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Idoxuridine

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Definition: An analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.     
Pharmacological Action Antiviral Agents; Nucleic Acid Synthesis Inhibitors 		Other names Iododeoxyuridine; 5-Iodo-2'-deoxyuridine; IUdR; OftanIDU; Oftan IDU; NSC39661; NSC 39661; Liquifilm, Herplex; Idoxuridine, 3H Labeled; Idoxuridine, 131I Labeled; Idoxuridine, 125I Labeled; Idoxuridine, 123I Labeled; 5 Iododeoxyuridine; 5 Iodo 2' deoxyuridine; 3H-Labeled Idoxuridine; 131I-Labeled Idoxuridine; 125I-Labeled Idoxuridine; 123I-Labeled Idoxuridine; Stoxil; SK&F-14287Drugs* : DENDRID; HERPLEX; STOXIL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3'-O-(3-benzenesulfonylfuroxan-4-yl)-5-iodo-2'-deoxyuridine  0   *Oxadiazoles Idoxuridine/*analogs & derivatives Iodine Radioisotopes. Nucl Med Biol 2005 Aug;32(6):641-5
5-iodo-3'-O-nitro-2'-deoxyuridine  0   Idoxuridine/*analogs & derivatives. Eur J Pharm Sci 2003 Jul;19(4):305-13
5-astato-2'-deoxyuridine  63473-09-6   Idoxuridine/*analogs & derivatives Astatine. Cancer Res 1996 Mar 15;56(6):1204-9
dioleoyl iododeoxyuridine  0   Idoxuridine/*analogs & derivatives. Biochemistry 1994 Nov 29;33(47):14073-80
idoxuridine-bleomycin protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Idoxuridine. Cancer Res 1993 Mar 15;53(6):1293-6
3'-azido-2',3'-dideoxy-5-iodouridine  85236-92-6   Idoxuridine/*analogs & derivatives Thymidine Kinase/antagonists & inhibitors. Biochem Pharmacol 1993 Jan 7;45(1):223-30
poly(dA-IdU)  59164-41-9   *Idoxuridine *Poly A-U. Nucleic Acids Res 1992 Mar 11;20(5):1109-12
3-methyl-5-(2-iodovinyl)-2'-deoxyuridine  118068-34-1   Idoxuridine/*analogs & derivatives. Drug Des Deliv 1988;3(3):223
2'-iodo-2'-deoxyuridine  4753-03-1 Uridine, 2'-deoxy-2'-iodo  *Idoxuridine Isomerism. Mol Pharmacol 1983;23(1):146
5-iodouridine  1024-99-3   Idoxuridine/*analogs & derivatives. J Virol Methods 1982;5(3-4):209
diacetylidoxuridine  0   Idoxuridine/*analogs & derivatives. Arch Ophthalmol 1981;99(9):1618
5-(2-iodovinyl)-2'-deoxyuridine  87727-68-2   Idoxuridine/*analogs & derivatives.
Pharma Action Antiviral Agents 		J Biol Chem 1981;256(12):5973
5'-deoxy-5'-iodouridine  14259-58-6 uridine, 5'-deoxy-5'-iodo  Idoxuridine/*analogs & derivatives. Int J Radiat Biol 1981;39(2):185
AIdUrd  56045-73-9 5'-amino-2',5'-dideoxy-5-iodouridine  Idoxuridine/*analogs & derivatives. Adv Ophthalmol 1979;38:90; Ann NY Acad Sci 255:332;1975; Antimicrob Agents Chemother 15(1):101;1979; Antimicrob Agents Chemother 16(1):92;1979; Biochim Biophys Acta 1980;606(2):236; J Biol Chem 251(16):4833;1976; J Biol Chem 254(20):10449;1979; J Virol 15(5):1284;1975; Proc Soc Exp Biol Med 156:92;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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