin, protamine zinc, beef-pork; voglibose; pramlintide; mitiglinide; rosiglitazone; 2,4-thiazolidinedione; zopolrestat; peroxovanadate; repaglinide; glibornuride; exenatide; CL 316243; nateglinide; pioglitazone; englitazone; etomoxir; fenugreek seed meal; glimepiride; troglitazone; ponalrestat; miglitol; emeriamine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-O-lactoylborapetoside B  0   *Diterpenes Hypoglycemic Agents. J Nat Prod. 2012 Feb 24;75(2):153-9
6'-O-lactoylborapetoside B  0   *Diterpenes Hypoglycemic Agents. J Nat Prod. 2012 Feb 24;75(2):153-9
2-((3-(aminomethyl)-2-(2-methylpropyl)-1-oxo-4-phenyl-1,2-dihydroisoquinolin-6-yl)oxy)acetamide  0   *Isoquinolines Hypoglycemic Agents Dipeptidyl-Peptidase IV Inhibitors. Bioorg Med Chem. 2011 Aug 15;19(16):4953-70
1-((2-adamantyl)amino)acetyl-2-cyano-(S)-pyrrolidine, monohydrochloride  0   *Nitriles *Pyrrolidines Adamantane/*analogs & derivatives Hypoglycemic Agents Dipeptidyl-Peptidase IV Inhibitors. J Pharmacol Exp Ther. 2012 Jan;340(1):64-72
(2R,3R,4S,5S,6R)-2-(5-chloro-4-(4-ethylbenzyl)thiophen-2-yl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol  0   *Thiophenes Hypoglycemic Agents. Bioorg Med Chem. 2011 Oct 1;19(19):5813-32
(S)-4'-((5-(1-(4-bromophenyl)ethylcarbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid  0   *Biphenyl Compounds Hypoglycemic Agents. Nature. 2011 Sep 22;477(7365):477-81
(S)-4'-((5-((1-(4-nitrophenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid  0   *Biphenyl Compounds Hypoglycemic Agents. Nature. 2011 Sep 22;477(7365):477-81
bacosine  0   *Triterpenes Hypoglycemic Agents. Planta Med. 2011 May;77(8):804-8
balaglitazone  0   *Quinazolines *Thiazolidinediones Hypoglycemic Agents. J Chromatogr A. 2004 Sep 17;1049(1-2):183-87
1-(((3-hydroxy-1-adamantyl)amino)acetyl)-2-cyanopyrrolidine  0   *Pyrrolidines Adamantane/*analogs & derivatives Hypoglycemic Agents Glucagon-Like Peptide 1. J Med Chem 2003 Jun 19;46(13):2774-89
cogent db  0   *Plant Preparations Hypoglycemic Agents Medicine, Ayurvedic. Comp Biochem Physiol C Toxicol Pharmacol 2002 Jan;131(1):19-25
3-(1,1'-biphenyl)-4-yl-N,N-dimethyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-4-acetamide  0   *Pyrazoles Hypoglycemic Agents. J Med Chem 2001 Aug 2;44(16):2601-11
cerasee tea  0   *Plant Extracts *Momordica charantia Diabetes Mellitus Hypoglycemic Agents. Diabetes Res 1985;2(2):81

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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