encyclopedia of medical concepts
ψ 
ψ 
ψ 

Immunoglobulins

More information in Books or onNLM PubMed
Definition: Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.  general: prefer specifics; /admin: consider also IMMUNOGLOBULINS, INTRAVENOUS; /defic permitted but consider also IMMUNOLOGIC DEFICIENCY SYNDROMES ; /ther use: consider also IMMUNOGLOBULIN THERAPY see IMMUNIZATION, PASSIVE; allotypes   
Pharmacological Action Immunologic Factors
See Also Immunity; Paraproteinemias
Examples Antibodies; gamma-Globulins; Immunoglobulin Constant Regions; Immunoglobulin Fragments; Immunoglobulin Subunits; Immunoglobulin Variable Region; Paraproteins; Receptors, Antigen, B-Cell 		Other names Immune Globulins; Globulins, Immune; Immunoglobulin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
immunoglobulin T, teleost  0   *Immunoglobulins Fishes. Fish Shellfish Immunol. 2011 Nov;31(5):627-34
VSIG8 protein, mouse  0   *Immunoglobulins. J Invest Dermatol. 2011 Sep;131(9):1936-8
CG3624 protein, Drosophila  0   *Membrane Proteins *Drosophila Proteins Immunoglobulins. Science. 2011 Sep 9;333(6048):1458-62
RIG-3 protein, C elegans  0   *Cell Adhesion Molecules *Caenorhabditis elegans Proteins Immunoglobulins. Neuron 2011 Jul 14;71(1):103-16
BT088 immunoglobulin, human  0   *Immunoglobulins. Transpl Int 2011 May;24(5):441-50
Nope protein, human  0   *Immunoglobulins *Nerve Tissue Proteins Carcinoma, Hepatocellular Tumor Markers, Biological. Int J Cancer. 2011 May 15;128(10):2353-63
igantibe  0   *Immunoglobulins. Dig Liver Dis 2010 Jul;42(7):509-14
GI24 protein, human  0   *Membrane Proteins Immunoglobulins. Cancer Sci 2010 Nov;101(11):2368-74
neuroplastin protein, rat  0   *Membrane Glycoproteins Immunoglobulins. FASEB J. 2010 Apr;24(4):1139-50
LY6G6D protein, human  0   *Immunoglobulins. Mol Biol (Mosk). 2009 Jul-Aug;43(4):590-8
ZIG-4 protein, C elegans  0   *Immunoglobulins *Caenorhabditis elegans Proteins. Genetics 2009 Nov;183(3):917-27
ZIG-3 protein, C elegans  0   *Immunoglobulins *Caenorhabditis elegans Proteins. Genetics 2009 Nov;183(3):917-27
Neph3 protein, mouse  0   *Immunoglobulins *Membrane Proteins. J Biol Chem 2010 Jan 1;285(1):373-80
IgSF8 protein, mouse  0   *Carrier Proteins *Membrane Proteins Immunoglobulins. Reprod Fertil Dev 2009;21(2):293-303
Skint1 protein, mouse  0   *Immunoglobulins. Nat Genet 2008 May;40(5):656-62
PUNC protein, human  0   *Immunoglobulins *Cell Adhesion Molecules, Neuronal. J Pathol 2008 Feb;214(3):357-67
Siglec-15 protein, human  0   *Immunoglobulins *Membrane Proteins. Glycobiology 2007 Aug;17(8):838-46
interferon-alpha, immunoglobulin-linked  0   *Immunoglobulins *Interferon-alpha Recombinant Fusion Proteins. Drug Chem Toxicol 2007;30(1):83-95
NPTN protein, human  0   *Membrane Glycoproteins Immunoglobulins. Neurosci Lett. 2007 Jan 16;411(3):168-73
nectin-like molecule 1, rat  0   *Cell Adhesion Molecules, Neuronal Immunoglobulins. Amino Acids 2006 Jun;30(4):409-15
lymphoglobuline  0   *Immunoglobulins. Blood 1999 Apr 1;93(7):2191-5
DIG-1 protein, C elegans  0   *Immunoglobulins *Caenorhabditis elegans Proteins. Dev Biol 2006 Nov 1;299(1):193-205
IGSF6 protein, mouse  0   *Immunoglobulins. Immunogenetics 2000 Nov;52(1-2):112-20
stretchin-klp protein, Drosophila  0   *Immunoglobulins *Drosophila Proteins Myosin-Light-Chain Kinase. J Muscle Res Cell Motil. 2005;26(4-5):213-24
Cdo protein, mouse  0   *Cell Adhesion Molecules Immunoglobulins. Dev Cell 2006 May;10(5):647-56
Vivaglobin  0   *Immunoglobulins. FDA Consum 2006 Mar-Apr;40(2):2
hepatitis C immune globulin, human  0   *Immunoglobulins. Liver Transpl 2005 Aug;11(8):941-9
Icam5 protein, mouse  0   *Membrane Glycoproteins *Nerve Tissue Proteins Immunoglobulins Cell Adhesion Molecules, Neuronal.
