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Iodine Radioisotopes

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Definition: Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.  I-117 through I-139 except I-127; NIM; /blood-csf-urine /metab permitted but not for tracer studies (   
Examples Serum Albumin, Radio-Iodinated 		Other names Radioisotopes, IodineDrugs* : SODIUM IODIDE I 123; HICON; SODIUM IODIDE I 131; JEANATOPE; SODIUM IODIDE I-131; IODOTOPE; RADIOIODINATED SERUM ALBUMIN (HUMAN) IHSA I 125; RADIO-IODINATED (I 125) SERUM ALBUMIN (HUMAN)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(N-tert-butylamino)-3'-iodo-4'-azidopropiophenone  0   *Azides Bupropion/*analogs & derivatives Iodine Radioisotopes. Biochemistry. 2012 Mar 27;51(12):2425-35.
3-(iodobenzoyl)norbiotinamide-PTD-ODD-SAV fusion protein  0   *Recombinant Fusion Proteins Biotin/*analogs & derivatives Iodine Radioisotopes. Cancer Sci. 2011 Nov;102(11):2090-6.
IBMF3 peptide  0   *Iodobenzenes *Peptides Iodine Radioisotopes. PLoS One 2011;6(7):e22418
2-((2-iodophenoxy)phenylmethyl)morpholine  0   *Iodobenzenes *Morpholines Iodine Radioisotopes. Synapse 2011 Jul;65(7):658-67
Yamada peptide 20  0   *Oligopeptides Iodine Radioisotopes. Eur J Pharmacol 2010 Dec 15;649(1-3):59-63
N-(2-(4-(4-iodobenzyl)piperidin-1-ylmethyl)benzoimidazol-5-yl)-methanesulfonamide  0   *Benzimidazoles *Sulfonamides Iodine Radioisotopes. Bioorg Med Chem 2010 Nov 1;18(21):7497-506
2-((4-(4-iodobenzyl)piperidin-1-yl)methyl)benzimidazol-5-ol  0   *Benzimidazoles Iodine Radioisotopes. Bioorg Med Chem 2010 Nov 1;18(21):7497-506
4-iodophenyl 1,4-diazaicyclo(3.2.2)nonane-4-carboxylate  0   *Azabicyclo Compounds Iodine Radioisotopes. Brain Res 2010 Nov 11;1360:130-7
5-(formyl-(3-(formyl-(3,5-bis (2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodophenyl) amino)-2-hydroxypropyl)amino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide  0   *Formamides *Triiodobenzoic Acids Iodine Radioisotopes. Acta Radiol 2010 Nov;51(9):1014-20
4-hydroxy-4-(4-(2-azido-5-iodobenzyloxy)phenyl)butanoic acid  0   *Azides *Phenylbutyrates Iodine Radioisotopes. J Pharmacol Exp Ther 2010 Nov;335(2):458-64
4-hydroxy-4-(4-(2-iodobenzyloxy)phenyl)butanoic acid  0   *Phenylbutyrates Iodine Radioisotopes. J Pharmacol Exp Ther 2010 Nov;335(2):458-64
N-(2-diethylaminoethyl)-4-(4-fluorobenzamido)-5-iodo-2-methoxybenzamide  0   *Benzamides Iodine Radioisotopes. Cancer Res 2010 May 15;70(10):4045-53
4'-(2-chloro-6-(3-iodobenzylamino)purine)-2',3'-O-dihydroxy-bicyclo(3.1.0)hexane  0   Adenosine/*analogs & derivatives Iodine Radioisotopes Receptor, Adenosine A3/agonists. Biochem Pharmacol 2010 Apr 1;79(7):967-73
2-(4-iodophenylamino)pyrido(2,3-d)pyrimidin-7-one  0   *Pyridones *Pyrimidines Iodine Radioisotopes. Nucl Med Biol 2005 May;32(4):313-21
1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxylate  0   *Piperidines *Pyrazoles Iodine Radioisotopes. Bioorg Med Chem Lett 2009 Nov 1;19(21):6209-12
20-iodo-14,15-epoxyeicosa-5-enoic acid  0   *Epoxy Compounds 8,11,14-Eicosatrienoic Acid/*analogs & derivatives Iodine Radioisotopes. J Pharmacol Exp Ther 2009 Dec;331(3):1137-45
N,N-diethyl-2-(2-(3-iodo-4-methoxyphenyl)-5,7-dimethylpyrazolo(1,5-a)pyrimidin-3-yl)acetamide  0   *Acetamides *Pyrimidines Iodine Radioisotopes. Biochem Biophys Res Commun 2009 Nov 6;389(1):80-3
