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Mannose-6-Phosphate Isomerase

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Definition: An enzyme that catalyzes the reversible isomerization of D-mannose-6-phosphate to form D-fructose-6-phosphate, an important step in glycolysis. EC 5.3.1.8.      Other names Phosphomannose Isomerase; Mannosephosphate Isomerase; Mannose 6 Phosphate Isomerase; Isomerase, Phosphomannose; Isomerase, Mannosephosphate; Isomerase, Mannose-6-Phosphate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-phospho-D-arabinonhydrazide  0   *Hydrazines *Sugar Phosphates Mannose-6-Phosphate Isomerase/antagonists & inhibitors. Proteins. 2011 Jan;79(1):203-20
6-deoxy-6-dicarboxymethylmannose  0   *Uronic Acids Mannose-6-Phosphate Isomerase/antagonists & inhibitors. Bioorg Med Chem 2009 Oct 15;17(20):7100-7
Congenital disorder of glycosylation type 1B  0   *Congenital Disorders of Glycosylation Mannose-6-Phosphate Isomerase/deficiency.
AF 14049  0   *Amides *Indans Mannose-6-Phosphate Isomerase/antagonists & inhibitors. Bioorg Med Chem Lett 1998 Sep 8;8(17):2303-8
WbpW protein, Pseudomonas aeruginosa  0   *Bacterial Proteins *Multienzyme Complexes Mannose-6-Phosphate Isomerase Nucleotidyltransferases. Mol Microbiol 1998 Sep;29(6):1419-34
ManB protein, bacteria  EC 2.7.7.-   *Bacterial Proteins *Mannose-6-Phosphate Isomerase *Multienzyme Complexes *Nucleotidyltransferases. Int J Biol Macromol 1994 Dec;16(6):287-9
dTDP-D-glucose synthase  EC 2.7.7.-   *Mannose-6-Phosphate Isomerase *Nucleotidyltransferases ATP-Binding Cassette Transporters. J Bacteriol 1994 Jan;176(1):92-9
phosphomannose isomerase-guanosine diphospho-D-mannose pyrophosphorylase  134688-81-6   *Bacterial Proteins *Mannose-6-Phosphate Isomerase *Multienzyme Complexes *Nucleotidyltransferases. Biochim Biophys Acta 1993 Mar 20;1172(3):329-31

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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