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Isonicotinic Acids

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Definition: Heterocyclic acids that are derivatives of 4-pyridinecarboxylic acid (isonicotinic acid).  hydrazide   
Examples Ethionamide; Iproniazid; Isoniazid; Nialamide; Prothionamide; Pyridoxic Acid 		Other names Acids, Isonicotinic; Acid, Isonicotinic; Isonicotinic Acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide  0   *Isonicotinic Acids *Sulfonamides. J Med Chem 2011 Jan 13;54(1):179-200
3-methoxyisonicotinic acid  0   *Isonicotinic Acids Antioxidants. Arch Pharm Res. 2011 Mar;34(3); 377-82
citrazinic acid  0   *Isonicotinic Acids. Biochem J 2011 Jun 15;436(3):729-39
PHA 408  0   *Indazoles *Isonicotinic Acids. J Pharm Sci 2010 Mar;99(3):1278-87
(isonicotinic acid (2-(4,4,5,5-tetramethyl-(1,3,2)dioxaborolan-2-yl)benzylidene)hydrazide)  0   *Boronic Acids *Isonicotinic Acids. J Inorg Biochem 2008 Dec;102(12):2130-5
3-isonicotinoyl coumarin  0   *Coumarins *Isonicotinic Acids. Spectrochim Acta A Mol Biomol Spectrosc. 2009 Jul;73(1):72-8
sudoterb  0   *Pyrroles *Isonicotinic Acids. Tuberculosis (Edinb) 2008 Mar;88(2):126
2-methyl-3-hydroxy-4-pyridinecarboxylic acid  0   *Isonicotinic Acids. Dalton Trans 2008 Apr 7;(13):1689-97
methyl 3-fluoropyridine-4-carboxylate  0   *Isonicotinic Acids. Molecules 2006;11(2):130-3
3-nitrobenzaldehyde isonicotinoylhydrazone  0   *Hydrazones *Isonicotinic Acids. Acta Crystallogr C 2007 Jan;63(Pt 1):o42-4
2,3-dichlorobenzaldehyde isonicotinoylhydrazone  0   *Hydrazones *Isonicotinic Acids. Acta Crystallogr C 2005 Oct;61(Pt 10):o617-20
2,4-difluorobenzaldehyde isonicotinoylhydrazone  0   *Hydrazones *Isonicotinic Acids. Acta Crystallogr C 2005 Oct;61(Pt 10):o617-20
3-hydroxy-4-pyridinecarboxylic acid  0   *Isonicotinic Acids. Rapid Commun Mass Spectrom 2003;17(18):2039-46
2-fluoroisonicotinic acid hydrazide  0   *Hydrazines *Isonicotinic Acids Fluorine Radioisotopes. Nucl Med Biol 2002 Nov;29(8):817-23
2-methylheptyl isonicotinate  0   *Isonicotinic Acids. Pest Manag Sci 2002 Mar;58(3):297-302
dichlorotetrakis(isonicotinic acid)ruthenium(II)  0   *Isonicotinic Acids *Organometallic Compounds Ruthenium. J Inorg Biochem 2001 Sep;86(2-3):587-94
isonicotinyl 4-nitrophenylcarbonate  0   *Isonicotinic Acids *Nitrobenzenes. J Pept Res 1998 Mar;51(3):188-93
ethyl isonicotinate  1570-45-2   *Isonicotinic Acids. Acta Chem Scand 1995 Mar;49(3):230-2
N(1)-isonicotinoyl-3-methyl-4-(4-hydroxybenzilidene)-2-pyrazolin-5-one  103847-83-2   *Isonicotinic Acids *Pyrazolones Copper. J Chem Technol Biotechnol 1993;57(1):43-7
2,6-dichloroisonicotinic acid  5398-44-7   *Isonicotinic Acids. Plant Cell 1992 Jun;4(6):645-56
isocantleyine  143564-04-9   *Isonicotinic Acids *Terpenes Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1992;27(2):113-6
2,6-bis(4-chlorophenyl)-4-pyridinecarboxylic acid  33565-60-5   *Isonicotinic Acids. Toxicol Pathol 1992;20(1):7-17
methyl 2-iodoisonicotinate  134579-47-8   *Isonicotinic Acids. Int J Rad Appl Instrum (A) 1991;42(3):215
1-isonicotinyl-2-palmitoyl hydrazine  101524-04-3   *Hydrazines *Isonicotinic Acids *Palmitic Acids. Antimicrob Agents Chemother 1990;34(11):2061
3-amino-2-piperidone-6-carboxylic acid  42155-74-8   *Isonicotinic Acids. Int J Pept Protein Res 1989;34(4):311
inabenfide  82211-24-3   *Isonicotinic Acids. Xenobiotica 1987;17(8):925
2-hydroxyisonicotinic acid N-oxide  13602-64-7 4-Pyridinecarboxylic acid, 2-hydroxy-, 1-oxide  *Isonicotinic Acids. J Biol Chem 1982;257(21):12746
isoarecaidine propyl ester  77035-54-2   *Isonicotinic Acids. Eur J Pharmacol 1982;77(1):49
isoguvacine propyl ester  81256-84-0 4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-, propyl ester  *Isonicotinic Acids. Eur J Pharmacol 1982;77(1):49
1-butyl-isonicotinoylpiperidine  77954-39-3 4-pyridinecarboxamide, N-(1-butyl-4-piperidinyl)-, dihydrochloride  *Isonicotinic Acids. Pol J Pharmacol Pharm 1980;32(1):141
1-butyl-4-phenyl-4-isonicotinoylaminoethylpiperidine  59455-24-2 4-pyridinecarboxamide, N-((1-butyl-4-phenyl-4-piperidinyl)methyl)  *Isonicotinic Acids. Pol J Pharmacol Pharm 1980;32(1):141
N-methylisoguvacine  68947-50-2   *Isonicotinic Acids. Experientia 34(9):1193;1978
isonicotinyloxycarbonyl  0   *Isonicotinic Acids. J Org Chem 42(20):3286;1977
isoguvacine  64603-90-3 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid  *Isonicotinic Acids.
Pharma Action GABA Agonists 		Eur J Pharmacol 1979;58(4):485; Experientia 34(9):1193;1978; Nature 268(6515):53;1977
isonicotinuric acid  2015-20-5 N-(4-pyridinylcarbonyl)glycine  *Isonicotinic Acids. J Pharmacokinet Biopharm 46(3):211;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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