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Membrane Proteins

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Definition: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.  /biosyn /drug eff /physiol /ultrastruct permitted   
Examples 5-Lipoxygenase-Activating Proteins; Amyloid beta-Protein Precursor; Ankyrins; Arrestins; B7 Antigens; Bacterial Outer Membrane Proteins; Calnexin; Chemokine CX3CL1; Claudins; Cornified Envelope Proline-Rich Proteins; Dystrophin; Dystrophin-Associated Proteins; Electron Transport Chain Complex Proteins; Ephrins; gp100 Melanoma Antigen; Heterotrimeric GTP-Binding Proteins; LDL-Receptor Related Protein-Associated Protein; Lipid-Linked Proteins; Matrix Metalloproteinases, Membrane-Associated; Membrane Fusion Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Myelin Proteins; Neurofibromin 2; Phospholipid Transfer Proteins; Pore Forming Cytotoxic Proteins; Presenilins; Protoporphyrinogen Oxidase; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Receptor Activity-Modifying Proteins; Receptor-Like Protein Tyrosine Phosphatases; Receptors, Cell Surface; Spectrin; Tetraspanins; Thylakoid Membrane Proteins; Utrophin; Vesicular Transport Proteins 		Other names Surface Proteins; Integral Membrane Proteins; Cell Surface Proteins; Cell Membrane Proteins; Proteins, Surface; Proteins, Membrane-Associated; Proteins, Membrane; Proteins, Integral Membrane; Proteins, Cell Surface; Proteins, Cell Membrane; Protein, Membrane; Protein, Integral Membrane; Membrane Proteins, Integral; Membrane Protein, Integral; Membrane Associated Proteins; Membrane-Associated Proteins; Membrane Protein; Integral Membrane Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NECC1 protein, rat  0   *Membrane Proteins. Biochem J. 2012 Apr 15;443(2):387-96.
OZF2 protein, Arabidopsis  0   *Carrier Proteins *Arabidopsis Proteins Membrane Proteins Zinc Fingers. Plant Cell Physiol. 2012 Jan;53(1):193-203.
Dsc5 protein, S pombe  0   *Carrier Proteins *Membrane Proteins *Schizosaccharomyces pombe Proteins. J Biol Chem. 2012 Jan 2;287(1):672-81
TMEM207 protein, human  0   *Carrier Proteins *Membrane Proteins Neoplasm Proteins. Carcinogenesis. 2012 Mar;33(3):548-54.
dusky-like protein, Drosophila  0   *Membrane Proteins *Drosophila Proteins. Development. 2012 Mar;139(5):906-16.
TECPR1 protein, human  0   *Membrane Proteins. Mol Cell. 2012 Mar 9;45(5):629-41
OCTOPUS protein, Arabidopsis  0   *Membrane Proteins *Arabidopsis Proteins. Development. 2012 Apr;139(7):1306-15.
MgrB protein, E coli  0   *Membrane Proteins *Escherichia coli Proteins. J Bacteriol. 2012 Mar;194(6):1457-63.
Megf11 protein, mouse  0   *Membrane Proteins. Nature. 2012 Mar 22;483(7390):465-9
FXYD5 protein, rat  0   *Membrane Proteins. Int J Mol Med. 2012 Feb;29(2):231-8.
CDC50A protein, mouse  0   *Membrane Proteins. J Histochem Cytochem. 2012 Mar;60(3):205-18
WaaL protein, E coli  EC 6.1.-   *Carbon-Oxygen Ligases *Escherichia coli Proteins Membrane Proteins. Mol Microbiol. 2008 Dec;70(6):1424-40.
Myadml2 protein, rat  0   *Membrane Proteins.
Myadml2 protein, mouse  0   *Membrane Proteins.
MYADML2 protein, human  0   *Membrane Proteins.
OPN5 protein, mouse  0   *Membrane Proteins *Opsins. FEBS Lett. 2003 Nov 20;554(3):410-6.
OPN5 protein, human  0   *Opsins *Membrane Proteins. FEBS Lett. 2003 Nov 20;554(3):410-6.
Gsf2 protein, S pombe  0   *Membrane Proteins *Schizosaccharomyces pombe Proteins. Mol Microbiol. 2011 Dec;82(6):1531-44
autophagy-related protein 2 homolog A, human  0   *Membrane Proteins. Acta Biochim Pol. 2011;58(3):365-74.
LrgB protein, Arabidopsis  0   *Membrane Proteins *Arabidopsis Proteins Chloroplasts. New Phytol. 2012 Jan;193(1):81-95
FUNDC1 protein, human  0   *Membrane Proteins *Mitochondrial Proteins. Nat Cell Biol. 2012 Feb;14(2):177-85
C9orf123 protein, human  0   *Membrane Proteins. Oncogene. 2012 Jan 19;31(3):333-41.
Asrij protein, Drosophila  0   *Membrane Proteins *Drosophila Proteins. Dev Genes Evol. 2003 Apr;213(3):134-7.
FKBP15 protein, human  0   *Membrane Proteins. Biochem J. 2012 Feb 15;442(1):209-20.
TM4SF5 protein, mouse  0   *Membrane Proteins. J Clin Invest. 2008 Apr;118(4):1354-66.
