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Lobeline

More information in Books or onNLM PubMed
Definition: An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.  /biosyn permitted if by plant   
Pharmacological Action Ganglionic Stimulants; Nicotinic Agonists; Respiratory System Agents 		Other names Sulfate, Lobeline; Smokeless; Lobeline Sulfate; Inibsa Brand of Lobelin Sulfate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
lobelanidine  0   Lobeline/*analogs & derivatives. Bioorg Med Chem. 2009 Mar 1;17(5):1837-9
lobelane  0   Lobeline/*analogs & derivatives. Bioorg Med Chem Lett 2008 Dec 15;18(24):6509-12
CRM I-32-1  0   Lobeline/*analogs & derivatives. Neuropharmacology 1998;37(1):93-102
CRM I-13-1  0   Lobeline/*analogs & derivatives. Neuropharmacology 1998;37(1):93-102

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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