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Interferon-gamma

More information in Books or onNLM PubMed
Definition: The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.     
Pharmacological Action Antiviral Agents
See Also Interferon-gamma Release Tests 		Other names gamma-Interferon; Interferon, Immune; Interferon Type II; Interferon, Type II; Immune Interferon; Type II Interferon; Interferon, gamma
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
interferon gamma-1b  0   *Interferon-gamma Recombinant Proteins.
IFN-gamma(95-132) peptide  0   *Interferon-gamma *Peptide Fragments. J Immunol 2007 Apr 1;178(7):4576-83
MC2 peptide  0   *Interferon-gamma *Peptide Fragments. Int Immunopharmacol 2005 Oct;5(11):1622-32
TJU 103  0   *Organic Chemicals Interferon-gamma/antagonists & inhibitors Interleukin-1/antagonists & inhibitors Tumor Necrosis Factor-alpha/antagonists & inhibitors Interleukin-6/antagonists & inhibitors. Antimicrob Agents Chemother 2000 Apr;44(4):1067-9
interferon receptor, type II  0   *Receptors, Interferon Interferon-gamma. Immunol Cell Biol 1999 Apr;77(2):153-63
T lymphocyte triggering factor, Trypanosoma brucei  0   *Protozoan Proteins Interferon-gamma T-Lymphocytes. J Exp Med 1997 Aug 4;186(3):433-8
interferon-gamma (95-133)  0   *Interferon-gamma *Peptide Fragments. J Interferon Cytokine Res 1996 Oct;16(10):813-7
Fv-interferon gamma  0   *Immunoglobulin Fragments *Interferon-gamma Recombinant Fusion Proteins. Cancer Biother 1993 Winter;8(4):327-37
interferon gamma receptor  0   *Receptors, Interferon Interferon-gamma. Proc Natl Acad Sci U S A 1992 Dec 1;89(23):11317-21
interferon gamma (1-39)  0   *Interferon-gamma *Peptide Fragments. Biochemistry 1991;30(23):5784
interferon gamma-4A  0   *Interferon-gamma Recombinant Proteins. J Biol Response Mod 1988;7(3):309
interferon gamma, Cys(-3), Tyr(-2), Cys(-1)  98513-32-7   *Interferon-gamma Recombinant Proteins. J Interferon Res 1986;6(6):639
glycosylated gamma interferon  0   *Interferon-gamma Glycosylation. J Interferon Res 1985;5(3):471

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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