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Indoleacetic Acids

More information in Books or onNLM PubMed
Definition: Acetic acid derivatives of the heterocyclic compound indole. (Merck Index, 11th ed)     
Pharmacological Action Plant Growth Regulators
Examples Etodolac; Hydroxyindoleacetic Acid
Other names Acids, Indolylacetic; Acids, Indoleacetic; Indolylacetic Acids; Auxins; Auxin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(5-fluoro-2-methyl-3-quinolin-2-ylmethylindo-1-yl)acetic acid  0   *Indoleacetic Acids *Quinolines. J Pharmacol Exp Ther. 2012 Feb;340(2):473-82.
(2-(1-(3-methoxycarbonylmethyl-1H-indol-2-yl)-1-methylethyl)-1H-indol-3-yl)acetic acid methyl ester  0   *Indoleacetic Acids Intercalating Agents. Mol Biosyst 2011 Mar 1;7(3):766-72
1-(4-chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acid morpholineamide  0   *Indoleacetic Acids *Morpholines Receptor, Cannabinoid, CB2/agonists. Prostaglandins Other Lipid Mediat 2011 Feb;94(1-2):17-24
argiotoxin-636  0   *Indoleacetic Acids *Polyamines Spider Venoms. J Nat Prod. 2011 Mar 25;74(3):483-6
RO 5066852  0   *Indoleacetic Acids *Naphthalenes Chymases/antagonists & inhibitors. Cardiovasc Res 2011 Jan 1;89(1):244-52
(5-(3-(4-(biphenyl-4-ylcarbonyl)phenoxy)propoxy)-1H-indol-1-yl)acetic acid  0   *Benzophenones *Indoleacetic Acids PPAR gamma/agonists. ChemMedChem 2010 Oct 4;5(10):1707-16
2-methyl-indole-3-acetic acid  0   *Indoleacetic Acids. J Biochem Mol Toxicol. 2010 May;24(3):165-73
(3-aminooxalyl-1-benzyl-2-ethyl-6-methyl-1H-indol- 4-yloxy)-acetic acid methyl ester  0   *Indoleacetic Acids Phospholipases A2, Secretory/antagonists & inhibitors. Exp Lung Res 2010 May;36(4):191-200
indoleacetic acid falcarindiol ester  0   *Diynes *Fatty Alcohols *Indoleacetic Acids. Planta Med 2009 Jan;75(1):49-54
4-trifluoromethylindole-3-acetic acid  0   *Indoleacetic Acids. Biosci Biotechnol Biochem 2008 Aug;72(8):2025-33
1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-3-indoleacetic acid  0   *Indoleacetic Acids. Phamacol Res 2007 Oct;56(4):335-43
N-beta-D-glucopyranosyl indole-3-acetic acid  0   *Indoleacetic Acids *Monosaccharides. Phytochemistry. 2007 Oct;68(20):2512-22
5-(1-(1-carboxy-2-mercaptoethylcarbamoyl)-2-(4-hydroxyphenyl)ethylamino)-4-(2-1H-indol-3-ylacetylamino)pentanoic acid  0   *Indoleacetic Acids *Oligopeptides Ligands. J Med Chem 2007 Sep 6;50(18):4329-39
N-(6-hydroxyindol-3-ylacetyl)-valine  0   *Indoleacetic Acids Valine/*analogs & derivatives. Phytochemistry 2007 Jun;68(12):1651-63
1-O-(2-oxoindol-3-ylacetyl)-beta-D-glucopyranose  0   *Glucosides *Indoleacetic Acids. Phytochemistry 2007 Jun;68(12):1651-63
N-(6-hydroxyindol-3-ylacetyl)-phenylalanine  0   *Indoleacetic Acids Phenylalanine/*analogs & derivatives. Phytochemistry 2007 Jun;68(12):1651-63
methyl-3-indolylacetate  0   *Indoleacetic Acids. Mol Cancer Ther 2006 Dec;5(12):3285-93
pactimibe  0   *Indoleacetic Acids Sterol O-Acyltransferase/antagonists & inhibitors. N Engl J Med 2006 Mar 23;354(12):1253-63
