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Lymphotoxin-alpha

More information in Books or onNLM PubMed
Definition: A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.  for "lymphocytotoxin" use CYTOTOXINS and LYMPHOCYTES    Other names Tumor Necrosis Factor-beta; Tumor Necrosis Factor Ligand Superfamily Member 1; TNF-beta; TNF Superfamily, Member 1; Lymphotoxin; alpha Lymphotoxin; Tumor Necrosis Factor beta; Soluble Lymphotoxin alpha; Lymphotoxin-alpha, Soluble; Lymphotoxin alpha3; Lymphotoxin alpha; alpha-Lymphotoxin; Lymphotoxin-alpha3; Soluble Lymphotoxin-alpha
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
mutein 2  0   *Lymphotoxin-alpha *Recombinant Proteins. Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3324-9
C9RP protein, human  0   *Lymphotoxin-alpha. Proc Natl Acad Sci USA 1986;83(14):5262
anti-treponemal lymphotoxin  0   *Lymphotoxin-alpha Treponema pallidum. Arch Immunol Ther Exp (Warsz) 1984;32(1):29
lymphocyte effector molecules  0   *Lymphotoxin-alpha. Cell Immunol 24(2):277;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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