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Insulin, Isophane

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Definition: An intermediate-acting INSULIN preparation with onset time of 2 hours and duration of 24 hours. It is produced by crystallizing ZINC-insulin-PROTAMINES at neutral pH 7. Thus it is called neutral protamine Hagedorn for inventor Hans Christian Hagedorn.     
Pharmacological Action Hypoglycemic Agents 		Other names Insulin, NPH; Zinc Insulin, Protamine; Regular Isophane Insulin; Protamine Zinc Insulin; Isophane Insulin; Hagedorn Insulin, Protamine; Protamine Hagedorn Insulin; Neutral Protamine Hagedorn Insulin; NPH Insulin; Isophane Insulin, Regular; Insulin, Protamine ZincDrugs* : NPH INSULIN; HUMULIN 70/30 PEN; HUMULIN 70/30; NOVOLIN 70/30; MIXTARD HUMAN 70/30; NPH PURIFIED PORK ISOPHANE INSULIN; NOVOLIN N; NPH ILETIN I (BEEF-PORK); INSULIN INSULATARD NPH NORDISK; NPH ILETIN II; HUMULIN 50/50; NPH ILETIN II (PORK); HUMULIN N; INSULATARD NPH HUMAN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
insulin, protamine zinc, beef-pork  0   *Insulin, Isophane *Insulin, Regular, Pork.
Pharma Action Hypoglycemic Agents
isophane insulin, pork  0   *Insulin, Isophane *Insulin, Regular, Pork.
Pharma Action Hypoglycemic Agents
isophane insulin, human  0   *Insulin, Isophane *Insulin, Regular, Human. NOVOLIN L; HUMULIN L
isophane insulin, beef-pork  0   *Insulin, Isophane *Insulin, Regular, Pork.
Pharma Action Hypoglycemic Agents
isophane insulin, beef  0   *Insulin, Isophane.
Pharma Action Hypoglycemic Agents
insulin, pork; isophane insulin, pork drug combination 30:70  0   *Insulin, Isophane *Biphasic Insulins *Insulin, Regular, Pork.
Pharma Action Hypoglycemic Agents
insulin aspart, insulin aspart protamine drug combination 30:70  0   *Insulin, Isophane *Biphasic Insulins *Insulin Aspart.
Pharma Action Hypoglycemic Agents 		NOVOLOG MIX 50/50; NOVOLOG MIX 70/30
isophane insulin, insulin lispro drug combination 50:50  0   *Insulin, Isophane *Biphasic Insulins *Insulin Lispro.
Pharma Action Hypoglycemic Agents
insulin lispro, isophane insulin lispro drug combination (25:75)  0   *Insulin, Isophane *Biphasic Insulins *Insulin Lispro. Acta Diabetol 2003 Dec;40(4):187-92

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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