2-(5-(3-(6-benzoyl-1-propylnaphthalene-2-yloxy)propoxy)indol-1-yl)ethanoic acid  0   *Indoleacetic Acids *Naphthalenes Peroxisome Proliferator-Activated Receptors/agonists. J Med Chem 2006 Feb 9;49(3):1212-6
lidorestat  0   *Indoleacetic Acids *Thiazoles Aldehyde Reductase/antagonists & inhibitors. J Med Chem 2005 May 5;48(9):3141-52
tiplaxtinin  0   *Indoleacetic Acids Plasminogen Activator Inhibitor 1. Arterioscler Thromb Vasc Biol 2005 Feb;25(2):365-71; J Med Chem 2004 Jul 1;47(14):3491-4
DFL2 protein, Arabidopsis  0   *Arabidopsis Proteins Indoleacetic Acids Plant Growth Regulators. Plant Cell Physiol 2003 Oct;44(10):1071-80
(6-chloro-2-(4-chlorobenzoyl)-1H-indol-3-yl)acetic acid  0   *Chlorobenzoates *Indoleacetic Acids. J Org Chem 2003 May 16;68(10):4104-7
methyl-1-benzyl-5-methoxy-1H-indole-3-acetate  0   *Indoleacetic Acids. J Org Chem 2002 Apr 5;67(7):2252-6
5-Fluoroindole-3-acetic acid  0   *Indoleacetic Acids Prodrugs. Biochem Pharmacol 2002 Jan 15;63(2):265-72
2-(5,6-dichloro-3-indolyl)propionic acid  0   *Indoles *Propionic Acids Indoleacetic Acids. Biosci Biotechnol Biochem 2001 Feb;65(2):270-6
DFL1 protein, Arabidopsis  0   *Arabidopsis Proteins Indoleacetic Acids. Plant J 2001 Jan;25(2):213-21
N-(pyridin-4-yl)-(1-(4-fluorobenzyl)indol-3-yl)acetamide  0   *Indoleacetic Acids *Pyridines Polyunsaturated Alkamides. J Med Chem 1999 Feb 25;42(4):638-48
secaloside C  0   *Glucosides *Indoleacetic Acids Stereoisomerism. J Nat Prod 1997 Apr;60(4):356-60
secaloside A  0   *Glucosides *Indoleacetic Acids Stereoisomerism. J Nat Prod 1997 Apr;60(4):356-60
ParAt protein, Nicotiana tabacum  0   *Plant Proteins Indoleacetic Acids. DNA Res 1994;1(5):213-21
ParAs protein, Nicotiana tabacum  0   *Plant Proteins Indoleacetic Acids. DNA Res 1994;1(5):213-21
5-chloroindole-3-acetic acid  1912-45-4   *Indoleacetic Acids. J Bacteriol 1995 Oct;177(20):5762-6
4-chloroindole-3-acetic acid  2519-61-1   *Indoleacetic Acids. J Bacteriol 1995 Oct;177(20):5762-6
S-(2-(1-carboxy-2-methylpropyl)isoindole-1-yl)-N-acetylcysteine  126478-70-4   *Indoleacetic Acids *Isoindoles Acetylcysteine/*analogs & derivatives. Electrophoresis 1994 Jun;15(6):763-8
2-hexylindole-3-acetamide-N-benzenetricarboxylic acid  152842-64-3 1,2-Benzenedicarboxylic acid, 4-((3-(2-(dihexylamino)-2-oxoethyl)-2-(4-fluorophenyl)-1H-indol-1-yl)carbonyl)  *Indoleacetic Acids *Tricarboxylic Acids. J Pharmacol Exp Ther 1993 Oct;267(1):462-71
auxin-binding protein 1  0   *Plant Proteins *Receptors, Cell Surface Indoleacetic Acids. Plant Mol Biol 1993 Oct;23(1):57-66
endoplasmic reticulum auxin-binding protein 4, Zea mays  0   *Receptors, Cell Surface Indoleacetic Acids Plant Proteins. Plant Mol Biol 1993 Oct;23(1):57-66
N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide  142720-24-9 1H-Indole-3-acetamide, 2-(4-fluorophenyl)-N,N-dihexyl  *Indoleacetic Acids. J Pharmacol Exp Ther 1993 May;265(2):649-56
iaaM protein, Agrobacterium  0   *Bacterial Proteins Indoleacetic Acids. J Bacteriol 1993 May;175(10):3151-60
SR 27897  136381-85-6 1H-Indole-1-acetic acid, 2-(((4-(2-chlorophenyl)-2-thiazolyl)amino)carbonyl)  *Indoleacetic Acids *Thiazoles.
