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Kynurenic Acid
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Definition
: A broad-spectrum excitatory amino acid antagonist used as a research tool.
Pharmacological Action
Excitatory Amino Acid Antagonists
Other names
Acid, Kynurenic; Kynurenate
Substance
CAS Registry & name
Categories
Source
Drugs
*
2-
(2-
N,N-
dimethylaminoethylamine-
1-
carbonyl)-
1H-
quinolin-
4-
one hydrochloride
0
Kynurenic Acid/*analogs & derivatives.
J Neural Transm. 2010 Feb;117(2):183-8
3-
(2'-
pyrrolidinyl)-
kynurenic acid
0
*Pyrrolidines
Kynurenic Acid/*analogs & derivatives.
Magn Reson Chem. 2009 May;47(5):456-9
3-
hydroxyquinaldic acid
0
Kynurenic Acid/*analogs & derivatives.
Mol Biosyst. 2008 Jun;4(6):622-8
SZR 72
0
Kynurenic Acid/*analogs & derivatives.
Neurosci Res 2008 Aug;61(4):429-32
6-
hydroxykynurenic acid
0
Kynurenic Acid/*analogs & derivatives.
J Neurochem 2001 May;77(4):1108-15
4-
quinolone-
2-
carboxylic acid
0
*Kynurenic Acid.
J Nat Prod 1998 Feb;61(2):262-3
7-
chloro-
5-
iodokynurenic acid
0
Kynurenic Acid/*analogs & derivatives
Iodine Radioisotopes.
Appl Radiat Isot 1997 Sep;48(9):1173-7
4,6-
dichlorokynurenine
0
Kynurenic Acid/*analogs & derivatives.
Neuroreport 1996 Dec 20;8(1):15-8
7-
chlorothiokynurenic acid
135025-56-8
Kynurenic Acid/*analogs & derivatives.
J Pharmacol Exp Ther 1993 Nov;267(2):937-41
5-
chlorothiokynurenic acid
136036-87-8
Kynurenic Acid/*analogs & derivatives.
J Pharmacol Exp Ther 1993 Nov;267(2):937-41
thiokynurenate
135025-53-5
Kynurenic Acid/*analogs & derivatives.
Pharmacol Res 1992 Feb-Mar;25(Suppl 1):33-4
5,7-
dichlorokynurenic acid
131123-76-7
Kynurenic Acid/*analogs & derivatives.
Pharma Action
Excitatory Amino Acid Antagonists
Mol Pharmacol 1990;38(4):554
7-
chlorokynurenic acid
18000-24-3
Kynurenic Acid/*analogs & derivatives
Receptors, Glycine/antagonists & inhibitors.
Pharma Action
Excitatory Amino Acid Antagonists
;
Neuroprotective Agents
Proc Natl Acad Sci USA 1988;85(17):6547
4,6,8-
trihydroxyquinaldic acid
0
Kynurenic Acid/*analogs & derivatives.
Wakayama Med Rep 14(4):139;1971