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Iron-Sulfur Proteins

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Definition: A group of proteins possessing only the iron-sulfur complex as the prosthetic group. These proteins participate in all major pathways of electron transport: photosynthesis, respiration, hydroxylation and bacterial hydrogen and nitrogen fixation.  /biosyn /physiol permitted   
Examples Adrenodoxin; Ferredoxin-Nitrite Reductase; Ferredoxins; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Ferrochelatase; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Nitrate Reductase (NAD(P)H); Nitrate Reductase (NADPH) 		Other names Sulfur Proteins, Iron; Proteins, Iron-Sulfur; Proteins, Iron Sulfur; Iron Sulfur Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TYW1 protein, S cerevisiae  EC 1.-   *Oxidoreductases *Saccharomyces cerevisiae Proteins Iron-Sulfur Proteins. J Biol Chem. 2011 Nov 4;286(44):38488-97.
Isa2 protein, S pombe  0   *Iron-Sulfur Proteins *Schizosaccharomyces pombe Proteins. Biochem Biophys Res Commun 2010 Feb 12;392(3):467-72
Isa1 protein, S pombe  0   *Iron-Sulfur Proteins *Schizosaccharomyces pombe Proteins. Biochem Biophys Res Commun 2010 Feb 12;392(3):467-72
SDH2 protein, S cerevisiae  0   *Succinate Dehydrogenase *Saccharomyces cerevisiae Proteins Iron-Sulfur Proteins Protein Subunits. Hum Mol Genet 2009 May 15;18(10):1860-8
NrfC protein, E coli  0   *Iron-Sulfur Proteins *Escherichia coli Proteins. EMBO J 2008 Aug 6;27(15):2055-63
YeaW protein, E coli  0   *Iron-Sulfur Proteins *Escherichia coli Proteins. Biometals 2008 Aug;21(4):459-67
HcaC protein, E coli  0   *Iron-Sulfur Proteins *Escherichia coli Proteins. Biometals 2008 Aug;21(4):459-67
Dre2 protein, S cerevisiae  0   *Iron-Sulfur Proteins *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2008 Sep;28(18):5569-82
NfuA protein, E coli  0   *Iron-Sulfur Proteins *Escherichia coli Proteins. J Biol Chem 2008 May 16;283(20):14084-91
THIC protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins. Proc Natl Acad Sci U S A 2007 Dec 4;104(49):19637-42
IscU protein, mouse  0   *Iron-Sulfur Proteins. Arch Biochem Biophys 2007 Sep 1;465(1):282-92
ErpA protein, E coli  0   *Iron-Sulfur Proteins *Escherichia coli Proteins. Proc Natl Acad Sci U S A 2007 Aug 21;104(34):13626-31
CnfU-V protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins. Plant Cell 2004 Apr;16(4):993-1007
IscA-I protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins. Biochem Biophys Res Commun 2006 Feb 24;340(4):1047-52
NarG protein, E coli  EC 1.7.99.4   *Escherichia coli Proteins *Nitrate Reductase Iron-Sulfur Proteins Protein Subunits. J Biol Chem 2006 Jan 27;281(4):2170-6
ISCU protein, human  0   *Iron-Sulfur Proteins. J Cell Sci. 2005 Sep 1;118(Pt 17):3917-24
Nar1 protein, S cerevisiae  EC 1.18.99.1   *Hydrogenase *Iron-Sulfur Proteins *Saccharomyces cerevisiae Proteins. EMBO J 2004 May 19;23(10):2105-15
(CH3)3NCH2CONH2)2(Fe4S4((tBuS)4)  0   *Iron-Sulfur Proteins. Inorg Chem 2005 May 30;44(11):3777-9
SDH2-3 protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins Succinate Dehydrogenase Protein Subunits. Plant Mol Biol 2001 May;46(2):241-50
SDH2-2 protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins Succinate Dehydrogenase Protein Subunits. Plant Mol Biol 2001 May;46(2):241-50
SDH2-1 protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins Succinate Dehydrogenase Protein Subunits. Plant Mol Biol 2001 May;46(2):241-50
ISCA1 protein, human  0   *Iron-Sulfur Proteins *Mitochondrial Proteins. Biochim Biophys Acta. 2004 Aug 2;1700(2):179-88
iscU protein, Entamoeba histolytica  0   *Iron-Sulfur Proteins *Protozoan Proteins Gene Transfer, Horizontal. BMC Evol Biol 2004 Feb 20;4(1):7
iscS protein, Entamoeba histolytica  0   *Iron-Sulfur Proteins *Protozoan Proteins Gene Transfer, Horizontal. BMC Evol Biol 2004 Feb 20;4(1):7
HCF101 protein, Arabidopsis  0   *Iron-Sulfur Proteins *Arabidopsis Proteins. Plant J 2004 Jan;37(2);174-85
AtsB protein, Klebsiella pneumoniae  0   *Iron-Sulfur Proteins. J Bacteriol 1990 Apr;172(4):2131-40
FnrP protein, Paracoccus denitrificans  0   *Bacterial Proteins *Trans-Activators Iron-Sulfur Proteins. Mol Microbiol 1997 Mar;23(5):893-907