5-iodo-N-(2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl)-2-methoxybenzamide  0   *Benzamides *Isoquinolines Iodine Radioisotopes. Appl Radiat Isot 2009 Apr;67(4):594-7
methyl-3-(1'-iodobenzyloxyethyl)pyropheophorbide-a  0   Chlorophyll/*analogs & derivatives Iodine Radioisotopes. J Med Chem 2009 Jan 22;52(2):445-55
N-(2-diethylaminoethyl)-6-iodoquinoxaline-2-carboxamide  0   *Quinoxalines Iodine Radioisotopes. J Med Chem 2008 Jun 12;51(11):3133-44
iodophenyl metomidate  0   Etomidate/*analogs & derivatives Iodine Radioisotopes. J Med Chem 2008 Apr 10;51(7):2244-53
N(4)-(2-(diethylamino)ethyl)-2-iodo-N(1)-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide  0   *Oligopeptides *Phthalic Acids Iodine Radioisotopes. J Med Chem 2008 Feb 28;51(4):1043-7
2-carbomethoxy-3-(3'-iodophenyl)tropane  0   Cocaine/*analogs & derivatives Iodine Radioisotopes. Nucl Med Biol 2008 Jan;35(1):53-9
N-methyl-3-(3-iodopyridin-2-yloxy)-3-phenylpropylamine  0   *Propylamines *Pyridines Iodine Radioisotopes. Nucl Med Biol 2008 Jan;35(1):43-52
2-amino-2-methyl-4-iodo-3-butenoic acid  0   Alanine/*analogs & derivatives Iodine Radioisotopes. J Med Chem 2007 Dec 27;50(26):6718-21
2-hydroxy-5-(3-iodoprop-2-en-1-oxy)-3-(4-phenylpiperidino)tetralin  0   *Piperidines *Tetrahydronaphthalenes Iodine Radioisotopes Ligands. Nucl Med Biol 2007 Nov;34(8):967-71
1-(4-(hydroxymethyl)-2-cyclopenten-1-yl)-5-iodouracil  0   Uridine/*analogs & derivatives Iodine Radioisotopes. J Med Chem 2007 Nov 29;50(24):6032-8
2-carbo(2-fluoroethoxy)-3-(4'-(2-iodoethenyl)phenyl)nortropane  0   *Nortropanes Fluorine Radioisotopes Iodine Radioisotopes. J Med Chem 2007 Sep 20;50(19):4553-60
N-(1-(2-fluoroethyl)piperidin-4-yl)-4-iodobenzamide  0   *Benzamides *Piperidines Iodine Radioisotopes. J Med Chem 2007 Jul 26;50(15):3561-72
4-acetamido-N-(4-(N-butyl-N-methylamino)butyl)-5-iodo-2-methoxybenzamide  0   *Acetanilides *Benzamides Iodine Radioisotopes. J Med Chem 2007 Jul 26;50(15):3561-72
2-((4-dimethylaminophenyl)methylene)-5-iodo-3(2H)-benzofuranone  0   *Benzofurans *Benzylidene Compounds Iodine Radioisotopes. Biochem Biophys Res Commun 2007 Sep 14;361(1):116-21
5-iodo-2-((4-methylaminophenyl)methylene)-3(2H)-benzofuranone  0   *Benzofurans *Benzylidene Compounds Iodine Radioisotopes. Biochem Biophys Res Commun 2007 Sep 14;361(1):116-21
2-((4-aminophenyl)methylene)-5-iodo-3(2H)-benzofuranone  0   *Benzofurans *Benzylidene Compounds Iodine Radioisotopes. Biochem Biophys Res Commun 2007 Sep 14;361(1):116-21
monoiodohypericin monocarboxylic acid  0   Perylene/*analogs & derivatives Iodine Radioisotopes. Bioorg Med Chem Lett 2007 Jul 15;17(14):
2-(2'-phosphoryloxyphenyl)-6-iodo-4-(3H)-quinazolinone  0   *Phosphoric Acid Esters *Quinazolinones Iodine Radioisotopes. Bioconjug Chem 2007 May-Jun;18(3):754-64
3'-fluoro-5-iodo-2'-deoxyuridine  0   Deoxyuridine/*analogs & derivatives Iodine Radioisotopes. Nucl Med Biol 2007 Apr;34(3):273-81
ioflupane  0   *Nortropanes Iodine Radioisotopes. Eur J Neurol 2007 Mar;14(3):297-9
7'-iodorotenol  0   Rotenone/*analogs & derivatives Iodine Radioisotopes. Nucl Med Biol 2007 Jan;34(1):109-16
N-(5-fluoro-2-phenoxyphenyl)-N-(2-iodo-5-methoxybenzyl)acetamide  0   *Acetamides *Aniline Compounds Iodine Radioisotopes Ligands. J Med Chem 2007 Feb 22;50(4):848-55
