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Mast Cells

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Definition: Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.  MAST-CELL DISEASE see MASTOCYTOSIS is available    Other names Basophils, Tissue; Tissue Basophils; Tissue Basophil; Mast Cell; Cells, Mast; Cell, Mast; Basophil, Tissue
 
SubstanceCAS Registry & nameCategoriesSource
chymase 2  EC 3.4.21.-   *Chymases Mast Cells. J Immunol 1993 Sep 15;151(6):3206-14
mast cell protease-like  EC 3.4.21.-   *Serine Endopeptidases Mast Cells. J Biol Chem 1991;266(3):1934
mast cell protease 4  EC 3.4.21.-   *Serine Endopeptidases Mast Cells. J Biol Chem 1991;266(3):1934

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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