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Lymphocyte Depletion

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Definition: Immunosuppression by reduction of circulating lymphocytes or by T-cell depletion of bone marrow. The former may be accomplished in vivo by thoracic duct drainage or administration of antilymphocyte serum. The latter is performed ex vivo on bone marrow before its transplantation.      Other names Depletion, Lymphocyte
 
SubstanceCAS Registry & nameCategoriesSource
FN18-CRM9  0   *Antibodies, Monoclonal *Diphtheria Toxin Recombinant Fusion Proteins Immunotoxins Graft Rejection Lymphocyte Depletion. Transplant Proc 1998 Aug;30(5):2150-1

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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