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Metformin

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Definition: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)  a hypoglycemic   
Pharmacological Action Hypoglycemic Agents 		Other names Dimethylguanylguanidine; Glucophage; DimethylbiguanidineDrugs* : GLUCOPHAGE XR; GLUCOPHAGE; FORTAMET; GLUMETZA; RIOMET; METFORMIN HYDROCHLORIDE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
janumet  0   *Metformin *Pyrazines Drug Combinations. Expert Opin Investig Drugs 2008 Oct;17(10):1559-65JANUMET XR; JANUMET
N,N-dimethylbiguanidium  0   Metformin/*analogs & derivatives. Acta Crystallogr C. 2004 Oct;60(Pt 10):o740-43
rosiglitazone-metformin combination  0   *Metformin *Thiazoles Drug Combinations. Med Lett Drugs Ther 2002 Dec 23;44(1146):107-9ROSIGLITAZONE MALEATE; METFORMIN HYDROCHLORIDE; AVANDAMET
metaglip  0   *Glipizide *Metformin Drug Combinations. Med Lett Drugs Ther 2002 Dec 23;44(1146):107-9GLIPIZIDE AND METFORMIN HYDROCHLORIDE; METAGLIP
Glucovance  0   *Glyburide *Metformin. Med Lett Drugs Ther. 2000 Nov 13;42(1092):105-6GLYBURIDE AND METFORMIN HYDROCHLORIDE; GLUCOVANCE
tetrachloro(metformin)platinum(IV)  0   *Organoplatinum Compounds Metformin/*analogs & derivatives. J Inorg Biochem 1997 Oct;68(1):53-9
Glucinan  25672-33-7 Acetic acid, (4-chlorophenoxy)-, compd. with N,N-dimethylimidodicarbonimidic diamide (1:1)  *Glycolates *Metformin Drug Combinations. Journ Annu Diabetol Hotel Dieu :386;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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