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Metallothionein

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Definition: A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains no aromatic amino acids. Metallothionein shows high affinity for bivalent heavy metals.  /biosyn /physiol permitted    Other names Metallothionein IIA; Metallothionein II; Metallothionein I; Metallothionein B; Metallothionein A; Isometallothionein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CUP1-2 protein, S cerevisiae  0   *Metallothionein *Saccharomyces cerevisiae Proteins Copper. Appl Biochem Biotechnol. 2011 Aug;164(8):1278-91
MTL-2 protein, C elegans  0   *Metallothionein *Caenorhabditis elegans Proteins. PLoS One 2010;5(11):e14052
MTL-1 protein, C elegans  0   *Metallothionein *Caenorhabditis elegans Proteins. PLoS One 2010;5(11):e14052
metallothionein-4, human  0   *Metallothionein. Biol Trace Elem Res 2010 oct;137(1):55-62
EmtinB peptide  0   *Peptides Metallothionein. J Neurochem 2008 Jan;104(1):21-37
metallothionein 1E protein, human  0   *Metallothionein. Tumour Biol 2009;30(2):93-9
MT1A protein, human  0   *Metallothionein. Mol Genet Metab 2008 May;94(1):98-104
metallothionein-1, mouse  0   *Metallothionein. FEBS Lett 2007 Oct 16;581(25):5003-8
metallothionein-4, mouse  0   *Metallothionein. Protein J 2005 Aug;24(6):327-36
MT1c protein, Arabidopsis  0   *Metallothionein *Arabidopsis Proteins. Mol Gen Genet 1995 Aug 21;248(3):318-28
MT1b protein, Arabidopsis  0   *Metallothionein *Arabidopsis Proteins. Mol Gen Genet 1995 Aug 21;248(3):318-28
MT1F protein, human  0   *Metallothionein. Yale J Biol Med 2003 Mar 1;76(2):55-62
CUP1-1 protein, S cerevisiae  0   *Metallothionein Copper.
MT1G protein, human  0   *Metallothionein. Oncogene. 2005 Mar 24;24(13):2204-17
MT1A protein, Arabidopsis  0   *Metallothionein *Arabidopsis Proteins.
metallothionein 2 protein, rat  0   *Metallothionein Zinc.
Mt2 protein, mouse  0   *Metallothionein Zinc.
MT2A protein, human  0   *Metallothionein Zinc.
MT2 protein, Crassostrea gigas  0   *Metallothionein. Gene 2001 Jul 25;273(1):123-30
MZm3-4 protein, Zea mays  0   *Metallothionein *Plant Proteins. Gene 2000 Aug 22;254(1-2):199-208
Crd2 protein, Candida albicans  0   *Fungal Proteins *Metallothionein. J Bacteriol 2000 Sep;182(17):4899-905
metallothionein isoform 1  0   *Metallothionein Protein Isoforms. Prostate 2000 May 1;43(2):125-35
tesmin  0   *Metallothionein Biological Markers. Genomics 1999 Apr 1;57(1);130-6
cadmium-metallothionein complex  0   *Metallothionein Cadmium. Toxicol Appl Pharmacol 1998 Nov;153(1):48-58
MT-2 protein, Oryza sativa  0   *Metallothionein *Plant Proteins. Plant Mol Biol 1996 Nov;32(3):525-9
MT1A protein, Gossypium hirsutum  0   *Metallothionein *Plant Proteins. Plant Mol Biol 1996 Jun;31(3):701-5
MT2A protein, Arabidopsis  0   *Metallothionein *Arabidopsis Proteins Zinc. Plant Mol Biol 1996 Mar;30(6):1169-79
metallothionein-streptavidin, recombinant  0   *Bacterial Proteins *Metallothionein Recombinant Fusion Proteins. Bioconj Chem 1995 Jan-Feb;6(1):139-44
METAL1 protein, Coffea arabica  0   *Metallothionein *Plant Proteins. Plant Physiol 1995 Jan;107(1):295-6
CRS5 protein, S cerevisiae  0   *Metallothionein *Saccharomyces cerevisiae Proteins. J Biol Chem 1994 Oct 14;269(41):25295-302
smtA protein, Synechococcus  0   *Bacterial Proteins *Metallothionein. Mol Microbiol 1993 Jan;7(2):177-87
growth inhibitory factor  0   *Nerve Tissue Proteins Alzheimer Disease Metallothionein.
Pharma Action Growth Inhibitors 		EMBO J 1992 Dec;11(13):4843-50
Ec protein, Triticum aestivum  147955-31-5   *Metallothionein *Plant Proteins. Eur J Biochem 1992 Nov 1;209(3):971-6
aurothionein  0   *Metallothionein Gold. Methods Enzymol 1991;205:469-75
IDS-1 protein, Hordeum vulgare  138672-77-2   *Plant Proteins Metallothionein. Plant Mol Biol 1991;17(3):531
platinum-metallothionein complex  0   *Metallothionein *Organoplatinum Compounds. Contrib Nephrol 1990;83:208
metalloselenonein  134646-22-3 Metallothionein (Neurospora crassa copper-binding peptide moiety reduced), 3-(3-selenyl-L-alanine)-5-(3-selenyl-L-alanine)-11-(3-selenyl-L-alanine)-13-(3-selenyl-L-alanine)-17-(3-selenyl-L-alanine)-19-(3-selenyl-L-alanine)-22-(3-selenyl-L-alanine)  *Metallothionein. Proc Natl Acad Sci USA 1991;88(8):3057
technetium Tc 99m metallothionein  0   *Metallothionein *Organotechnetium Compounds. J Nucl Med 1989;30(8):1351
ferrous-metallothionein  0   *Ferrous Compounds *Metallothionein. Eur J Biochem 1988;171(3):711
pseudothioneins  0   *Metallothionein Cadmium. Environ Health Perspect 1986;65:5
lead metallothionein  0   *Metallothionein. Biochem J 1986;233(2):541
cobalt thionein  0   *Metallothionein Cobalt. Biochem Biophys Res Commun 1985;132(1):277
Cd-Zn-metallothionein  0   *Metallothionein. Environ Health Perspect 1984;54:105
metallothionein II hexacosapeptide 36-61  86515-73-3 L-Alanine, L-cysteinyl-L-cysteinyl-L-prolyl-L-valylglycyl-L-cysteinyl-L-alanyl-L-lysyl-L-cysteinyl-L-alanyl-L-glutaminylglycyl-L-cysteinyl-L-isoleucyl-L-cysteinyl-L-lysylglycyl-L-alanyl-L-seryl-L-alpha-aspartyl-L-lysyl-L-cysteinyl-L-seryl-L-cysteinyl-L-c  *Metallothionein *Peptide Fragments. Chem Pharm Bull (Tokyo) 1983;31(6):1885
Hg-Cu-metallothionein  0   *Metallothionein Copper Mercury. Biochem Biophys Res Commun 1983;115(1):167
apothionein  0   *Apoproteins *Metallothionein. Experientia (suppl) 1979;34:241
zinc thionein  0   *Metallothionein Zinc.
Pharma Action Antioxidants ; Radiation-Protective Agents 		Can J Biochem 57(7):1030;1979
copper thionein  0   *Metallothionein. FEBS Letters 44(3):293;1974
cadmium-binding protein  0   *Metallothionein. Arch Biochem Biophys 153(2):755;1972; Chem Biol Interact 25(2-3):127;1979

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