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Levamisole

More information in Books or onNLM PubMed
Definition: An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)     
Pharmacological Action Adjuvants, Immunologic; Antinematodal Agents; Antirheumatic Agents 		Other names Levotetramisole; L-Tetramisole; Hydrochloride, Levamisole; Solaskil; Levamisole Hydrochloride; Dekaris; DecarisDrugs* : ERGAMISOL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Algalev  0   *gamma-Globulins *Levamisole *Serum Albumin, Bovine Drug Combinations. Vet Med (Praha) 1989;34(12):705
3-aminolevamisole  43081-63-6   Levamisole/*analogs & derivatives. Mol Pharmacol 1987;31(2):185
4-hydroxylevamisole  69359-04-2 Phenol, 4-(2,3,5,6-tetrahydroimidazo(2,1-b)thiazol-6-yl)-, (S)  Levamisole/*analogs & derivatives. Biopharm Drug Dispos 1986;7(1):71
meitonii  82534-62-1   Levamisole/*analogs & derivatives. Lab Delo 1985;(3):169
kamizol  97123-80-3 Kamizol  Levamisole/*analogs & derivatives. Lab Delo 1985;(3):169
Helmoral B  77482-46-3 Phenol, 2,2'-thiobis(4,6-dichloro-, mixt. with (S)-2,3,5,6-tetrahydro-6-phenylimidazo(2,1-b)thiazole  *Bithionol *Levamisole Drug Combinations. Bull Anim Health Prod Afr 26(3):242;1978
4-bromotetramisole  6646-46-4   Tetramisole/*analogs & derivatives Levamisole/analogs & derivatives.
Pharma Action Anthelmintics 		Acta Odontol Scand 33(3):143;1976; Biochem Pharmacol 24:1175;1975; Clin Chem 23(3):454;1977; Experientia 33(2):154;1977; Histochemistry 44(3):277;1975; Infect Immun 23(1):94;1979; J Clin Chem Clin Biochem 1979;17(9):605; J Histochem Cytochem 21(9):812;1973; J Histochem Cytochem 26(5):359;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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