Madcam1 protein, rat  0   *Immunoglobulins *Mucoproteins.
MADCAM1 protein, human  0   *Immunoglobulins *Mucoproteins.
Sid4 protein, zebrafish  0   *Immunoglobulins *Zebrafish Proteins. Dev Biol 2005 Jun 1;282(1):55-69
CD40Ig protein, recombinant  0   *Recombinant Fusion Proteins Immunoglobulins Antigens, CD40. Mol Ther 2004 Oct;10(4):688-96
Igsf4c protein, mouse  0   *Immunoglobulins *Cell Adhesion Molecules.
CADM4 protein, human  0   *Immunoglobulins *Cell Adhesion Molecules.
Igsf4b protein, mouse  0   *Immunoglobulins *Cell Adhesion Molecules.
CADM3 protein, human  0   *Immunoglobulins *Cell Adhesion Molecules.
cell adhesion molecule 1, mouse  0   *Immunoglobulins *Cell Adhesion Molecules.
Izumo1 protein, mouse  0   *Immunoglobulins *Membrane Proteins. Nature 2005 Mar 10;434(7030):234-8
IZUMO1 protein, human  0   *Immunoglobulins *Membrane Proteins. Nature 2005 Mar 10;434(7030):234-8
Lilrb4 protein, mouse  0   *Membrane Glycoproteins *Receptors, Immunologic Immunoglobulins Pregnancy Proteins.
Gp49a protein, mouse  0   *Membrane Glycoproteins *Receptors, Immunologic Immunoglobulins Pregnancy Proteins.
HMCN1 protein, human  0   *Immunoglobulins Cysteine Endopeptidases. N Engl J Med 2004 Jul 22;351(4):346-53
MDGA2 protein, rat  0   *Immunoglobulins *Membrane Glycoproteins. Mol Cell Neurosci 2004 Feb;25(2):263-74
MDGA1 protein, rat  0   *Immunoglobulins GPI-Linked Proteins. Mol Cell Neurosci 2004 Feb;25(2):263-74
Igsf9 protein, mouse  0   *Immunoglobulins *Nerve Tissue Proteins.
Jam3 protein, mouse  0   *Immunoglobulins *Cell Adhesion Molecules.
Islr protein, mouse  0   *Immunoglobulins.
SYG-2 protein, C elegans  0   *Nerve Tissue Proteins *Caenorhabditis elegans Proteins Immunoglobulins Membrane Proteins. Cell 2004 Mar 19;116(6):869-81
KIRREL2 protein, human  0   *Immunoglobulins *Membrane Proteins. Genomics 2003 Aug;82(2):130-42
IGSF11 protein, human  0   *Immunoglobulins *Cell Adhesion Molecules. Int J Oncol 2003 Aug;23(2);525-31
Mxra8 protein, mouse  0   *Immunoglobulins *Membrane Proteins. Glia. 2003 Dec;44(3):190-204
DIM-1 protein, C elegans  0   *Immunoglobulins *Caenorhabditis elegans Proteins. Genetics. 2003 Mar;163(3):905-15
LY6G6F protein, human  0   *Immunoglobulins. Biochem J 2003 Oct 1;375(Pt 1):207-13
Amalgam protein, Drosophila  0   *Immunoglobulins *Drosophila Proteins. Cell 1988 Nov 18;55(4):589-600
anti-pancytokeratin immunoglobulin  0   *Immunoglobulins. Eur J Surg Oncol 2003 Apr;29(3):224-8
SYG-1 protein, C elegans  0   *Immunoglobulins *Caenorhabditis elegans Proteins Nerve Tissue Proteins. Cell 2003 Mar 7;112(5):619-30
brain- and testis-specific immunoglobulin superfamily protein, mouse  0   *Immunoglobulins Nerve Tissue Proteins. Biochem Biophys Res Commun 2002 Sep 6;296(5):1215-21
SynCAM protein, rat  0   *Immunoglobulins *Cell Adhesion Molecules. Science 2002 Aug 30;297(5586):1525-31
BIVM protein, Giardia lamblia  0   *Immunoglobulins *Protozoan Proteins. Genomics 2002 Jun;79(6):750-5
IGSF9 protein, human  0   *Immunoglobulins *Nerve Tissue Proteins. Genomics 2002 May;79(5):663-70
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy