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L-Lactate Dehydrogenase

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Definition: A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.      Other names Lactate Dehydrogenase; L Lactate Dehydrogenase; Dehydrogenase, Lactate; Dehydrogenase, L-Lactate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dicholesteroyl diselenide  0   *Organoselenium Compounds Cholesterol/*analogs & derivatives L-Lactate Dehydrogenase/antagonists & inhibitors. Toxicol In Vitro 2009 Feb;23(1):14-20
Lactate dehydrogenase deficiency type A  0   *Glycogen Storage Disease L-Lactate Dehydrogenase/deficiency.
lactate dehydrogenase 4  EC 1.1.1.27   *L-Lactate Dehydrogenase Isoenzymes.
lactate dehydrogenase 3  EC 1.1.1.27   Isoenzymes *L-Lactate Dehydrogenase.
lactate dehydrogenase 2  EC 1.1.1.27   *L-Lactate Dehydrogenase Isoenzymes.
lactate dehydrogenase-K  EC 1.1.1.27   *L-Lactate Dehydrogenase Isoenzymes.
lactate dehydrogenase C4  EC 1.1.1.27.-   *L-Lactate Dehydrogenase Isoenzymes.
lactate dehydrogenase 5  EC 1.1.1.27.-   *L-Lactate Dehydrogenase Isoenzymes.
lactate dehydrogenase 1  EC 1.1.1.27.-   *L-Lactate Dehydrogenase Isoenzymes.
8-deoxyhemigossylic acid  0   *Sesquiterpenes L-Lactate Dehydrogenase/antagonists & inhibitors. J Med Chem 1998 Sep 24;41(20):3879-87
lldD protein, E coli  EC 1.1.2.3   *Flavoproteins *L-Lactate Dehydrogenase *Escherichia coli Proteins. J Bacteriol 1993 Oct;175(20):6671-8
KC 764  94457-09-7   *Bicyclo Compounds *Nicotinic Acids Aspartate Aminotransferases/antagonists & inhibitors Creatine Kinase/antagonists & inhibitors L-Lactate Dehydrogenase/antagonists & inhibitors. Arzneimittelforschung 1992 Jan;42(1):32-9
ethyl N-benzyl-N-methyloxamate  128429-34-5   Oxamic Acid/*analogs & derivatives L-Lactate Dehydrogenase/antagonists & inhibitors. Arzneimittelforschung 1990;40(5):607
asp56-LDH(K)  0   *Antigens, Viral, Tumor *Retroviridae Proteins, Oncogenic Harvey murine sarcoma virus Kirsten murine sarcoma virus L-Lactate Dehydrogenase. Transplant Proc 1984;16(2):449

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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