2-(6-iodo-3-pyridinyl)-7-azabicyclo(2.2.1)heptane  0   *Pyridines *Bicyclo Compounds, Heterocyclic Iodine Radioisotopes. J Nucl Med 2005 Jan;46(1):130-40
2-(alpha-(2-iodophenoxy)benzyl)morpholine  0   *Morpholines Iodine Radioisotopes. Eur J Nucl Med Mol Imaging 2006 Jun;33(6):639-47
3'-(5-iodothiophen-2-yl)spiro(1-azabicyclo(2.2.2)octane-3,5'-(1',3')oxazolidin)-2'-one  0   *Oxazoles *Quinuclidines Iodine Radioisotopes. Nucl Med Biol 2006 Apr;33(3):311-6
SIP(L19) fusion protein  0   *Antibodies *Recombinant Fusion Proteins Iodine Radioisotopes. Nucl Med Biol 2006 Jul;33(5):661-6
N',N'-dimethyl-6-methyl-(4'-iodophenyl)imidazo(1,2-a)pyridine-3-acetamide  0   *Imidazoles *Pyridines Iodine Radioisotopes Ligands. Life Sci 2006 Jun 13;79(3):287-94
2-(4'-iodobiphenyl-4-sulfonylamino)-3-methylbutyramide  0   *Butyric Acids *Sulfonamides Iodine Radioisotopes. Appl Radiat Isot 2006 Jun;64(6):677-85
2-(4'-iodobiphenyl-4-sulfonylamino)-3-methylbutyric acid  0   *Butyric Acids *Sulfonamides Iodine Radioisotopes. Appl Radiat Isot 2006 Jun;64(6):677-85
5-(4-iodophenyl)-1-(4-(aminosulfonyl)phenyl)-3-trifluoromethyl-1H-pyrazole  0   *Pyrazoles *Sulfonamides Iodine Radioisotopes. Nucl Med Biol 2006 Jan;33(1):21-7
5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-trifluoromethyl-1H-pyrazole  0   *Pyrazoles *Sulfones Iodine Radioisotopes. Nucl Med Biol 2006 Jan;33(1):21-7
angiotensin II, iodo-Sar(1)-Tdf(8)  0   Angiotensin II/*analogs & derivatives Iodine Radioisotopes. J Med Chem 2006 Apr 6;49(7):2200-9
18-(4-iodophenyl)octadecylphosphocholine  0   Phosphorylcholine/*analogs & derivatives Iodine Radioisotopes. J Med Chem 2006 Apr 6;49(7):2155-65
O(6)-(5-iodobenzyl)guanine  0   Guanine/*analogs & derivatives Iodine Radioisotopes O(6)-Methylguanine-DNA Methyltransferase/antagonists & inhibitors. J Med Chem 2006 Jan 12;49(1):263-72
O(6)-(5-iodothenyl)guanine  0   Guanine/*analogs & derivatives Iodine Radioisotopes O(6)-Methylguanine-DNA Methyltransferase/antagonists & inhibitors. J Med Chem 2006 Jan 12;49(1):263-72
131I-rituximab  0   *Antibodies, Monoclonal, Murine-Derived Iodine Radioisotopes. Eur J Nucl Med Mol Imaging 2005 Oct;32(10):1225-33
3'-O-(3-benzenesulfonylfuroxan-4-yl)-5-iodo-2'-deoxyuridine  0   *Oxadiazoles Idoxuridine/*analogs & derivatives Iodine Radioisotopes. Nucl Med Biol 2005 Aug;32(6):641-5
N-(N-((S)-1,3-dicarboxypropyl)carbamoyl)-S-3-iodo-L-tyrosine  0   Carbamates Tyrosine/*analogs & derivatives Iodine Radioisotopes. Neurosci Lett. 2005 Oct 28;387(3):141-4
N-(3-(acridin-9-yl)propyl)-3-iodobenzamide  0   *Acridines *Benzamides Iodine Radioisotopes. Int J Oncol 2005 Nov;27(5):1355-60
2-iodophenyl-(1-(1-methylpiperidin-2-ylmethyl)-1H-indol-3-yl)methanone  0   *Indoles *Piperidines Iodine Radioisotopes. J Med Chem 2005 Oct 6;48(20):6386-92
methyl 3-(1'-3-iodobenzyloxyethyl)-3-devinylpyropheophorbide-a  0   Chlorophyll/*analogs & derivatives Iodine Radioisotopes. J Med Chem 2005 Oct 6;48(20):6286-95
6-chloro-2-(4'-iodophenyl)-3-(N,N-diethyl)imidazo(1,2-a)pyridine-3-acetamide  0   *Bicyclo Compounds, Heterocyclic Iodine Radioisotopes. Eur J Nucl Med Mol Imaging 2005 May;32(5):557-63
5-iodo-R 91150  0   *Piperidines Iodine Radioisotopes Ligands. Eur J Nucl Med Mol Imaging 2005 Jun;32(6):708-16
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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