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Lipoproteins, HDL

More information in Books or onNLM PubMed
Definition: A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.  hyperalphalipoproteinemia   
See Also Tangier Disease
Examples Cholesterol, HDL; High-Density Lipoproteins, Pre-beta; Lipoproteins, HDL2; Lipoproteins, HDL3
Other names alpha-Lipoproteins; High-Density Lipoproteins; alpha Lipoproteins; Lipoproteins, High-Density; Lipoproteins, Heavy; High Density Lipoproteins; HDL Lipoproteins; alpha-1 Lipoprotein; Heavy Lipoproteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
APOL4 protein, human  0   *Apolipoproteins *Lipoproteins, HDL. J Lipid Res 2001 Apr;42(4):620-30
APOL2 protein, human  0   *Apolipoproteins *Lipoproteins, HDL. J Lipid Res 2001 Apr;42(4):620-30
TLF1 protein, human  0   *Lipoproteins, HDL. J Biol Chem 2001 Aug 10;276(32):30254-60
APOL1 protein, human  0   *Apolipoproteins *Lipoproteins, HDL. J Biol Chem 1997 Oct 10;272(41):25576-82
high density lipoprotein-binding protein, rat  0   *DNA-Binding Proteins *Membrane Proteins Lipoproteins, HDL. Endocrinology 1994 Jun;134(6):2360-6
apoHDL-sepharose  0   *Apolipoproteins *Lipoproteins, HDL Sepharose/*analogs & derivatives. Bioorg Khim 1992 Sep;18(9):1214-20
HDL cholesteryl ester  0   *Cholesterol Esters *Lipoproteins, HDL. J Biol Chem 1989;264(14):8141
glycosylated lipoproteins, HDL  0   *Lipoproteins, HDL Glycosylation. Ter Arkh 1986;58(11):106
apolipoprotein A-II isoproteins, human  0   *Apolipoprotein A-II Lipoproteins, HDL. J Lipid Res 1983;24(8):1021
high density lipoprotein phosphatidylcholine  0   *Lipoproteins, HDL *Phosphatidylcholines. J Clin Chem Clin Biochem 1983;21(3):145
high density lipoprotein sphingomyelin  0   *Lipoproteins, HDL *Sphingomyelins. J Clin Chem Clin Biochem 1983;21(3):139
high density lipoprotein-1  0   *Lipoproteins, HDL. J Lipid Res 1982;23(6):903
HDL-triglyceride  0   *Lipoproteins, HDL *Triglycerides. Clin Nephrol 1982;17(4):191
high density lipoprotein receptors  0   *Lipoproteins, HDL *Receptors, Lipoprotein. Endocrinology 1981;109(3):783
apolipoprotein S-peptides  0   *Apolipoproteins *Lipoproteins, HDL. Clin Chim Acta 1981;111(2-3):267
very high density lipoproteins  0   *Lipoproteins, HDL. Biokhimiia 1980;45(7):1208
apolipoprotein E-rich HDL  0   *Apolipoproteins E *Lipoproteins, HDL. J Biol Chem 1980;255(11):5454

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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