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Irritants

More information in Books or onNLM PubMed
Definition: Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.  note X ref COUNTERIRRITANTS but use no qualif with it (i.e., adv eff of a counterirritant is COUNTERIRRITANTS, not COUNTERIRRITANTS /adv eff since this would print as a misleading IRRITANTS /adv eff)   
Examples Tear Gases
Other names Vesicants; Rubefacients; Pustulants; Counterirritants
Substances having this pharmacologic action: teleocidin; dihydroteleocidin B; 12-deoxyphorbolphenylacetate; nickel sulfate; Lugol's solution; omega-Chloroacetophenone; Turpentine; Mechlorethamine; Dinitrochlorobenzene; Cantharidin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Blestre  0   Organic Chemicals Irritants. Aust Vet J 1985;62(1):23
micronomicin  52093-21-7 D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy  *Aminoglycosides Benzalkonium Compounds Irritants Ophthalmic Solutions.
Pharma Action Anti-Bacterial Agents
Antibiotiki 21(11):1033;1976; J Antibiot (Tokyo) 28(1):21;1975; J Jpn Assoc Infect Dis 52(5):146;1978; Jpn J Antibiot 1983;36(1):150; Jpn J Antibiot 30(6):362;1977; Jpn J Antibiot 30(6):386-432;1977; Jpn J Antibiot 31(3):149;1978; Nippon Ganka Gakkai Zasshi 83(5):405;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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