Pharma Action Hormone Antagonists
Eur J Pharmacol 1993 Feb 23;232(1):13-9
SC 50132  132623-16-6   *Indoleacetic Acids. Neuropharmacology 1993 Feb;32(2):139-47
SC 49648  132004-39-8   *Indoleacetic Acids. Neuropharmacology 1993 Feb;32(2):139-47
MK 410  40738-05-4   *Indoleacetic Acids. Arch Biochem Biophys 1993 Jan;300(1):132-6
indole-3-acetic acid ethyl ester  778-82-5   *Indoleacetic Acids. Mol Gen Genet 1991;228(3):361
5-azido-1H-indole-3-acetic acid  79473-10-2   *Azides *Indoleacetic Acids. J Biol Chem 1991;266(12):7393
4,6-diethyl-1,3,4,5-tetrahydropyrano(4,3-b)indole-4-acetic acid  122761-89-1   *Indoleacetic Acids. J Med Chem 1989;32(9):2135
1-isobutyl-2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-3-indoleacetic acid  121625-72-7   *Indoleacetic Acids. Arzneimittelforschung 1989;39(5):548
C 8778-GO  121625-71-6   *Indoleacetic Acids. Arzneimittelforschung 1989;39(5):548
pemedolac  103024-44-8   *Indoleacetic Acids. J Med Chem 1988;31(6):1244
4-ureidoetodolac  111478-85-4 Pyrano(3,4-b)indole-1-acetic acid, 4-((aminocarbonyl)amino)-1,8-diethyl-1,3,4,9-tetrahydro  *Indoleacetic Acids. Drug Metab Dispos 1987;15(6):921
desproglumideproglumetacin  97460-20-3   *Indoleacetic Acids. Eur J Pharmacol 1987;142(2):245
apyramide  68483-33-0   *Indoleacetic Acids. Drugs Exp Clin Res 1987;13(5):247
2-(indol-3-ylmethyl)indol-3-ylacetic acid  68232-56-4   *Indoleacetic Acids. J Bacteriol 1987;169(12):5859
argiotoxin 673  111924-44-8 Butanediamide, N1-(15,20-diamino-20-imino-4,9-dimethyl-14-oxo-4,9,13,19-tetraazaeicos-1-yl)-2-(((2,4-dihydroxyphenyl)acetyl)amino)-, (S-(R*,R*))  *Indoleacetic Acids *Polyamines Spider Venoms. Biochem Biophys Res Commun 1987;148(2):678
argiotoxin 659  111944-83-3 Butanediamide, N1-(16,21-diamino-21-imino-15-oxo-6,10,14,20-tetraazaheneicos-1-yl)-2-(((4-hydroxy-1H-indol-3-yl)acetyl)amino)-, (S-(R*,R*))  *Indoleacetic Acids *Polyamines Spider Venoms. Biochem Biophys Res Commun 1987;148(2):678
indole-3-acetyl-epsilon-lysine  17929-68-9   *Indoleacetic Acids Lysine/*analogs & derivatives. J Bacteriol 1986;166(2):598
auxin receptor, plant  0   *Plant Proteins *Receptors, Cell Surface Indoleacetic Acids. J Biol Chem 1985;260(17):9848
indol-3-ylacetylinositol galactoside  0   *Indoleacetic Acids. J Biochem 1982;207(2):283
1-O-indol-3-ylacetylglucose  19817-95-9   *Indoleacetic Acids. Biochem J 1982;207(2):273
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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