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Melanoma

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Definition: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)  /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM); MELANOMA, EXPERIMENTAL is also available   
Examples Hutchinson's Melanotic Freckle; Melanoma, Amelanotic; Melanoma, Experimental
Other names Malignant Melanoma; Melanomas, Malignant; Melanomas; Melanoma, Malignant; Malignant Melanomas
 
SubstanceCAS Registry & nameCategoriesSource
cis-dichlorobis(3,4,7,8-tetramethyl-1,10-phenanthroline)rhodium(III) chloride  0   *Organometallic Compounds Antineoplastic Agents Melanoma/drug therapy Rhodium. Anticancer Drugs. 2011 Oct;22(9):896-904
Uveal melanoma  0   *Melanoma *Uveal Neoplasms.
Primary malignant melanoma of the cervix  0   *Uterine Cervical Neoplasms *Melanoma.
Melanoma astrocytoma syndrome  0   *Astrocytoma *Melanoma *Nervous System Neoplasms.
antigen LG2-C, human  0   *Antigens, Neoplasm Melanoma. Cancer Immun 2002 Jul 19;2:9
Canvaxin  0   *Cancer Vaccines Melanoma. J Clin Oncol 2002 Aug 1;20(15):3242-8
melanoma-associated cell surface protein, 55-kDa, human  0   *Antigens, Neoplasm *Cell Adhesion Molecules Melanoma. Cancer Res 2000 Oct 15;60(20):5848-56
GSDMC protein, human  0   *DNA-Binding Proteins *Tumor Markers, Biological Melanoma Leucine Zippers. Jpn J Cancer Res 2001 Feb;92(2):140-51
AIM2 protein, human  0   *Nuclear Proteins Melanoma. FEBS Lett 2000 May 26;474(1):38-42
HMW-MAA  0   *Antigens, Neoplasm Melanoma. Cancer Immunol Immunother 2000 Mar;48(12);691-702
Melacine  0   *Cancer Vaccines Melanoma Immunotherapy, Active. Semin Oncol 1998 Dec;25(6):623-35
tumor-associated antigen, gp43  0   *Antigens, Neoplasm Melanoma. Cell Immunol 1997 Jun 15;178(2):162-71
GAGE2A protein, human  0   *Antigens, Neoplasm *Neoplasm Proteins Melanoma. J Exp Med 1995 Sep 1;182(3):689-98
GAGE1 protein, human  0   *Antigens, Neoplasm *Neoplasm Proteins Melanoma. J Exp Med 1995 Sep 1;182(3):689-98
polyvalent melanoma cell vaccine  0   *Cancer Vaccines Melanoma Immunotherapy, Adoptive. J Thorac Cardiovasc Surg 1995 Jul;110(1):119-28
9-O-acetyl-GD3 ganglioside  98743-26-1   *Gangliosides Antigens, Neoplasm Melanoma. J Biol Chem 1985;260(27):14556
dopachrome isomerase  EC 5.3.3.12   *Intramolecular Oxidoreductases Antigens, Neoplasm Melanoma. J Invest Dermatol 1984;83(2):145

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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