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Dihydrolipoamide Dehydrogenase

More information in Books or onNLM PubMed
Definition: A flavoprotein containing oxidoreductase that catalyzes the reduction of lipoamide by NADH to yield dihydrolipoamide and NAD+. The enzyme is a component of several MULTIENZYME COMPLEXES.      Other names NADH Diaphorase; NAD Diaphorase; Lipoamide Dehydrogenase; Glycine Decarboxylase Complex L Protein; Diaphorase, NADH; Diaphorase, NAD; Dehydrogenase, Valine Lipoamide; Dehydrogenase, Lipoyl; Dehydrogenase, Lipoic Acid; Dehydrogenase, Lipoamide; Dehydrogenase, Dihydrolipoyl; Dehydrogenase, Dihydrolipoamide; Valine Lipoamide Dehydrogenase; Lipoyl Dehydrogenase; Lipoic Acid Dehydrogenase; Lipoamide Dehydrogenase, Valine; L-Protein, Glycine Decarboxylase Complex; Glycine Decarboxylase Complex L-Protein; Dihydrolipoyl Dehydrogenase; Diaphorase (Lipoamide Dehydrogenase)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,3-diphenyl-1,4-naphthoquinone  0   *Naphthoquinones Dihydrolipoamide Dehydrogenase/antagonists & inhibitors. J Parasitol 2009 Apr;95(2):461-6
lpd protein, E coli  EC 1.8.1.-   *Dihydrolipoamide Dehydrogenase *Escherichia coli Proteins. Mol Microbiol 1994 Apr;12(1):95-104
4-aminophenyldichloroarsine  5410-78-6   *Arsenicals Dihydrolipoamide Dehydrogenase/antagonists & inhibitors. Biochem J 1987;243(3):661
methanearsonous acid  25400-23-1   *Arsenicals Dihydrolipoamide Dehydrogenase/antagonists & inhibitors. Arch Biochem Biophys 1985;142(1):1
phenylarsonous acid  25400-22-0   *Arsenicals Dihydrolipoamide Dehydrogenase/antagonists & inhibitors. Arch Biochem Biophys 1985;242(1):1

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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