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Meprobamate

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Definition: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)     
Pharmacological Action Anti-Anxiety Agents; Anticonvulsants; Hypnotics and Sedatives; Muscle Relaxants, Central
Other names Reid Rowell Brand of Meprobamate; Meprobamate Wyeth Brand; Meprobamate Richard Brand; Meprobamate Reid-Rowell Brand; Meprobamate Kade Brand; Meprobamate Alter Brand; Wyeth Brand of Meprobamate; Wallace Brand 2 of Meprobamate; Wallace Brand 1 of Meprobamate; Visano; Tranmep; Sanofi Synthelabo Brand of Meprobamate; Richard Brand of Meprobamate; Reid-Rowell Brand of Meprobamate; M+¬probamate Richard; Miltown; Meprospan; Kade Brand of Meprobamate; Equanil; DapazDrugs* : MILTOWN; TRANMEP; MEPROBAMATE; AMOSENE; MEPROSPAN; BAMATE; MEPRIAM; EQUANIL; NEURAMATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Stopayne  0   *Acetaminophen *Codeine *Meprobamate Drug Combinations. S Afr Med J 1985;67(9):325
Kominek's mixture  81424-60-4 Benzoic acid, 2-(acetyloxy)-, mixt. with 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine, 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 2-methyl-2-propyl-1,3-propanediyl dicarbamate and N,N,alpha-trimethyl-10H-phenothiazone-10-ethanamine mono  *Aspirin *Chlorpromazine *Meprobamate *Phenobarbital *Promethazine Drug Combinations. Stomalologiia (Mosk) 1981;60(6):24
Tenavoid  0   *Bendroflumethiazide *Meprobamate Drug Combinations. Br J Clin Pract 1981;35(11-12):403
mepronizine  51848-48-7 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)ethanone, mixture with 2-methyl-2-propyl- 1,3-propanediyl dicarbamate  *Acepromazine *Meprobamate Drug Combinations Isomerism. Nouv Presse Med 8(31):2571;1979
Kaologeais  78039-88-0 Karaya gum, mixt. with kaolin, magnesium oxide, magnesium sulfate (1:1), 2-methyl-2-propyl-1,3-propanediyl dicarbamate and pectin  *Kaolin *Karaya Gum *Meprobamate Drug Combinations. Med Chir Dig 8(3):263;1979
dolo visano  76404-04-1 Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, phosphate (1:1) (salt), mixt. with 4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, 2-(diphenylmethoxy)-N,N-dimethylethanamine hydrochloride, 2-methyl-2  *Aspirin *Codeine *Diphenhydramine *Meprobamate *Nicotinic Acids Drug Combinations. Fortschr Med 97(16):791;1979
diphenhydramine, meprobamate, nicotinic acid, pentaerythritol tetranitrate, drug combination  0   *Diphenhydramine *Meprobamate *Nicotinic Acids *Pentaerythritol Tetranitrate Drug Combinations. Fortschr Med 1981;99(41):1714
premenstrone  78393-41-6 Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-(trifluoromethyl)-, (6alpha)-, mixt. with 3,4-dihydro-3-pentyl-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1 dioxide and 2-methyl-2-propyl-1,3-propanediol dicarbamate  *Meprobamate Drug Combinations Hydroflumethiazide/*analogs & derivatives Progesterone/*analogs & derivatives. Z Allgemeinmed 50(7):360;1974
meprocalm  8060-44-4 Meprocalm  *Meprobamate *Reserpine Drug Combinations. Acta Neurol Belg 73(2):88;1973
aspirin, meprobamate drug combination  0   *Aspirin *Meprobamate Drug Combinations.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Hypnotics and Sedatives
Curr Ther Res 16(9):928;1974; Perspect Biol Med 19(4):539;1976EQUAGESIC; MEPRO-ASPIRIN; MEPROBAMATE AND ASPIRIN; Q-GESIC; MICRAININ
folescutol, meprobamate, paraflutizide, rescinnamine drug combination  0   *Benzothiadiazines *Meprobamate *Morpholines Drug Combinations.
meprobamate, oxyphencyclimine drug combination  0   *Meprobamate *Pyrimidines Drug Combinations.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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