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Killer Cells, Natural

More information in Books or onNLM PubMed
Definition: Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.  do not confuse with NATURAL KILLER T-CELLS; if subpopulations are discussed, coordinate IM with LYMPHOCYTE SUBSETS (IM)   
See Also Receptors, Natural Killer Cell
Examples Killer Cells, Lymphokine-Activated 		Other names Natural Killer Cells; NK Cells; Natural Killer Cell; NK Cell; Killer Cell, Natural; Cells, Natural Killer; Cells, NK; Cell, Natural Killer; Cell, NK
 
SubstanceCAS Registry & nameCategoriesSource
NKR-P1A protein, rat  0   *Receptors, Immunologic Killer Cells, Natural. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4645-8
Ncr1 protein, rat  0   *Natural Cytotoxicity Triggering Receptor 1 Killer Cells, Natural. J Leukoc Biol. 2004 Dec;76(6):1200-6
Hcst protein, mouse  0   *Receptors, Immunologic Killer Cells, Natural.
Nktr protein, mouse  0   *Receptors, Immunologic Killer Cells, Natural.
NKR-P1B protein, rat  0   *Receptors, Immunologic Killer Cells, Natural. Int Immunol 2003 Mar;15(3):411-6
KIR2DS4 protein, human  0   *Receptors, KIR Killer Cells, Natural. Tissue Antigens 2002 Sep;60(3):254-8
KIR2DS2 protein, human  0   *Receptors, KIR Killer Cells, Natural. Blood 2001 Aug 1;98(3):705-13
p62 natural killer cell receptor  0   *Receptors, Immunologic Killer Cells, Natural. Annu Rev Immunol 2001;19:291-330
NCR3 protein, human  0   *Natural Cytotoxicity Triggering Receptor 3 Killer Cells, Natural. Annu Rev Immunol 2001;19:197-223
Ly-49W1 receptor  0   *Antigens, Ly Killer Cells, Natural. J Immunol 2001 Feb 15;166(4):2333-41
Ly-49W2 receptor  0   *Antigens, Ly Killer Cells, Natural. J Immunol 2001 Feb 15;166(4):2333-41
Ly-49W receptor  0   *Antigens, Ly Killer Cells, Natural. J Immunol 2001 Feb 15;166(4):2333-41
B-NK1 protein, Gallus gallus  0   *Receptors, Immunologic Killer Cells, Natural. Nature 1999 Oct 28;401(6756):923-5
NK lytic-associated molecule  0   *Membrane Proteins Killer Cells, Natural Zinc Fingers Ubiquitin-Protein Ligases. J Immunol 1999 Aug 15;163(4):1775-85
HCST protein, human  0   *Receptors, Immunologic Killer Cells, Natural. J Immunol 1999 Nov 1;163(9):4651-4; Science 1999 Jul 30;285(5428):730-2
Ncr1 protein, mouse  0   *Antigens, Ly *Natural Cytotoxicity Triggering Receptor 1 Killer Cells, Natural. Eur J Immunol 1999 Mar;29(3):1014-20
NKR-P2 protein, rat  0   *Receptors, Immunologic *Lectins, C-Type Killer Cells, Natural. Int Immunol 1998 Apr;10(4):379-85
NCR1 protein, human  0   *Natural Cytotoxicity Triggering Receptor 1 Killer Cells, Natural. Eur J Immunol 1998 May;28(5):1611-6
nonspecific cytotoxic cell receptor protein 1  0   *Receptors, Antigen Killer Cells, Natural. Mol Immunol 1997 Aug-Sep;34(12-13):955-65
TYROBP protein, human  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing Killer Cells, Natural Receptors, Natural Killer Cell. Genomics. 1998 Dec 1;54(2):307-15.; Nature 1998 Feb 12;391(6668):703-7
LOC133728 protein, human  0   *Neoplasm Proteins *Receptors, Cell Surface Killer Cells, Natural. J Exp Med 1997 May 19;185(10):1735-42
NK cell receptor KIR103AS  0   *Receptors, Immunologic Killer Cells, Natural. Tissue Antigens 1996 Oct;48(4 Pt 1):285-95
p70 natural killer cell receptor  0   *Receptors, Immunologic Killer Cells, Natural. Proc Natl Acad Sci U S A 1996 Feb 20;93(4):1453-7
p50 natural killer cell receptor  0   *Receptors, Immunologic Killer Cells, Natural. J Exp Med 1996 Feb 1;183(2):645-50
NKTR protein, human  0   *Receptors, Immunologic Killer Cells, Natural. Genomics 1993 May;16(2):548-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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