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Ibogaine

More information in Books or onNLM PubMed
Definition: One of several indole alkaloids extracted from Tabernanthe iboga, Baill. It has a complex pharmacological profile, and interacts with multiple systems of neurotransmission. Ibogaine has psychoactive properties and appears to modulate tolerance to opiates.     
Pharmacological Action Excitatory Amino Acid Antagonists; Hallucinogens 		Other names 12-Methoxyibogamine; NIH10567; NIH 10567; 12 Methoxyibogamine; NIH-10567; Endabuse
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
technetium 99m tricarbonyl ibogaine  0   *Organotechnetium Compounds Ibogaine/*analogs & derivatives. J Pharm Sci 2009 Dec;98(12):4650-60
20-desethyl-20-hydroxymethyl-11-demethoxyibogaine  0   Ibogaine/*analogs & derivatives. Nat Prod Res 2006 Jul 10;20(8):758-65
2-methoxyethyl 18-methoxycoronaridinate  0   Ibogaine/*analogs & derivatives. J Med Chem 2003 Jun 19;46(13):2716-30
18-hydroxycoronaridine  0   Ibogaine/*analogs & derivatives. Drug Metab Dispos 2002 Jun;30(6):663-9
18-methoxycoronaridine  0   Ibogaine/*analogs & derivatives. Brain Res 1996 May 6;719(1-2):29-35
noribogaine  0   Ibogaine/*analogs & derivatives. Brain Res 1995 Mar 27;675(1-2):342-4
heyneanine hydroxy-indolenine  80151-98-0   Ibogaine/*analogs & derivatives. J Nat Prod 1988;51(3):528
voacristine  545-84-6   Ibogaine/*analogs & derivatives. Mutat Res 1986;171(1):17
tabernanthine  83-94-3 13-methoxyibogamine  *Ibogaine Isomerism. Naunyn Schmiedebergs Arch Pharmacol 1980;313(2):119
voacangine  510-22-5 12-methoxyibogamine-18-carboxylic acid methyl ester  Ibogaine/*analogs & derivatives. Helv Chim Acta 59(2):532;1976
coronardine  467-77-6   Ibogaine/*analogs & derivatives. Ann Pharm Fran 33(3-4):183;1975; Planta Med 33:345;1978
voacamine  3371-85-5 12-methoxy-13-((3 alpha)-17-methoxy-17-oxovobasan- 3-yl)ibogamine-18-carboxylic acid methyl ester  Ibogaine/*analogs & derivatives.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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