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Immunoglobulin Heavy Chains

More information in Books or onNLM PubMed
Definition: The largest of polypeptide chains comprising immunoglobulins. They contain 450 to 600 amino acid residues per chain, and have molecular weights of 51-72 kDa.  gammopathy: coordinate IMMUNOGLOBULIN HEAVY CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text; DF: IG HEAVY CHAIN   
Pharmacological Action Immunologic Factors
See Also Heavy Chain Disease
Examples Immunoglobulin alpha-Chains; Immunoglobulin delta-Chains; Immunoglobulin epsilon-Chains; Immunoglobulin gamma-Chains; Immunoglobulin mu-Chains 		Other names Immunoglobulins, Heavy-Chain; Immunoglobulins, Heavy Chain; Immunoglobulin Heavy Chain Subgroup VH III; Immunoglobulin Heavy Chain Subgroup VH I; Heavy Chains, Immunoglobulin; Heavy Chains, Ig; Heavy Chain, Immunoglobulin; Heavy Chain Immunoglobulins; Immunoglobulin Heavy Chain Subgroup VH-III; Immunoglobulin Heavy Chain Subgroup VH-I; Immunoglobulin Heavy Chain; Ig Heavy Chains; Heavy-Chain Immunoglobulins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ALZ 0081  0   *Immunoglobulin Heavy Chains. Blood 2011 Jul 21;118(3):757-65
HS1,2-A enhancer protein, human  0   *Immunoglobulin Heavy Chains. J Invest Dermatol. 2008 Aug;128(8):1920-4
immunoglobulin zeta, zebrafish  0   *Immunoglobulin Heavy Chains *Zebrafish Proteins Immunoglobulin Isotypes. Food Chem Toxicol 2005 Apr;43(4):617-22
ARID3A protein, human  0   *DNA-Binding Proteins *Transcription Factors Immunoglobulin Heavy Chains.
heavy chain, monoclonal antibody B23  0   *Antibodies, Monoclonal *Immunoglobulin Heavy Chains. Gene 1996 Mar 9;169(2):237-9
immunocorticotropin  150035-99-7 L-Valine, N-(N2-(N-(N-(N-(N-(1-(N2-(N2-L-valyl-L-lysyl)-L-lysyl)-L-prolyl)glycyl)-L-seryl)-L-seryl)-L-valyl)-L-lysyl)  *Immunoglobulin G *Peptide Fragments Adrenocorticotropic Hormone Immunoglobulin Variable Region Immunoglobulin Heavy Chains. Int J Pept Protein Res 1993 Jun;41(6):517-21
molecular chaperone GRP78  0   *Heat-Shock Proteins Adenosine Triphosphatases Autoantigens Immunoglobulin Heavy Chains. J Cell Biol 1986;102(5):1558
prolactin-binding protein  0   *Carrier Proteins Immunoglobulin Heavy Chains Immunoglobulin Light Chains Prolactin. Endocrinol Exp (Bratisl) 1981;15(1):55

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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