SipB protein, Pyrococcus furiosus  EC 1.8.7.-   *Oxidoreductases *Archaeal Proteins Iron-Sulfur Proteins. J Bacteriol 2001 Dec;183(24):7027-36
SipA protein, Pyrococcus furiosus  EC 1.8.7.-   *Membrane Proteins *Oxidoreductases *Archaeal Proteins Iron-Sulfur Proteins. J Bacteriol 2001 Dec;183(24):7027-36
3-chloro-4-hydroxybenzoate reductive dehalogenase  EC 3.8.1.-   *Hydrolases *Iron-Sulfur Proteins Iron-Sulfur Proteins. J Biol Chem 2001 Nov 2;276(44):40991-7
CsmX protein, Chlorobium tepidum  0   *Bacterial Proteins *Iron-Sulfur Proteins. Biochemistry 2001 Jan 16;40(2):464-73
CsmJ protein, Chlorobium tepidum  0   *Bacterial Proteins *Iron-Sulfur Proteins. Biochemistry 2001 Jan 16;40(2):464-73
CsmI protein, Chlorobium tepidum  0   *Bacterial Proteins *Iron-Sulfur Proteins. Biochemistry 2001 Jan 16;40(2):464-73
IscU protein, E coli  0   *Iron-Sulfur Proteins *Escherichia coli Proteins. J Biochem (Tokyo) 1999 Nov;126(5):917-26
nrdG protein, Lactococcus lactis  0   *Bacterial Proteins *Iron-Sulfur Proteins Ribonucleotide Reductases. J Biol Chem 2000 Apr 28;12367-73
shetna protein I  0   *Ferredoxins Iron-Sulfur Proteins. J Biol Inorg Chem 1999 Jun;4(3):311-7
Fdx4 protein, Aquifex aeolicus  0   *Bacterial Proteins *Iron-Sulfur Proteins. Biochem Biophys Res Commun 1999 Aug 11;261(3):885-9
iron hydrogenase  EC 1.12.-   *Hydrogenase *Iron-Sulfur Proteins Bacterial Proteins. J Bacteriol 1999 May;181(9):2947-52
fuscoredoxin protein, Desulfovibrio desulfuricans  0   *Bacterial Proteins *Iron-Sulfur Proteins. J Biol Chem 1992 Mar 5;267(7):4489-96
rnfB protein, Rhodobacter capsulatus  0   *Bacterial Proteins *Iron-Sulfur Proteins. Eur J Biochem 1998 Jan 15;251(1-2):54-64
rnfC protein, Rhodobacter capsulatus  0   *Bacterial Proteins *Iron-Sulfur Proteins. Eur J Biochem 1998 Jan 15;251(1-2):54-64
choline monooxygenase  EC 1.-   *Oxygenases Iron-Sulfur Proteins Plant Proteins. Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3454-8
methanesulfonic acid monooxygenase  EC 1.14.13.-   *Mixed Function Oxygenases Iron-Sulfur Proteins. J Bacteriol 1997 Mar;179(6):1974-9
RdxB protein, Rhodobacter sphaeroides  0   *Bacterial Proteins *Iron-Sulfur Proteins *Membrane Proteins. J Bacteriol 1997 Mar;179(6):1951-61
Dreg-3 protein, Drosophila  0   *Iron-Sulfur Proteins *Drosophila Proteins Circadian Rhythm. Curr Biol 1995 Dec 1;5(12):1424-36
Isf protein, Methanosarcina thermophila  0   *Iron-Sulfur Proteins *Archaeal Proteins. J Biol Chem 1996 Sep 27;271(39):24023-8
acetylene hydratase  EC 4.2.1.-   *Hydro-Lyases Alkynes Iron-Sulfur Proteins Tungsten. J Bacteriol 1995 Oct;177(20):5767-72
FesII protein, Azotobacter vinelandii  0   *Bacterial Proteins *Iron-Sulfur Proteins. Mol Microbiol 1994 Oct;14(1):101-14
HVOR protein, Proteus vulgaris  EC 1.1.-   *Bacterial Proteins *Iron-Sulfur Proteins *Oxidoreductases. Eur J Biochem 1994 Jun 15;222(3):1025-32
heterodisulfide reductase  EC 1.12.99.-   *Oxidoreductases Iron-Sulfur Proteins. Eur J Biochem 1994 Apr 15;221(2):855-61
C/FE-SP protein, Moorella thermoacetica  0   *Bacterial Proteins *Iron-Sulfur Proteins. J Biol Chem Mar 1993 15;268(8):5606-14
prismane protein, Desulfovibrio vulgaris  0   *Bacterial Proteins *Iron-Sulfur Proteins. Eur J Biochem 1992 Jun 15;206(3):697-704
biphenyl-2,3-dioxygenase  EC 1.14.12.18   *Iron-Sulfur Proteins *Oxygenases. J Bacteriol 1992 May;174(9):2903-12
frx B protein, Chlamydomonas reinhardtii  132490-64-3   *Iron-Sulfur Proteins *Plant Proteins. Plant Mol Biol 1990;15(3):449
flavocytochrome c sulfide dehydrogenase  EC 1.8.2.-   *Cytochrome c Group *Oxidoreductases Flavoproteins Iron-Sulfur Proteins Multienzyme Complexes. J Biol Chem 1990;265(17):9793
FNR protein, E coli  0   *Iron-Sulfur Proteins *Escherichia coli Proteins DNA-Binding Proteins Transcription Factors. Mol Microbiol 1989;3(5):593
dimethyl sulfoxide reductase  EC 1.8.99.-   *Iron-Sulfur Proteins *Oxidoreductases Molybdenum. J Bacteriol 1985;162(3):1151
phthalate dioxygenase  EC 1.14.99.-   *Oxygenases Iron-Sulfur Proteins. J Biol Chem 1985;260(6):3251
NADH dehydrogenase (quinone)  EC 1.6.99.5   *Quinone Reductases Iron-Sulfur Proteins. J Biol Chem 1984;259(12):7785
pyruvate formate-lyase activating enzyme  0   *Enzymes Enzyme Activation Iron-Sulfur Proteins. Arch Biochem Biophys 1984;228(1):133
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