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Lymphocyte Activation

More information in Books or onNLM PubMed
Definition: Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.  lymphocyte transformation test goes here but do not index under specific agent inducing transformation unless particularly discussed; do not use for neoplastic transformation of lymphocytes (   
See Also Blast Crisis 		Other names Lymphocyte Transformation; Lymphocyte Stimulation; Lymphoblast Transformation; Blastogenesis; Blast Transformation; Stimulation, Lymphocyte; Activation, Lymphocyte; Transformation, Lymphocyte; Transformation, Lymphoblast; Transformation, Blast
 
SubstanceCAS Registry & nameCategoriesSource
CD100 antigen  0   *Antigens, CD *Semaphorins Antigens, Differentiation, T-Lymphocyte Lymphocyte Activation. Int Immunol 1995 Jan;7(1):1-8
CD223 antigen  0   *Antigens, CD Lymphocyte Activation. J Exp Med 1992 Aug 1;176(2):327-37
MLR3 activation antigen  0   *Antigens, Surface *Receptors, Antigen, T-Cell Lymphocyte Activation. Eur J Immunol 1989;19(2):323
CD69 antigen  0   *Antigens, Differentiation, T-Lymphocyte *Antigens, CD *Lectins, C-Type Lymphocyte Activation. J Exp Med 1988;167(5):1572
GP 40-80 glycoprotein, human  0   *Antigens, Surface *Membrane Glycoproteins Lymphocyte Activation. Acta Pathol Microbiol Immunol Scand (C) 1986;94(5):181
thymocyte-activating factor, fibroblasts  0   *Cytokines Fibroblasts Lymphocyte Activation. Infect Immun 1987;55(4):947
lymphocyte proliferation potentiating factors  0   *Lymphokines Interleukins Lymphocyte Activation. Immunology 1984;53(4):683
nordimaprit  17124-82-2   Dimaprit/*analogs & derivatives Lymphocyte Activation/drug effects. Br J Pharmacol 1984;83(1):293
4-acetamidobenzoic acid  556-08-1   4-Aminobenzoic Acid/*analogs & derivatives Lymphocyte Activation. Xenobiot 1(2):121;1971
concanavalin A-induced helper factors  0   *Lymphokines Concanavalin A Dexamethasone Lymphocyte Activation. Eur J Immunol 9(7):546;1979

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