AMIGO protein, mouse  0   *Membrane Proteins. EMBO Rep. 2011 Dec;12(12):1293-9
Neph3 protein, zebrafish  0   *Membrane Proteins *Zebrafish Proteins. Differentiation. 2012 Jan;83(1):38-46
TMEM16J protein, human  0   *Membrane Proteins. J Infect Dis. 2012 Feb;205(4); 586-94
C12orf62 protein, human  0   *Membrane Proteins *Mitochondrial Proteins. Am J Hum Genet. 2012 Jan 13;90(1):142-51.
TMEM138 protein, human  0   *Membrane Proteins. Science. 2012 Feb 24;335(6071):966-9.
ATAD3C protein, human  EC 3.6.1.-   *Adenosine Triphosphatases *Membrane Proteins *Mitochondrial Proteins. Med Sci (Paris). 2011 Dec;27(12):1089-95
pecanex protein, Drosophila  0   *Membrane Proteins *Drosophila Proteins. Development. 2012 Feb;139(3):558-67.
OZF1 protein, Arabidopsis  0   *Membrane Proteins *Arabidopsis Proteins Zinc Fingers Oxidative Stress. J Plant Res. 2011 Nov;124(6):699-705
FAD158 protein, mouse  0   *Membrane Proteins. J Biol Chem. 2004 Aug 13;279(33):34840-8.
Tmbim3 protein, mouse  0   *Membrane Proteins *Nerve Tissue Proteins. Mol Cell Biochem. 2011 Nov;357(1-2):73-81.
CJD1 protein, Arabidopsis  0   *Membrane Proteins *Arabidopsis Proteins Chloroplast Proteins. PLoS One. 2011;6(10):e25368.
ARC2 protein, human  EC 1.-   *Membrane Proteins *Oxidoreductases Mitochondrial Proteins. Eukaryot Cell. 2011 Oct;10(10):1270-82.
DMA-1 protein, C elegans  0   *Membrane Proteins *Caenorhabditis elegans Proteins. Nat Neurosci. 2012 Jan;15(1):57-63
TMEM237 protein, human  0   *Membrane Proteins. Am J Hum Genet. 2011 Dec 9;89(6); 713-30
At1g51800 protein, Arabidopsis  EC 2.7.-   *Protein Kinases *Arabidopsis Proteins Membrane Proteins. Plant Cell Environ. 2011 Nov;34(11):1944-57.
RNF185 protein, human  EC 6.3.2.19   *Mitochondrial Proteins *Ubiquitin-Protein Ligases Membrane Proteins RING Finger Domains. PLoS One. 2011;6(9):e24367.
LRRC52 protein, mouse  0   *Membrane Proteins. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19419-24
TMEM20 protein, human  0   *Carrier Proteins *Membrane Proteins. oc Natl Acad Sci U S A. 2011 Nov 29;108(48):19234-9
PRRT2 protein, human  0   *Membrane Proteins *Nerve Tissue Proteins Proline. Nat Genet. 2011 Dec;43(12):1252-5
Ima1 protein, S pombe  0   *Membrane Proteins *Nuclear Proteins *Schizosaccharomyces pombe Proteins. Genes Cells. 2011 Oct;16(10):1000-11
erlin-1 protein, mouse  0   *Membrane Proteins. Biochem Biophys Res Commun. 2011 Nov 11;415(1):135-40
erlin-2 protein, mouse  0   *Membrane Proteins. Biochem Biophys Res Commun. 2011 Nov 11;415(1):135-40
Brr6 protein, S pombe  0   *Membrane Proteins *Nuclear Proteins *Schizosaccharomyces pombe Proteins. J Cell Biol. 2011 Oct 31;195(3):467-84
BlaR1 protein, Staphylococcus aureus  EC 3.4.24.-   *Bacterial Proteins *Metalloendopeptidases Membrane Proteins Intracellular Signaling Peptides and Proteins. Antimicrob Agents Chemother. 1993 May;37(5):1144-9.
PspC protein, E coli  0   *Trans-Activators *Escherichia coli Proteins Membrane Proteins. J Mol Biol. 1991 Jul 5;220(1):35-48.
Snorc protein, mouse  0   *Membrane Proteins *Proteoglycans. Osteoarthritis Cartilage. 2011 Aug;19(8):1026-35.
SVIP protein, mouse  0   *Carrier Proteins *Membrane Proteins. PLoS One. 2011;6(8):e24478.
SYNGR4 protein, human  0   *Membrane Proteins.
SYNGR2 protein, human  0   *Membrane Proteins.
SVIP protein, human  0   *Carrier Proteins *Membrane Proteins. J Biol Chem. 2007 Nov 23;282(47):33908-14.
cSN50 peptide  0   *Membrane Proteins *Peptides, Cyclic. J Biol Chem. 2000 Jun 2;275(22):16774-8.
FAM168B protein, human  0   *Membrane Proteins *Nerve Tissue Proteins. J Cell Mol Med. 2011 Aug;15(8):1713-25.
WIPI-2 protein, human  0   *Carrier Proteins *Membrane Proteins. J Cell Mol Med. 2011 Sep;15(9):2007-10.
YIPF4 protein, human  0   *Membrane Proteins. Cell Struct Funct. 2011 Sep 1;36(2):171-85.
Hadp1 protein, zebrafish  0   *Muscle Proteins *Zebrafish Proteins Membrane Proteins. Dis Model Mech. 2011 Sep-Oct;4(5):607-21.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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