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Imipramine

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Definition: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.     
Pharmacological Action Adrenergic Uptake Inhibitors; Antidepressive Agents, Tricyclic 		Other names Imizin; Imidobenzyle; Tofranil; Pryleugan; Norchlorimipramine; Melipramine; Janimine; Imipramine Monohydrochloride; Imipramine HydrochlorideDrugs* : TOFRANIL-PM; JANIMINE; IMIPRAMINE HYDROCHLORIDE; PRESAMINE; TOFRANIL; PRAMINE; IMIPRAMINE PAMOATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
imipramine N-glucuronide  0   *Glucuronides Imipramine/*analogs & derivatives. Acta Pharmacol Sin 2006 May;27(5):623-8
10-hydroxyimipramine  796-28-1   Imipramine/*analogs & derivatives. J Chromatogr B Biomed Appl 1997 May 23;693(1):153-8
N-methylimipramine  16870-96-5   Imipramine/*analogs & derivatives. J Chromatogr 1990;528(1):143
2-iodoimipramine  124598-60-3   Imipramine/*analogs & derivatives. Mol Pharmacol 1989;36(4):620
cyan-desipramine  97744-00-8   Imipramine/*analogs & derivatives. Psychopharmacology (Berlin) 1985;86(1-2):156
2-(N,N-dimethylaminomethyl)-2,3,7,8-tetrahydro-1H-quino(1,8-ab)(1)benzazepine  78491-00-6 1H-Benzo(b)pyrido(3,2,1-jk)(1)benzazepine-2-methanamine, 2,3,7,8-tetrahydro-N,N-dimethyl-, (3R-(3alpha(2S*,5S*(2R*,6S*),6S*),4aalpha,12aalpha))  Imipramine/*analogs & derivatives. Pharm Weekbl [Sci] 1983;5(6):329
didesipramine  2095-95-6   Imipramine/*analogs & derivatives. Clin Pharmacol Ther 1983;33(3):335
2-hydroxyimipramine  303-70-8   Imipramine/*analogs & derivatives. Clin Pharmacol Ther 1982;31(3):393
2,8-dinitroimipramine  80186-88-5 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-2,8-dinitro  Imipramine/*analogs & derivatives. Life Sci 1981;28(24):2753
2-nitroimipramine  77533-92-7 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-2-nitro  Imipramine/*analogs & derivatives. Biochem Biophys Res Commun 1981;99(3):954
imipramine receptor  0   *Receptors, Drug Imipramine Receptors, Serotonin. Science 1980;210(4474):1133
ketipramine  796-29-2 5-(3-(dimethylamino)propyl)-5,11-dihydro-10H-dibenz(b,f)azepin-10-one  Imipramine/*analogs & derivatives.
cianopramine  66834-24-0 5H-Dibenz(b,f)azepine-3-carbonitrile, 5-(3-(dimethylamino)propyl)-10,11-dihydro  Imipramine/*analogs & derivatives.
Pharma Action Serotonin Antagonists 		Eur J Pharmacol 1980;61(4):409
10,11-dehydroimipramine  303-54-8 5-(3-(dimethylamino)propyl)-5H-dibenz- (b,f)azepine  Imipramine/*analogs & derivatives. Acta Psychiat Scand 55:251;1977; Clin Chem 22(6):892;1976; J Clin Pharmacol 1979;19(10):626; Med Welt 26(33-34):1457;1975; Neurol Neurocir Psiquiatr 17(4):285;1976
imipramine N-oxide  6829-98-7 10,11-dihydro- N,N-dimethyl-5H-dibenz(b,f)azepine-5-propanamine N-oxide  Imipramine/*analogs & derivatives. Acta Pharmacol Toxicol 42:58-68;1978; Acta Psychiatr Scand 49(1):77;1973; Acta Psychiatr Scand Suppl 255:47;1974

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